Results 211 to 220 of about 176,033 (310)

Impact of ADC Value on Conversion Surgery for Unresectable Colorectal Liver Metastasis. [PDF]

In Vivo
Yamada S, Ikemoto T, Saito YU, Teraoku H, Soyama A.   +4 more
europepmc   +1 more source

Synthesis of a Stable Hydrophilic trans‐Cyclooctene Amino Acid Unlocks Fast Bioorthogonal Click Chemistry for the Generation of Antibody‐Drug Conjugates by Genetic Code Expansion

Angewandte Chemie International Edition, EarlyView.
A novel trans‐cyclooctene (TCO) based noncanonical amino acid (ncAA) is reported, characterized by high hydrophilicity and remarkable stability to trans‐cis isomerization. Its incorporation via genetic code expansion into an antibody and subsequent conjugation resulted in a highly efficacious antibody‐drug conjugate (ADC).
Georgi R. Genov, Dina Osmanović, Ines Bašić, Christine Koehler, Paul F. Sauter   +4 more
wiley   +1 more source

The "ADC-after-ADC" paradigm: navigating cross-resistance and sequencing in breast cancer therapy. [PDF]

Front Oncol
Asare M, Okobi TO, Karass S, Okobi JT, Taiwo E.   +4 more
europepmc   +1 more source

Leveraging Metamaterial‐Inspired Wireless Resonator for Reliable Quantitative MRI at 1.5T: Linearity, Bias, and Repeatability Assessment

Advanced Physics Research, EarlyView.
This study designed a nonlinear‐response metamaterial‐inspired wireless resonator (MWR) and systematically evaluated the feasibility of using MWR for quantitative magnetic resonance imaging (qMRI), including T1/T2 mapping, apparent diffusion coefficient, and proton density fat fraction.
Yakui Wang, Yingyi Qi, Bing Liu, Zhonghai Chi, Yi Yi, Xinxin Li, Yibei Yu, Qian Zhao, Zhuozhao Zheng   +8 more
wiley   +1 more source

Organic Cosolvent-Free Antibody-Drug Conjugation Enabled by Hydrophilic Linker-Payloads. [PDF]

ACS Omega
Matsuda Y, Cheng H, Hartung J, Schwartz I, Li H, Chang JR, Watson SS, Mahajan R, Mendelsohn BA, Martinelli MJ.   +9 more
europepmc   +1 more source

Physical Reservoir Computing Using Microelectromechanical Systems

Advanced Physics Research, EarlyView.
Physical reservoir computing (PRC) transforms micro‐electro‐mechanical (MEMS) sensors into intelligent computing nodes by utilizing their intrinsic nonlinear dynamics and short‐term memory effects. This review surveys recent progress in MEMS‐based reservoir computing, covering its theoretical foundations, device architectures, and applications in ...
Mariam Gada, Nizar Jaber, Nazek El‐Atab   +2 more
wiley   +1 more source

Ultrafast RF Spectrum Analyzer Assisted by Optical Short‐Time Fourier Transform

Advanced Physics Research, EarlyView.
We present Recent efforts in an ultrafast RF spectrum analyzer based on the short‐time Fourier transform (STFT) at over 10 MHz frame rate and over 40GHz bandwidth to improve performance and support applications. All these efforts could inspire more innovative applications of temporal imaging modalities in the future.
Liao Chen, Yufan Du, Rongwu Liu, Chi Zhang, Xinliang Zhang   +4 more
wiley   +1 more source

The next click in antibody drug conjugate development. [PDF]

Cell Rep Med
Gupta A, Chandarlapaty S.
europepmc   +1 more source

A Proxy ADC Framework for Side-Channel Secure ADC Analysis

IEEE Open Journal of Circuits and Systems
Andrew Ash, John Hu
openaire   +2 more sources

Postcranial anatomy and osteohistology of an early prozostrodont cynodont from the Upper Triassic of Brazil

The Anatomical Record, EarlyView.
Abstract Prozostrodon brasiliensis, a probainognathian cynodont of the clade Prozostrodontia, is recognized as a key taxon for understanding the origin of Mammaliaformes and mammals. Despite detailed investigations of its cranial anatomy, the postcranial skeleton has received comparatively less attention.
Iasmim M. Michelotti, Lívia Roese‐Miron, Brodsky Dantas Macedo Farias, Marina Bento Soares, Leonardo Kerber   +4 more
wiley   +1 more source