Results 31 to 40 of about 101,310 (266)

A Prospective Study on the Role of Diffusion Weighted MR Imaging in Charcterisation of Breast Masses [PDF]

International Journal of Anatomy Radiology and Surgery, 2016
Introduction: Breast MRI has been widely used for the detection, diagnosis and staging of breast cancer. Even though lower ADC, which is the objective measure of the diffusivity has been proved too strongly associated with malignant tumours, the ...
Rajalakshmi Preethi G, Mariappan Murugan, Mahesh K Mitttal, Brij Bhushan Thukra   +3 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Development and implementation of a gyrolab-based generic anti-drug antibody assay for antibody-drug conjugates in cynomolgus monkey studies

Frontiers in Immunology
IntroductionNon-clinical immunogenicity yields valuable insights into pharmacokinetics, efficacy, and safety. Given the complex nature of ADC therapeutics, early detection of anti-drug antibodies (ADAs) is critical for elucidating exposure and toxicity ...
Runzhong Fu, Runzhong Fu, Christine O’Day, Razieh Esmaeili, Stavros Zinonos, Arlan Martin, Lisa McCulloch, Charles Y. Tan   +7 more
doaj   +1 more source

Antibody Conjugates-Recent Advances and Future Innovations

Antibodies, 2020
Monoclonal antibodies have evolved from research tools to powerful therapeutics in the past 30 years. Clinical success rates of antibodies have exceeded expectations, resulting in heavy investment in biologics discovery and development in addition to ...
Donmienne Leung, Jacqueline M. Wurst, Tao Liu, Ruben M. Martinez, Amita Datta-Mannan, Yiqing Feng   +5 more
doaj   +1 more source

A 12 bit 76MS/s SAR ADC with a Capacitor Merged Technique in 0.18µm CMOS Technology [PDF]

Journal of Electrical and Computer Engineering Innovations, 2017
A new high-resolution and high-speed fully differential Successive Approximation Register (SAR) Analog to Digital Converter (ADC) based on Capacitor Merged Technique is presented in this paper.
S. Mahdavi
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

La libertad de expresión en Argentina y su comparación con la jurisprudencia de la Corte Interamericana: parecidos y diferencias entre los casos “Patitó” y “Kimel”

Anuario de Derechos Humanos, 2009
El presente comentario analiza, por una parte, los aspectos más relevantes de la sentencia de la Corte Suprema argentina en el caso Patitó, José Angel y otro c. Diario La Nación, del 24 junio de 2008.
Hernán Gullco
doaj   +1 more source

Advances in Combined Immunotherapy for Triple Negative Breast Cancer

Zhongliu Fangzhi Yanjiu, 2022
The triple-negative breast cancer has a relatively poor prognosis with limited therapeutic options. This subtype is highly immunogenetic and exhibits rich tumor infiltrated lymphocytes in the tumor microenvironment.
WANG Hua, HU Xiaolei, LI Xingyu, DAI Ying   +3 more
doaj   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Correlation Between Apparent Diffusion Coefficient and IDH-1/1p19q Genotype of Glioma

Zhongliu Fangzhi Yanjiu, 2023
Objective To investigate the correlation between ADC value and glioma IDH-1/1p19q genotype. Methods The MRI features and molecular pathological results of 69 patients with pathologically confirmed diagnosis of WHO grade Ⅱ/Ⅲ glioma between March 2013 and ...
SUN Pengfei, MOU Fuling, MA Li, FU Zhengfeng   +3 more
doaj   +1 more source