Results 141 to 150 of about 3,594,430 (292)
Quality sampling using coiled tubing drilling in deep mineral exploration
, 2012 The sampling time, the costs and its quality are the three factors that determine the best method of drilling in mineral exploration. The two principal methods of reverse circulation (RC) and diamond core drilling are often used in combination by mine ...
Rasouli, Vamegh +2 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
, 2009 The efficient management of the limited energy resources of a wireless visual sensor network is central to its successful operation. Within this context, this paper focuses on the adaptive sampling, forwarding, and routing actions of each node in order ...
Kho, Johnsen +3 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Sub-nyquist sampling techniques [PDF]
, 1990 A number of novel theoretical methods have been developed in an attempt to analyse data produced by sampling a signal at below the Nyquist rate and the limitations of the approaches have been investigated.
Bagshaw, Paul Christopher
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Adaptive Gibbs samplers and related MCMC methods [PDF]
, 2011 We consider various versions of adaptive Gibbs and Metropolis- within-Gibbs samplers, which update their selection probabilities (and perhaps also their proposal distributions) on the y during a run, by learning as they go in an attempt to optimise ...
Rosenthal, Jeffrey S. (Jeffrey Seth) +2 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Adaptive sampling and sensing approach with mobile sensor networks
, 2015 This paper presents an adaptive sampling and sensing method for mobile sensor networks to reduce the number of measurements and the sampling cost based on compressive sensing.
Zhu YL(朱云龙) +2 more
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