Results 251 to 260 of about 198,348 (348)

Unified Deep Learning of Molecular and Protein Language Representations with T5ProtChem. [PDF]

J Chem Inf Model
Kelly T, Xia S, Lu J, Zhang Y.
europepmc   +1 more source

Synthetic study of amino-sugars from pyridines. IV. Synthesis of 5-amino-5-deoxypiperidinoses from the singlet oxygen adduct of 1-acyl-1,2-dihydropyridines.

, 1978
Mitsutaka Natsume, YASUO SEKINE, Hiroe Soyagimi   +2 more
openalex   +2 more sources

Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions

Angewandte Chemie, EarlyView.
In this study, we capitalize on the versatility offered by genetic code expansion to develop a proficient photoenzyme for [2 + 2]‐cycloadditions that is enantiocomplementary to our recently developed photoenzyme EnT1.3. By repositioning the genetically programmed benzophenone photosensitizer and subsequent directed evolution, we have developed an ...
Chuanjie Sun, Anna R. Kohn, Ross Smithson, Florence J. Hardy, Jonathan S. Trimble, Yuanxin Cao, Linus O. Johannissen, Sam Hay, Rebecca Crawshaw, Anthony P. Green   +9 more
wiley   +1 more source

MS1FA: Shiny app for the annotation of redundant features in untargeted metabolomics datasets. [PDF]

Bioinformatics
Shi R, Klawonn F, Brönstrup M, Franke R.   +3 more
europepmc   +1 more source

Structural Insight Into a Human H Ferritin@Gold‐Monocarbene Adduct: Aurophilicity Revealed in a Biological Context

Angewandte Chemie, EarlyView.
Human H ferritin (HuHf) is a nanocarrier for anticancer metal drugs. By cryo‐EM, a 1.51 Å structure of its adduct with Au(NHC)Cl was solved, showing a novel tetranuclear gold(I) cluster bound to Cys90 and Cys102. Short inter‐metal distances indicate aurophilic interactions.
Lucrezia Cosottini, Andrea Giachetti, Annalisa Guerri, Ane Martinez‐Castillo, Andrea Geri, Stefano Zineddu, Nicola G. A. Abrescia, Luigi Messori, Paola Turano, Antonio Rosato   +9 more
wiley   +1 more source

Photoredox/Nickel-Catalyzed Diastereoselective Allylation of Aldehydes with Morita-Baylis-Hillman Adducts. [PDF]

ACS Catal
Calogero F, Pinosa E, Gualandi A, Sensoli L, Dutta S, Maity B, Cavallo L, Fermi A, Ceroni P, Cozzi PG.   +9 more
europepmc   +1 more source

Mechanoactivated Celite as a Catalyst for C‒H Bond Perfluoroalkylation and Other Radical Reactions

Angewandte Chemie, EarlyView.
Biogenic materials naturally containing trace metals such as Celite or diatomaceous earth promote practical perfluoroalkylation of C─H bonds of (hetero)arenes and a double bond bromination with N‐bromosuccinimide upon mechanoactivation via ball milling. This conceptually broadens the scope of mechanoactivated solids beyond piezoelectric materials. This
Thomas J. Hasiweder, Hoan M. Dinh, Dilip K. Pandey, Aleksandr Sorvanov, Julia R. Khusnutdinova   +4 more
wiley   +1 more source

Planarity Is Not Plain: Closed- vs Open-Shell Reactivity of a Structurally Constrained, Doubly Reduced Arylborane toward Fluorobenzenes. [PDF]

J Am Chem Soc
Buch CD, Virovets A, Peresypkina E, Endeward B, Lerner HW, Fantuzzi F, Yamaguchi S, Wagner M.   +7 more
europepmc   +1 more source

Thiotemplated Polyketide Chain Fusion and Reductive Cyclization Build the Reactive Butenolide Core of Malleicyprol

Angewandte Chemie, EarlyView.
Malleicyprol, a virulence factor of notorious animal and human pathogens of the Burkholderia pseudomallei (BP) group, results from the fusion of two individual polyketide chains. The noncanonical condensation domain of the PKS–NRPS hybrid synthetase BurF forms an ester bond, and the terminal reductase domain mediates a reductive chain release followed ...
Jonas Fiedler, Leo Dumjahn, Mie Ishida‐Ito, Felix Trottmann, Keishi Ishida, Christian Hertweck   +5 more
wiley   +1 more source

N‐Insertion of Diazonium Salts Into Ketone Derivatives

Angewandte Chemie, EarlyView.
Diazonium salts insert into ketones and their silyl enol ethers through a sequence of α‐azenylation and ring expansion via an N‐iminoaziridinium species. Coupled with an efficient N‐N bond cleavage, this protocol offers a mild alternative to Beckmann rearrangements and a powerful tool for skeletal editing of ketones.
Mohammed Anif Pasha, Jiwon Jang, Youngjin Bae, Seunghoon Shin   +3 more
wiley   +1 more source