Results 201 to 210 of about 42,601 (251)

RNA Editing-MediatedCorrection of TP53 Nonsense Mutationsvia Lipid Nanoparticle-Delivered Circular ADAR-Recruiting RNAs

open access: green
Jinjin Wang (394128)   +8 more
openalex   +1 more source

Distinguishing self from non-self RNA by editing-specific inosine patterns

open access: yes
Varada R   +20 more
europepmc   +1 more source
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RNA Editing by Mammalian ADARs

2011
The main type of RNA editing in mammals is the conversion of adenosine to inosine which is translated as if it were guanosine. The enzymes that catalyze this reaction are ADARs (adenosine deaminases that act on RNA), of which there are four in mammals, two of which are catalytically inactive. ADARs edit transcripts that encode proteins expressed mainly
Marion, Hogg   +3 more
openaire   +2 more sources

ADAR Proteins: Structure and Catalytic Mechanism

2011
Since the discovery of the adenosine deaminase (ADA) acting on RNA (ADAR) family of proteins in 1988 (Bass and Weintraub, Cell 55:1089-1098, 1988) (Wagner et al. Proc Natl Acad Sci U S A 86:2647-2651, 1989), we have learned much about their structure and catalytic mechanism.
Rena A, Goodman   +2 more
openaire   +2 more sources

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