Results 171 to 180 of about 345,011 (278)

Pharmacokinetic and Pharmacodynamic Modeling of Antibody-Drug Conjugates. [PDF]

Cancers (Basel)
Glassman PM.
europepmc   +1 more source

Optimizing Body Size‐Based Dosing Approaches for Antibody–Drug Conjugates

Clinical Pharmacology &Therapeutics, EarlyView.
Optimized dosing precision of antibody–drug conjugates (ADCs) remains challenging due to narrow therapeutic indices, efficacious doses near the maximum tolerated dose, and substantial interindividual variability in exposure. Body size‐based dosing can reduce exposure variability when the allometric scaling exponent for clearance α = 1 but may over‐ or ...
Andrew B. SyBing, Diane D. Wang
wiley   +1 more source

Integrating In Vitro Analytics for Improved Antibody-Drug Conjugate Candidate Selection. [PDF]

Cancers (Basel)
Del Solar V, Saleh A, Di Tacchio A, Becciolini LS, Kang GD, Jackowska B, Hu Y, Gong C, Zhang A, Hostetler L, Lee M, Khan AH, Mitra A, Ahmed M, Tickle D, Vijayakrishnan B.   +15 more
europepmc   +1 more source

Synergistic Enhancement of Modified‐PVDF Humidity Sensitivity via Chemical Adsorption‐Ionic Conductivity and its Application in Intelligent Powered Air‐Purifying Respirator

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The study developed a PVDF/SiO2 humidity sensor with superhydrophobic properties and integrated the humidity sensor into the intelligent powered air‐purifying respirator (IPAPR) for breath monitoring. Coupled with the Gated Recurrent Unit (GRU) machine learning prediction algorithm, it enables feedforward control of the fan to achieve respiratory ...
Xinjian He, Hongwei Liu, Xianjie Xu, Xinkai Qi, Danhong Gao, Hanling Deng, Dusong Hou, Qianyao Lu, Lei Zhu, Sheng Huang   +9 more
wiley   +1 more source

Multiparametric Breast MRI for the Differentiation of Atypical Ductal Hyperplasia and Ductal Carcinoma In Situ in Postmenopausal Women. [PDF]

Cureus
Mihajlovic MN, Raspopovic LJ, Dimitrijevic D, Krusac IB, Djajic A, Nadrljanski MM.   +5 more
europepmc   +1 more source

Real‐Time Phosphate Monitoring via Plant‐Derived Graphene Ink FET Sensors Integrated with Deep Learning

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Accurate, real‐time nutrient monitoring is challenging in precision agriculture due to cost and technical limitations. Aligned with circular green economics, a deep learning‐integrated remote‐gate field‐effect transistor sensor with plant‐derived graphene electrodes offers a sustainable solution.
Rapti Ghosh, Fengxue Zhang, Hyun‐June Jang, Janan Hui, Kayla Vittore, Haoyang You, Rozyyev Vepa, Wen Zhuang, Xingkang Huang, Haihui Pu, Jeffrey W. Elam, Stuart J. Rowan, DoKyoung Lee, Elizabeth A. Ainsworth, Mark C. Hersam, Yuxin Chen, Junhong Chen   +16 more
wiley   +1 more source

Superionic Conduction Through Lattice Engineering of Fluorites Stabilizing Periodic Oxygen Vacancy Network

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Lattice‐engineered fluorite oxide with periodic oxygen vacancy network achieves superionic conduction, Ce4+–Al3+ fluorite cation ordering enables dielectric‐enhanced superionic conduction, surpassing the limitations of conventional doped electrolytes and high fuel cell performance at low temperature through a flattened energy landscape.
Shahzad Rasool, Muhammad Faisal Anwar, Sarfraz, Nabeela Akbar, Wei Zhou, Shuo Wan, Rizwan Raza, Muhammad Afzal, Li Sun, Chenjie Lou, Mingxue Tang, Aristides D. Zdetsis, Hind Himayyid Aljaddani, Mohamed Elfleet, Peter D. Lund, Muhammad Imran Asghar, Yifu Jing, Qi Fan, Bin Zhu   +18 more
wiley   +1 more source

Engineered Metal–Organic Frameworks‐Based Materials for Environmental Detection

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Engineered metal–organic frameworks (MOFs) regulated by various material modification strategies are discussed for environmental contaminant detection under different sensing mechanisms, providing future improvements of MOFs in environmental detection. Sensitive and selective detection of contaminants is crucial for environmental protection.
Pan Gao, Song Wang, Yuechao Yao, Yibo Dou   +3 more
wiley   +1 more source

Amide proton transfer-weighted imaging in predicting aggressiveness of hepatocellular carcinoma: comparison with diffusion-weighted imaging. [PDF]

Quant Imaging Med Surg
Huang J, Shen D, Sun J, Shi J, Dou W, Prince M, Ye J, Luo X.   +7 more
europepmc   +1 more source

Digital Rights Activism in Multilevel Governance

European Policy Analysis, EarlyView.
ABSTRACT Multilevel governance (MLG) without a clear hierarchical structure can create power imbalances among various actors, particularly in settings with overlapping jurisdictions and policy areas. This dynamic is especially pronounced in Internet governance, which faces a complex interplay of domestic laws, state interdependence, and heightened ...
Alison Harcourt
wiley   +1 more source