Results 41 to 50 of about 5,652,944 (334)

Dopamine, behavior, and addiction [PDF]

Journal of Biomedical Science, 2021
AbstractAddictive drugs are habit-forming. Addiction is a learned behavior; repeated exposure to addictive drugs can stamp in learning. Dopamine-depleted or dopamine-deleted animals have only unlearned reflexes; they lack learned seeking and learned avoidance.
Roy A. Wise, Chloe J. Jordan
openaire   +3 more sources

Vulnerability for alcohol use disorder after adverse childhood experiences (AUDACE): protocol for a longitudinal fMRI study assessing neuropsychobiological risk factors for relapse

BMJ Open, 2022
Background Adverse childhood experiences (ACE) are common and may predispose affected individuals to various health problems, including alcohol use disorder (AUD).
Falk Kiefer, Cagdas Türkmen, Noah Machunze, Haoye Tan, Sarah Gerhardt, Sabine Vollstädt-Klein   +5 more
doaj   +1 more source

The Psychology of Addictive Smartphone Behavior in Young Adults: Problematic Use, Social Anxiety, and Depressive Stress

Frontiers in Psychiatry, 2020
This review enhances the existing literature on relationships between problematic smartphone use (PSU), psychopathology, addictive personality, and online social engagement as regards young adults, giving attention to predictive determinants of addictive
Aurel Pera
semanticscholar   +1 more source

Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms

Molecules, 2019
Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. In the present work, the authors
Claudia Calpe-López, M. Pilar García-Pardo, Maria A. Aguilar   +2 more
doaj   +1 more source

Chemsex and Mental Health of Men Who Have Sex With Men in Germany

Frontiers in Psychiatry, 2020
Background: Chemsex is defined as using certain substances immediately before or during sexual activities to facilitate, prolong and/or intensify sexual experience, mainly by some communities of men who have sex with men (MSM).
Annette Bohn, Annette Bohn, Annette Bohn, Dirk Sander, Thorsten Köhler, Nico Hees, Nico Hees, Felix Oswald, Norbert Scherbaum, Norbert Scherbaum, Daniel Deimel, Daniel Deimel, Daniel Deimel, Henrike Schecke, Henrike Schecke   +14 more
doaj   +1 more source

Who Was Shopping More During the Spring Lockdown 2020 in Germany?

Frontiers in Psychiatry, 2021
Background: During the lockdown, governmental restrictions resulted in changes to the day-to-day routines of many individuals. Some people appear to cope with stress by panic buying in an attempt to stockpile specific goods, resulting in empty ...
Ekaterini Georgiadou, Anne Koopmann, Anne Koopmann, Astrid Müller, Tagrid Leménager, Tagrid Leménager, Thomas Hillemacher, Thomas Hillemacher, Falk Kiefer, Falk Kiefer   +9 more
doaj   +1 more source

The Economic Approach to Addiction; Why Behavioral Economics is a Pertinent Analytical Framework? [PDF]

Interdisciplinary Studies in the Humanities, 2018
This paper sets out to present a better understanding of the economic approach to the analysis of addictive behavior. Addiction, in accordance with the standard definitions, is a consumption behavior, which follows certain behavioral patterns.
M. Motavaseli, E. Razaghi, M.H. Hadi
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Individual stress reactivity predicts alcohol craving and alcohol consumption in alcohol use disorder in experimental and real-life settings

Translational Psychiatry
Stress- and alcohol cues trigger alcohol craving and alcohol consumption in alcohol use disorder (AUD). However, their interactions on a physiological and psychological level and their effects on daily alcohol craving and alcohol use in real-life ...
Judith Zaiser, Sabine Hoffmann, Sina Zimmermann, Tatjana Gessner, Milena Deck, Nina Kim Bekier, Martin Abel, Philipp Radler, Jens Langejürgen, Bernd Lenz, Sabine Vollstädt-Klein, Jan Stallkamp, Clemens Kirschbaum, Falk Kiefer, Patrick Bach   +14 more
doaj   +1 more source

An Assessment of SBIRT Prescreening and Screening Outcomes by Medical Setting and Administration Methodology

Health Services Research & Managerial Epidemiology, 2015
Background: Screening, brief intervention, and referral to treatment (SBIRT) is an efficacious prevention practice. However, little research has assessed differences in prescreening outcomes between inpatient and outpatient primary care or among ...
Jon Agley PhD, MPH, David W. Crabb MD, Lisa E. Harris MD, Ruth A. Gassman PhD, Steven P. Gerke MD   +4 more
doaj   +1 more source