Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Trends in the selection of insecticide resistance in Anopheles gambiae s.l. mosquitoes in northwest Tanzania during a community randomized trial of longlasting insecticidal nets and indoor residual spraying. [PDF]
, 2014 Anopheles gambiae s.l. (Diptera: Culicidae) in Muleba, Tanzania has developed high levels of resistance to most insecticides currently advocated for malaria control. The kdr mutation has almost reached fixation in An. gambiae s.s. in Muleba.
Wright, A +19 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Added Resistance of an AUV Moving Inside a Water Pipeline Due to Wall Proximity
International Journal of Maritime Technology, 2015 This paper evaluates the added resistance of a torpedo shape AUV, moving inside a water pipeline, due to wall effects within the tube. Today, there are long length pipelines of water or petroleum that need to regular inspection.
Mohammad Moonesun +4 more
doaj
Analysis of Instantaneous Ship Resistance-Increase in Waves with CFD URANS
Polish Maritime ResearchTo comply with the requirements set out by the International Maritime Organization (IMO) for reducing greenhouse gas (GHG) emissions, recent efforts have focused on investigating the parameters that affect the increase in ship resistance, with the aim of
Zeraatgar Hamid +2 more
doaj +1 more source
Comparison of CFD simulations with experimental data for a tanker model advancing in waves
International Journal of Naval Architecture and Ocean Engineering, 2011 In this paper, CFD simulation results for a tanker model are compared with experimental data over a range of wave conditions to verify a capability to predict the sea-keeping performance of practical hull forms. CFD simulations are conducted using WISDAM-
Hideo Orihara
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
On a New Formulation for Wave Added Resistance [PDF]
, 2023 Our objective is to present preliminary calculations using a new formulation for the wave added resistance recently derived by Kashiwagi [1]. This method is based on far-field momentum conservation with the far-field integrals moved to the body using Green’s second identity. An incomplete form of this formulation with body-surface integrals has existed
Amini-Afshar, Mostafa; id_orcid 0000-0001-6941-6117 +2 more
openaire
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Numerical study of ship motions and added resistance in regular incident waves of KVLCC2 model
International Journal of Naval Architecture and Ocean Engineering, 2017 In this study, the numerical investigation of ship motions and added resistance at constant forward velocity of KVLCC2 model is presented. Finite volume CFD code is used to calculate three dimensional, incompressible, unsteady RANS equations.
Yavuz Hakan Ozdemir, Baris Barlas
doaj +1 more source