Results 71 to 80 of about 599,677 (299)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

On null hypotheses in survival analysis

, 2019
The conventional nonparametric tests in survival analysis, such as the log-rank test, assess the null hypothesis that the hazards are equal at all times. However, hazards are hard to interpret causally, and other null hypotheses are more relevant in many
Ryalen, Pål Christie, Røysland, Kjetil, Stensrud, Mats Julius   +2 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Aboveground biomass of mongolian larch (Larix sibiricledeb.) forests in the eurasian region [PDF]

, 2019
We used our database of tree biomass with a number of 433 sample trees of Larix from different ecoregions of Eurasia, involving 61 trees from Mongolia for developing an additive model of biomass tree components.
Chasovskikh, V. P., Danilin, I. М., Osmirko, A. A., Tsepordey, I. S., Tsogt, Z., Usoltsev, V. A.   +5 more
core  

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

A comparative study of two stochastic mode reduction methods

, 2005
We present a comparative study of two methods for the reduction of the dimensionality of a system of ordinary differential equations that exhibits time-scale separation. Both methods lead to a reduced system of stochastic differential equations.
Chorin, Chorin, Chorin, Constantin, Deuflhard, Ellis, Gikhman, Givon, Kantz, Kloeden, Kupferman, Kurtz, Kurtz, Majda, Majda, Majda, Majda, Majda, Mori, Nordholm, Panagiotis Stinis, Papanicolaou, Papanicolaou, Papanicolaou, Papanicolaou, Sanders, Sirovich, Zwanzig   +27 more
core   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Milk yield and milk composition responses to change in predicted net energy and metabolizable protein: a meta-analysis

Animal, 2016
Using a meta-analysis of literature data, this study aimed to quantify the dry matter (DM) intake response to changes in diet composition, and milk responses (yield, milk component yields and milk composition) to changes in dietary net energy for ...
J.B. Daniel, N.C. Friggens, P. Chapoutot, H. Van Laar, D. Sauvant   +4 more
doaj   +1 more source

Entropy: The Markov Ordering Approach

, 2013
The focus of this article is on entropy and Markov processes. We study the properties of functionals which are invariant with respect to monotonic transformations and analyze two invariant "additivity" properties: (i) existence of a monotonic ...
Aczel, Aczél, Alberti, Alberti, Alexander N. Gorban, Bazykin, Boltzmann, Cohen, Cressie, Csiszár, Davis, Dobrushin, Edwards, Esteban, George Judge, Gibbs, Gorban, Gorban, Gorban, Gorban, Gorban, Horn, Kolmogorov, Liese, McGregor, Mittelhammer, Pavel A. Gorban, Read, Rockafellar, Rényi, Seneta, Sigmung, Villani, Yablonskii, Zeldovich, Öttinger   +35 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source