Results 101 to 110 of about 2,720,797 (300)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Radiation-Induced "Zero-Resistance State" and the Photon Assisted Transport

, 2003
We demonstrate that the radiation induced "zero-resistance state" observed in a two-dimensional electron gas is a result of the non-trivial structure of the density of states of the systems and the photon assisted transport.
A. A. Ignatov, G. D. Mahan, Junren Shi, V.I. Ryzhii, V. V. Pavlovich, X. C. Xie   +5 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Numerical Analysis of Effects of Arms with Different Cross-Sections on Straight-Bladed Vertical Axis Wind Turbine

Energies, 2019
Most vertical axis wind turbines (VAWTs) need arms connecting the blades with the rotational axis. The arms increase the power loss of VAWTs; however, the distribution between the pressure and friction influences and their degrees of influence have not ...
Yutaka Hara, Naoki Horita, Shigeo Yoshida, Hiromichi Akimoto, Takahiro Sumi   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Excess current in point contacts on two-band superconductor MgB$_2$ in magnetic field

, 2004
Series of $I(V)$ characteristic and bias-dependent differential resistance $dV/dI(V)$ for point-contacts on the single crystals of two-band superconductor MgB$_2$ were measured in magnetic field up to 9 T.
Ann, Beloborod'ko, Blonder, Bobrov, Brinkman, Bugoslavsky, Buzea, Choi, Eltsev, Eltsev, Gonnelli, Gonnelli, I.K. Yanson, Koshelev, Lee, Lee, Masui, Mazin, Naidyuk, Naidyuk, O.E. Kvitnitskaya, S. Lee, S. Tajima, Samuely, Szabó, Yanson, Yanson, Yu.G. Naidyuk   +27 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Effect of Graphene on Micro-Structure and Properties of MAO Coating Prepared on Mg-Li Alloy

International Journal of Electrochemical Science, 2017
Ceramic coating modified with graphene was formed on Mg-Li alloy by a micro-arc oxidation process in a graphene powders (GE) added silicate electrolyte. The microstructure, composition, tribological and corrosion behaviors of the coatings were performed.
Fei Chen, Yulin Zhang, You Zhang
doaj   +1 more source

The Quantized Hall Insulator: A New Insulator in Two-Dimensions

, 1998
Quite generally, an insulator is theoretically defined by a vanishing conductivity tensor at the absolute zero of temperature. In classical insulators, such as band insulators, vanishing conductivities lead to diverging resistivities. In other insulators,
A Dykhne, AMM Pruisken, CH Lee, D Shahar, D Shahar, D Shahar, D Shahar, D. C. Tsui, D. Shahar, Don Monroe, E Shimshoni, E Shimshoni, HP Wei, HW Jiang, LP Pryadko, M Hilke, M. Hilke, O Viehweger, RJF Hughes, RL Willett, S Kivelson, S. H. Song, SC Zhang, SV Kravchenko, T Ando, T Sajoto, VJ Goldman, VJ Goldman, Y. H. Xie   +28 more
core   +1 more source