Results 31 to 40 of about 176,033 (310)

Een inventariserend veldonderzoek in de vorm van een karterend booronderzoek

, 2021
ADC ArcheoProjecten heeft in april 2021 een inventariserend veldonderzoek, karterende fase, uitgevoerd op de locatie Driehoeksperceel project N2000 Willinks Weust, gemeente Wintereswijk.
Jansen, B. (ADC ArcheoProjecten), B. Jansen   +1 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

ADC rapport 4783

, 2020
ADC ArcheoProjecten heeft in november 2018 een bureauonderzoek en Inventariserend veldonderzoek uitgevoerd voor de locatie Lekdijk 384 te Nieuw-Lekkerland, gemeente Molenwaard.
Bouter, H.E. (ADC ArcheoProjecten), H.E. Bouter   +1 more
core   +1 more source

Dental management of Fanconi anemia: a rare congenital disorder

Journal of Rare Diseases
Purpose Fanconi anemia is a rare inherited genetic disorder that is characterized by all three defective blood cell lines such as reduced red blood cells, platelets, and white blood cells.
Jacqueline Jacinta Dias, Ankit Gupta, A. K. Shreehari   +2 more
doaj   +1 more source

Analysis of programs for calculation of the system characteristics of ultra-wide range receiving paths

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2021
When designing radio engineering products, at the early stages,one of the most important tasks to be solved is to determine the effective version of the system/device by analyzing all possible available versions.
D. V. Arkhipenkov
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Maytansine-bearing antibody-drug conjugates induce in vitro hallmarks of immunogenic cell death selectively in antigen-positive target cells

OncoImmunology, 2019
Oncology treatment has been revolutionized by the introduction of immune checkpoint inhibitor drugs, which enable 20–40% of patients to generate anti-tumor immune responses.
Maxine Bauzon, Penelope M. Drake, Robyn M. Barfield, Brandon M. Cornali, Igor Rupniewski, David Rabuka   +5 more
doaj   +1 more source

Policy Considerations on the Interplay Between State Aid Control and Competition Law

Market and Competition Law Review, 2017
Under the broad topic of the interplay between state aid and competition law, this article addresses the following related lines of discussion: (i) the goals and some of the political rationales of state aid control; (ii) a brief illustration of some of
Maria João Melícias
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

ADC rapport 5035

, 2019
ADC ArcheoProjecten heeft een Inventariserend Veldonderzoek (IVO) in de vorm van proefsleuven, variant archeologische begeleiding (KNA 4.1 protocol 4003), uitgevoerd voor het plangebied Bovenkerkseweg 33b te Giessenburg, in het kader van de geplande ...
Semeijn, R. (ADC Archeoprojecten), Benthem, A. van (ADC Archeoprojecten), Jansen, B. (ADC Archeoprojecten), Bot, M.C.J. (ADC Archeoprojecten), Dijkstra, J. (ADC Archeoprojecten), Beckers, I.S.J. (ADC Archeoprojecten), Jezeer, W. (ADC ArcheoProjecten), Loopik, J. (ADC Archeoprojecten), Muller, A. (ADC Archeoprojecten), Bouter, H.E. (ADC Archeoprojecten), Nieuwlaat, G. (ADC Archeoprojecten), Boer, G.H. de (ADC ArcheoProjecten), Geerts, R.C.A. (ADC Archeoprojecten), Hanemaaijer, M. (ADC Archeoprojecten), Verduin, J.T. (ADC ArcheoProjecten), Zee, R.M. van der (ADC ArcheoProjecten), Waldus, W.B. (ADC Archeoprojecten), Stevens, F. (ADC ArcheoProjecten), Jacobs, E. (ADC ArcheoProjecten), A. van Benthem, R.C.A. Geerts, F. Stevens, G. Nieuwlaat, M.C.J. Bot, R. Semeijn, M. Hanemaaijer, G.H. de Boer, B. Jansen, A. Muller, W.B. Waldus, J. Loopik, J. Dijkstra, H.E. Bouter, R.M. van der Zee, E. Jacobs, W. Jezeer, J.T. Verduin, I.S.J. Beckers   +37 more
core   +1 more source