Results 61 to 70 of about 260,991 (264)
A new adaptive response surface method for reliability analysis [PDF]
Response surface method is a convenient tool to assess reliability for a wide range of structural mechanical problems. More specifically, adaptive schemes which consist in iteratively refine the experimental design close to the limit state have received ...
Salaün, Michel +2 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Biosensing techniques are progressing rapidly, promising the emergence of sophisticated virtual reality (VR) headsets with versatile biosensing enabling an objective, yet unobtrusive way to monitor the user’s physiology.
K. Pettersson +3 more
doaj +1 more source
Adaptive sampling and reconnaissance surveys for geostatistical mapping of the soil
The effort required to survey a soil variable depends upon the acceptable uncertainty of estimates and the variogram of the variable. The variogram is unknown prior to sampling, so it must be inferred from a reconnaissance survey before an efficient ...
Lark, R. M., Marchant, B. P.
core +1 more source
A high throughput adaptive DFE for HIPERLAN [PDF]
This paper describes two methods for increasing the throughput of an adaptive decision feedback equaliser (DFE) using the LMS training algorithm. In the first method, a signed power-of-two number representation is used for the equaliser input data. Using
Nix, AR, Perry, R, Bull, DR
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fourier Analysis of Stochastic Sampling Strategies for Assessing Bias and Variance in Integration [PDF]
Each pixel in a photorealistic, computer generated picture is calculated by approximately integrating all the light arriving at the pixel, from the virtual scene. A common strategy to calculate these high-dimensional integrals is to average the estimates
Kautz, Jan, Subr, Katric
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

