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In-depth analysis of the RNA editing landscape in intracranial aneurysms and its potential role in alternative splicing. [PDF]
Wang Y +5 more
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The Role of Chemical Modifications in the Genome of Negative-Sense RNA Viruses on the Innate Immune Response. [PDF]
Ceballos MA, Acevedo ML.
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Distinguishing self from non-self RNA by editing-specific inosine patterns
Varada R +20 more
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RNA Editing by Mammalian ADARs
2011The main type of RNA editing in mammals is the conversion of adenosine to inosine which is translated as if it were guanosine. The enzymes that catalyze this reaction are ADARs (adenosine deaminases that act on RNA), of which there are four in mammals, two of which are catalytically inactive. ADARs edit transcripts that encode proteins expressed mainly
Marion, Hogg +3 more
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ADAR Proteins: Structure and Catalytic Mechanism
2011Since the discovery of the adenosine deaminase (ADA) acting on RNA (ADAR) family of proteins in 1988 (Bass and Weintraub, Cell 55:1089-1098, 1988) (Wagner et al. Proc Natl Acad Sci U S A 86:2647-2651, 1989), we have learned much about their structure and catalytic mechanism.
Rena A, Goodman +2 more
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