Results 131 to 140 of about 149 (149)
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Mercapturic Acids, Protein Adducts, and DNA Adducts as Biomarkers of Electrophilic Chemicals
Critical Reviews in Toxicology, 1992The possibilities and limitations of using mercapturic acids and protein and DNA adducts for the assessment of internal and effective doses of electrophilic chemicals are reviewed. Electrophilic chemicals may be considered as potential mutagens and/or carcinogens.
R. T. H. van Welie +3 more
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Alkali metal adducts of benzophenone azine. II. The lithium adduct
Canadian Journal of Chemistry, 1970The behavior of benzophenone azine towards lithium has been studied. Unlike sodium and potassium, lithium effected extensive reduction and cleavage of benzophenone azine; the reaction product being benzhydryl amine. By limiting the amount of lithium to 2 g-atoms per mole of azine, the reaction product was shown to be N-lithiobenzophenone imine on the ...
E. J. MacPherson, James G. Smith
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Electrosynthesis of cyclopropanone adducts
Recueil des Travaux Chimiques des Pays-Bas, 1980AbstractElectroreduction of α,α′‐dihalo ketones to cyclopropanones (isolated as the hemiacetals or hemiacylals) is accomplished with good yields only with highly alkylated α,α′‐dihalo ketones. Attempts to prepare little substituted or unsubstituted cyclopropanone (derivatives) by electroreduction of α,α′‐dihalo ketones in which the carbonyl group is ...
R. Plomp +3 more
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Carcinogenesis, 1991
The action of DNA polymerase (Sequenase Version 2.0) on an oligonucleotide template containing a 7-bromomethyl-benz[a]anthracene-deoxyadenosine adduct flanked by thymidine residues was investigated. The polymerase incorporated deoxyadenosine or deoxyguanosine residues opposite the thymidine 3' to the adduct with similar efficiencies. Whereas the normal
Andrew M. Hruszkewycz, Anthony Dipple
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The action of DNA polymerase (Sequenase Version 2.0) on an oligonucleotide template containing a 7-bromomethyl-benz[a]anthracene-deoxyadenosine adduct flanked by thymidine residues was investigated. The polymerase incorporated deoxyadenosine or deoxyguanosine residues opposite the thymidine 3' to the adduct with similar efficiencies. Whereas the normal
Andrew M. Hruszkewycz, Anthony Dipple
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Cyclic Silylhydrazines and Their Borane Adducts
Inorganic Chemistry, 1995A series of five-, six-, and seven-membered cyclic silylhydrazines have been prepared from the reactions of 1,2-bis(bromosilyl)ethane and 1,3-bis(bromosilyl)propane with 1,1-dimethylhydrazine [leading to 1-(dimethylamino)-1-aza-2,5-disilacyclopentane (3) and 1-(dimethylamino)-1-aza-2,6-disilacyclohexane (4)] and 1,2-dimethylhydrazine [leading to 1,2 ...
Mitzel, Norbert W. +5 more
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ChemInform Abstract: ADDUCTS OF TETRACHLOROBENZYNE AND PYRROLES
Chemischer Informationsdienst, 1976AbstractDas aus Hexachlorbenzol (I) mit n‐Butyllithium hergestellte Tetrachlordehydrobenzol (II) ergibt mit den Pyrrolen (III) die Cycloaddukte (IV) und mit (IIIb) zusätzlich in geringer Menge das Cyclobutenderivat (Vb).
Munir Ahmed, John M. Vernon
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Amide-Adducts in Atherosclerosis
2013Too many hypotheses in the etiology of atherosclerosis have been proposed. Classically, lipid insudation hypothesis by Virchow and thrombogenic hypothesis by Rokitansky are famous. However, in the recent progress in the area of atherosclerosis, the response-to-injury hypothesis by Ross (Ross R Glomset JA, N Engl J Med 295:369-377, 420-425, 1976; Ross R,
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Chemical Research in Toxicology, 1992
Crotonaldehyde, a chemically reactive alpha,beta-unsaturated carbonyl compound, is an important industrial chemical and a ubiquitous environmental pollutant. It has been shown to be carcinogenic and mutagenic. We have studied the reaction of crotonaldehyde with nucleosides and 5'-mononucleotides and found three different types of adducts with ...
Erwin Eder, Christian Hoffman
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Crotonaldehyde, a chemically reactive alpha,beta-unsaturated carbonyl compound, is an important industrial chemical and a ubiquitous environmental pollutant. It has been shown to be carcinogenic and mutagenic. We have studied the reaction of crotonaldehyde with nucleosides and 5'-mononucleotides and found three different types of adducts with ...
Erwin Eder, Christian Hoffman
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1994
Publisher Summary Redox active metal ions, such as iron and copper play a central role in the formation of reactive oxygen species in biological systems. Although iron has received the most attention in this capacity, the role of copper may be particularly crucial because copper occurs naturally in chromosomes, where it is believed to play a role in ...
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Publisher Summary Redox active metal ions, such as iron and copper play a central role in the formation of reactive oxygen species in biological systems. Although iron has received the most attention in this capacity, the role of copper may be particularly crucial because copper occurs naturally in chromosomes, where it is believed to play a role in ...
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Adduct Formation of OH With Benzene and Toluene and Reaction of the Adducts with NO and NO2
1990The behaviour of the adducts of OH with the aromatics benzene and toluene has been studied at 130 mbar in Ar in the presence of NO and NO2 at four temperatures in the range from 300 to 350K. Biexponential decays of OH are observed in the absence of NOx and in the presence of NO. After eliminating NO2 impurities from the NO sample, the reactivity of the
Franz Witte +4 more
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