Results 201 to 210 of about 345,011 (278)

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

Establishment of Machine Learning Models for Estimating the Collagen Content of Uterine Leiomyomas and Prediction of the Effect of Gonadotropin-Releasing Hormone Analog. [PDF]

Reprod Med Biol
Tamehisa T, Sato S, Tamura I, Tanabe M, Ito K, Sugino N.   +5 more
europepmc   +1 more source

Virtual Magnetic Resonance Elastography Using a Deep Generative Model for Liver Fibrosis Staging

iRADIOLOGY, EarlyView.
The proposed Registration‐based Generative Adversarial Network‐Convolutional Block Attention Module (RegGAN‐CBAM) model efficiently and reliably generates virtual MR elastography using diffusion weighted imaging. Strong correlation between virtual and native MR elastography for liver stiffness and viscosity are observed.
Longyu Sun, Yikun Wang, Yan Li, Xumei Hu, Wenyue Mao, Mengting Sun, Zian Wang, Fuhua Yan, Ruokun Li, Chengyan Wang   +9 more
wiley   +1 more source

A 5000 Fps, 4 Megapixel, Radiation-Tolerant, Wafer-Scale CMOS Image Sensor for the Direct Detection of Electrons and Photons. [PDF]

Sensors (Basel)
Scott A, Bauzà C, Bofill-Petit A, Font A, Gargallo M, Gifreu R, Latif K, Mollà Garcia A, Sannino M, Turchetta R.   +9 more
europepmc   +1 more source

Optimizing Detection Schemes for Broadband Pump‐Probe Microscopy

Microscopy Research and Technique, EarlyView.
Small spot sizes and broadband spectral coverage create unusual noise challenges for broadband pump‐probe microscopy. Analysis of probe and detector noise characteristics can provide strategies for mitigating these challenges. ABSTRACT Although similar to more commonly implemented single wavelength approaches, broadband pump‐probe or transient ...
Kendall Benton, Emma Orcutt, Skyler Hollinbeck, Erik M. Grumstrup   +3 more
wiley   +1 more source

Non-Invasive, High-Resolution (¹H₂O) Metabolic Activity Diffusion Imaging [MADI] of Rat Glioma. [PDF]

NMR Biomed
Schlegel JW, Holland SM, Kelly FD, Baker EM, Stoller J, Packwood W, Li X, Barajas RF, Springer CS, Pike MM.   +9 more
europepmc   +1 more source

Tele‐hospitalist services to support the opening of a new rural hospital

Journal of Hospital Medicine, EarlyView.
Abstract As rural hospitals experiencing low patient volume and workforce shortages continue to close nationally, we present an innovative telemedicine care delivery model utilized to support the opening of a new 25‐bed rural hospital in South Carolina in 2023.
Yotam Papo, Jillian Harvey, Dunc Williams Jr., Kit N. Simpson, Jay Hinesley, Allen Abernethy, Dee W. Ford, Marc Heincelman   +7 more
wiley   +1 more source

Recent advances in bispecific antibody-drug conjugates for breast cancer therapy. [PDF]

Cancer Chemother Pharmacol
Ji X, Yang Y, Ma C, Huang W, Guo S, Wang L, Zheng H, Wu X.   +7 more
europepmc   +1 more source

Contrast‐Enhanced MR Fingerprinting With Delta‐Relaxometry: Investigating a New Avenue for Tumor Characterization

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI contrast agents enhance lesion characterization by altering tissue relaxation properties. However, quantitative assessment of contrast enhancement is limited by variability in contrast administration parameters, and lack of efficient and precise contrast concentration independent relaxivity (r1, r2) measurement techniques.
Shengwen Deng, Walter Zhao, Sree Gongala, Jessie E. P. Sun, David W. Jordan, Chris A. Flask, Mark A. Griswold, Dan Ma, Chaitra Badve   +8 more
wiley   +1 more source

Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates. [PDF]

Nat Commun
Ochtrop P, Jagtap AP, Felber JG, Vogt S, Herterich S, Mai I, Cyprys P, Schmitt S, Payer S, Kitowski A, Wunder S, Machui P, Brandmeier J, Leonardi N, Poliak E, Hackenberger CPR, Marcq O, Schumacher D, Helma J, Vogl AM, Kasper MA.   +20 more
europepmc   +1 more source