Results 221 to 230 of about 4,471,539 (245)

Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials

Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, 2021
The thermogenic mechanisms supporting endothermy are still not fully understood in all major mammalian subgroups. In placental mammals, brown adipose tissue currently represents the most accepted source of adaptive non-shivering thermogenesis.
Michael Gaudry, Elias Theodor Polymeropoulos, Martin Jastroch   +2 more
exaly   +3 more sources

Activation of Toll-like Receptor 4 (TLR4) Attenuates Adaptive Thermogenesis via Endoplasmic Reticulum Stress [PDF]

Journal of Biological Chemistry, 2015
Background: Human obesity is associated with defective brown adipose tissue (BAT) activation. Results: Toll-like receptor 4(TLR4) activation by high fat diet or lipopolysaccharide impairs adaptive thermogenesis.
Soonkyu Chung, Anjeza Pashaj, Inhae Kang   +2 more
exaly   +1 more source

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Adaptive thermogenesis in hummingbirds

Journal of Experimental Biology, 2002
SUMMARY The occurrence of non-shivering thermogenesis in birds has long been a controversial issue. Although birds are endothermic vertebrates, sharing with mammals (placental mammals and marsupials) a common ancestor, they do not possess brown adipose tissue or a similar type of tissue, unlike their mammalian counterparts.
José Eduardo P W, Bicudo, Antonio C, Bianco, Cláudia R, Vianna   +2 more
openaire   +2 more sources

Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice [PDF]

Cell Metabolism, 2020
Robert Jansen, Cohen D E, Hayley T Nicholls   +2 more
exaly   +2 more sources

Clinical significance of adaptive thermogenesis

International Journal of Obesity, 2007
The epidemic of obesity is developing faster than the scientific understanding of an efficient way to overcome it, as reflected by the low success rate of short- and long-term weight loss interventions. From a clinical standpoint, this suggests that the body tends to defend a set point of possible genetic origin in the context of a weight-reducing ...
Major, G.C., Doucet, E., Trayhurn, P., Astrup, Arne, Tremblay, A.   +4 more
openaire   +3 more sources

Regulation of Thermogenic Adipocyte Differentiation and Adaptive Thermogenesis Through Histone Acetylation [PDF]

Frontiers in Endocrinology, 2020
Chungang Liu, Reinhard Brunmeir, Belinda X Ong   +2 more
exaly   +2 more sources

Adaptive thermogenesis with weight loss in humans

Obesity, 2013
AbstractAdaptive thermogenesis (AT) with weight loss refers to underfeeding‐associated fall in resting and non‐resting energy expenditure (REE, non‐REE); this is independent of body weight and body composition. In humans, the existence of AT was inconsistently shown and its clinical significance has been questioned.Objectives:Discrepant findings are ...
M J, Müller, A, Bosy-Westphal
openaire   +2 more sources

The sarcoplasmic reticulum and SERCA: a nexus for muscular adaptive thermogenesis

Applied Physiology, Nutrition, and Metabolism, 2020
We are currently facing an “obesity epidemic” worldwide. Promoting inefficient metabolism in muscle represents a potential treatment for obesity and its complications. Sarco(endo)plasmic reticulum (SR) Ca2+-ATPase (SERCA) pumps in muscle are responsible for maintaining low cytosolic Ca2+ concentration through the ATP-dependent pumping of Ca2+ from the
Gamu, Daniel, Juracic, Emma Sara, Hall, Karlee Jenna, Tupling, A. Russell   +3 more
openaire   +2 more sources

Glycogen synthesis is required for adaptive thermogenesis in beige adipose tissue and affects diet-induced obesity.

American Journal of Physiology. Endocrinology and Metabolism
Glycogen is a form of energy storage for glucose in different tissues such as liver and skeletal muscle. It remains incompletely understood how glycogen impacts on adipose tissue functionality.
Shixuan Zhuo, Meijuan Bai, Zi-Nan Wang, Lingling Chen, Zixuan Li, Jin-Zhu Chen, Xiaoyi Ye, Cheng Guo, Yan Chen   +8 more
semanticscholar   +1 more source

Fattening the role of Ca2+ cycling in adaptive thermogenesis

Nature Medicine, 2017
A new study shows that deleting uncoupling protein 1 activates Ca2+ cycling thermogenesis within beige fat, protecting mice against cold-induced hypothermia and dysglycemia following diet-induced obesity.
Daniel Gamu, A Russell Tupling
openaire   +2 more sources