Results 41 to 50 of about 347,135 (294)

Diffusion MR Characteristics Following Concurrent Radiochemotherapy Predicts Progression-Free and Overall Survival in Newly Diagnosed Glioblastoma. [PDF]

, 2015
The standard of care for newly diagnosed glioblastoma (GBM) is surgery, then radiotherapy (RT) with concurrent temozolomide (TMZ), followed by adjuvant TMZ. We hypothesized patients with low diffusivity measured using apparent diffusion coefficient (ADC)
Chang, Warren, Cloughesy, Timothy F, Ellingson, Benjamin M, Hardy, Anthony J, Harris, Robert J, Lai, Albert, Leu, Kevin, Mody, Reema R, Nghiemphu, Phioanh L, Pope, Whitney B   +9 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Enhanced projectile path estimation using multi-vehicle FMCW radar sensors

Scientific Reports
This paper presents an enhanced approach to projectile path estimation using Frequency-Modulated Continuous Wave (FMCW) radar sensors distributed across multiple vehicles in a tactical formation.
Amgad A. Salama, Mahmoud A. Hussein
doaj   +1 more source

Effect of Renal Vein Variations on Apparent Diffusion Coefficient in Asymptomatic Patients

Haseki Tıp Bülteni, 2020
Aim:The aim of this study was to investigate whether renal vein variations had an effect on apparent diffusion coefficient (ADC) values in diffusion magnetic resonance imaging (MRI).Methods:Images of 958 patients who underwent MRI between January 2017 ...
Elif Gündoğdu, Emre Emekli, Mehmet Oğuzman, Mahmut Kebapçı   +3 more
doaj   +1 more source

More than Toxins—Current Prospects in Designing the Next Generation of Antibody Drug Conjugates

Frontiers in Bioscience-Landmark, 2022
Antibody drug conjugates (ADCs) are rapidly becoming a cornerstone in targeted therapies, especially for the treatment of cancer. Currently, there are 12 FDA-approved ADCs, eight of which have been approved within the last five years, with numerous ...
Jonathan Schwach, Mustafa Abdellatif, Andreas Stengl   +2 more
doaj   +1 more source

The Infrared Imaging Spectrograph (IRIS) for TMT: the atmospheric dispersion corrector [PDF]

, 2010
We present a conceptual design for the atmospheric dispersion corrector (ADC) for TMT's Infrared Imaging Spectrograph (IRIS). The severe requirements of this ADC are reviewed, as are limitations to observing caused by uncorrectable atmospheric effects ...
Bauman, Brian J., Cramptone, David, Larkin, James E., Moore, Anna M., Niehaus, Cynthia N., Phillips, Andrew C., Simard, Luc   +6 more
core   +2 more sources

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Development and implementation of a gyrolab-based generic anti-drug antibody assay for antibody-drug conjugates in cynomolgus monkey studies

Frontiers in Immunology
IntroductionNon-clinical immunogenicity yields valuable insights into pharmacokinetics, efficacy, and safety. Given the complex nature of ADC therapeutics, early detection of anti-drug antibodies (ADAs) is critical for elucidating exposure and toxicity ...
Runzhong Fu, Runzhong Fu, Christine O’Day, Razieh Esmaeili, Stavros Zinonos, Arlan Martin, Lisa McCulloch, Charles Y. Tan   +7 more
doaj   +1 more source

Spectral Efficiency of Mixed-ADC Massive MIMO

, 2018
We study the spectral efficiency (SE) of a mixed-ADC massive MIMO system in which K single-antenna users communicate with a base station (BS) equipped with M antennas connected to N high-resolution ADCs and M-N one-bit ADCs.
Pirzadeh, Hessam, Swindlehurst, A. Lee
core   +1 more source

A 76nW, 4kS/s 10-bit SAR ADC with offset cancellation for biomedical applications [PDF]

, 2016
This paper presents a 10-bit fully-differential rail-to-rail successive approximation (SAR) ADC designed for biomedical applications. The ADC, fabricated in a 180nm HV CMOS technology, features low switching energy consumption and employs a time-domain ...
Carrasco Robles, Manuel, Delgado Restituto, Manuel, Fiorelli, Rafaella, Ginés Arteaga, Antonio José, Rodríguez Vázquez, Ángel Benito   +4 more
core   +1 more source