Results 31 to 40 of about 347,135 (294)

IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways. [PDF]

, 2018
Lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC) are two distinct and predominant types of human lung cancer. IκB kinase α (IKKα) has been shown to suppress lung SCC development, but its role in ADC is unknown.
Hu, Yinling, Johnson, Peter F, Karin, Michael, Ma, Buyong, Nussinov, Ruth, Schrump, David S, Song, Na-Young, Su, Ling, Sun, Zhonghe, Wang, Zining, Willette-Brown, Jami, Wu, Xiaolin, Xi, Sichuan, Xia, Xiaojun, Zhu, Feng   +14 more
core   +1 more source

The Structure Of The Accretion Disk In The ADC Source 4U 1822-371 [PDF]

, 2010
The low-mass X-ray binary (LMXB) 4U 1822-371 has an accretion disk corona (ADC) that scatters X-ray photons from the inner disk and neutron star out of the line of sight. It has a high orbital inclination and the secondary star eclipses the disk and ADC.
Ashcraft, T. A., Bayless, A. J., Cornell, M. E., Hynes, R. I., Robinson, E. L.   +4 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Research of data acquisition instrument based on domestic key chip

Dianzi Jishu Yingyong, 2022
The high performance data acquisition system is widely used in scientific research such as high energy physics, particle physics experiment and radiation detection, which is the key equipment of many large scientific experiment.
Zhao Qian, Luo Tongding, Chen Yanli, Wang Jing, Lv Zongjing, Li Haitao, Zhang Yanxia, Ruan Linbo   +7 more
doaj   +1 more source

Equalization-Based Digital Background Calibration Technique for Pipelined ADCs [PDF]

, 2014
In this paper, we present a digital background calibration technique for pipelined analog-to-digital converters (ADCs). In this scheme, the capacitor mismatch, residue gain error, and amplifier nonlinearity are measured and then corrected in digital ...
Moosazadeh, Tohid, Rodríguez Vázquez, Ángel Benito, Yavari, Mohammad, Zeinali, Behzad   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Dental management of Fanconi anemia: a rare congenital disorder

Journal of Rare Diseases
Purpose Fanconi anemia is a rare inherited genetic disorder that is characterized by all three defective blood cell lines such as reduced red blood cells, platelets, and white blood cells.
Jacqueline Jacinta Dias, Ankit Gupta, A. K. Shreehari   +2 more
doaj   +1 more source

Maytansine-bearing antibody-drug conjugates induce in vitro hallmarks of immunogenic cell death selectively in antigen-positive target cells

OncoImmunology, 2019
Oncology treatment has been revolutionized by the introduction of immune checkpoint inhibitor drugs, which enable 20–40% of patients to generate anti-tumor immune responses.
Maxine Bauzon, Penelope M. Drake, Robyn M. Barfield, Brandon M. Cornali, Igor Rupniewski, David Rabuka   +5 more
doaj   +1 more source

La libertad de expresión en Argentina y su comparación con la jurisprudencia de la Corte Interamericana: parecidos y diferencias entre los casos “Patitó” y “Kimel”

Anuario de Derechos Humanos, 2009
El presente comentario analiza, por una parte, los aspectos más relevantes de la sentencia de la Corte Suprema argentina en el caso Patitó, José Angel y otro c. Diario La Nación, del 24 junio de 2008.
Hernán Gullco
doaj   +1 more source

Longitudinal monitoring of Apparent Diffusion Coefficient (ADC) in patients with prostate cancer undergoing MR-guided radiotherapy on an MR-Linac at 1.5 T: a prospective feasibility study

Radiology and Oncology, 2023
Hybrid MRI linear accelerators (MR-Linac) might enable individualized online adaptation of radiotherapy using quantitative MRI sequences as diffusion-weighted imaging (DWI).
Almansour Haidara, Schick Fritz, Nachbar Marcel, Afat Saif, Fritz Victor, Thorwarth Daniela, Zips Daniel, Bertram Felix, Müller Arndt-Christian, Nikolaou Konstantin, Othman Ahmed E, Wegener Daniel   +11 more
doaj   +1 more source