Results 141 to 150 of about 13,595 (304)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Some quaternary additive codes outperform linear counterparts

, 2023
The additive codes may have better parameters than linear codes. However, it is still a challenging problem to efficiently construct additive codes that outperform linear codes, especially those with greater distances than linear codes of the same ...
Li, Ruihu, Ma, Zhi, Guan, Chaofeng, Liu, Yiting   +3 more
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Foundations of additive codes over finite fields [PDF]

Altres ajuts: acords transformatius de la UABAdditive codes were initially introduced by Delsarte in 1973 within the context of association schemes and recently they have become of interest due to their application in constructing quantum error ...
Fernández Córdoba, Cristina, Dougherty, Steven T., Villanueva, M, Bhunia, Dipak Kumar   +3 more
core   +1 more source

A Toolpath Generator Based on Signed Distance Fields and Clustering Algorithms for Optimized Additive Manufacturing

Journal of Manufacturing and Materials Processing
Additive manufacturing (AM) methods have been gaining momentum because they provide vast design and fabrication possibilities, increasing the accessibility of state-of-the-art hardware through recent developments in user-friendly computer-aided drawing ...
Alp Karakoç
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and Implementation of a Fast Gaussian Noise Generator

, 2007
In modern communication systems, powerful error control codes such as Turbo code and Low-Density Parity Check (LDPC) codes are employed to provide capacity approaching coding gains. Both of these codes have very low bit error rate.
王仁傑, Wang, Jen-Chieh
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Research on the Lightweight Design of Aviation Generator Rear Cover Utilizing Topology Optimization

Applied Sciences
Topology optimization serves as a critical method for promoting lightweight structural design. Traditional methods predominantly focus on mechanical performance evaluation, often neglecting the critical correlation between modal characteristics and ...
Huazhong Zhang, Hongbiao Yin, Xu Deng, Hengxin Xu, Zhigang Yao   +4 more
doaj   +1 more source