Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Numerical study of ship motions and added resistance in regular incident waves of KVLCC2 model
International Journal of Naval Architecture and Ocean Engineering, 2017 In this study, the numerical investigation of ship motions and added resistance at constant forward velocity of KVLCC2 model is presented. Finite volume CFD code is used to calculate three dimensional, incompressible, unsteady RANS equations.
Yavuz Hakan Ozdemir, Baris Barlas
doaj +1 more source
Conductance of Tomonaga-Luttinger liquid wires and junctions with resistances
, 2011 We study the effect that resistive regions have on the conductance of a quantum wire with interacting electrons which is connected to Fermi liquid leads. Using the bosonization formalism and a Rayleigh dissipation function to model the power dissipation,
Abhiram Soori +13 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
A note on added resistance for slow ships [PDF]
, 2013 Bingham, Harry B., Amini Afshar, Mostafa
openaire +3 more sources
Role of anisotropy in determining stability of electrodeposition at solid-solid interfaces
, 2017 We investigate the stability of electrodeposition at solid-solid interfaces for materials exhibiting an anisotropic mechanical response. The stability of electrodeposition or resistance to the formation of dendrites is studied within a linear stability ...
Ahmad, Zeeshan +1 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Correlation between the residual resistance ratio and magnetoresistance in MgB2
, 2001 The resistivity and magnetoresistance in the normal state for bulk and thin-film MgB2 with different nominal compositions have been studied systematically.
A. S. Cooper +26 more
core +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Does oscillation size matter? Impact of added resistance on the cerebral pressure-flow Relationship in females and males. [PDF]
Physiol Rep, 2022 Newel KT +4 more
europepmc +1 more source