Results 251 to 260 of about 207,770 (335)

From Pharmacophore to Warhead: NAD⁺-Targeting Triazoles as Mechanism-Based Sirtuin Inhibitors. [PDF]

Angew Chem Int Ed Engl
Friedrich F, Meleshin M, Papenkordt N, Gaitzsch L, Prucker I, Borso M, Ruprecht J, Vorreiter C, Rast S, Zhang L, Schiedel M, Sippl W, Imhof A, Jessen HJ, Einsle O, Schutkowski M, Jung M.   +16 more
europepmc   +1 more source

Acid‐ and Nucleophile‐Gated Photoisomerization of Phosphaindirubin

Angewandte Chemie, EarlyView.
Triply gated isomerization: In polar solvents, a phosphorus‐containing indirubin photoswitch undergoes visible‐light‐driven Z→E isomerization only when protonated, and reverts thermally via nucleophile‐catalyzed back‐isomerization. This three‐way control by light, acid, and nucleophile enables reversible photoisomerization.
Jacob Jan van der Wal, Jorn D. Steen, Ann‐Kathrin Rückert, Roman Yu. Peshkov, Michiel F. Hilbers, P. Tim Prins, Wybren Jan Buma, Andreas Orthaber, Stefano Crespi   +8 more
wiley   +1 more source

Exploring non-covalent interactions in binary aromatic complexes.

CrystEngComm
Bear JC, Cockcroft JK, Rosu-Finsen A, Williams JH.   +3 more
europepmc   +1 more source

Long-Patch Base Excision Repair of 5'-DNA-Peptide Cross-Links Derived from Abasic DNA Lesions. [PDF]

Biochemistry
Bryan C, Cepeda J, Wei X, Yang K.
europepmc   +1 more source

Monitoring Occupational Exposure to Ethylene Oxide by the Determination of Hemoglobin Adducts

, 1993
Nico J. van Sittert, Gerard D. J. Beulink, Erik W. N. van Vliet, Henk van der Waal   +3 more
openalex   +1 more source

Chemical Proteomics Identifies Ketogenesis‐Mediated Cysteine Modifications Regulating Redox Function

Angewandte Chemie, EarlyView.
Herein, we report ketone body induce cysteine modifications beyond lysine acylation, as revealed by integrating chemical proteomics with open‐search methods. Among the modifications, cysteine crotonation (Ccr) was chemically validated by endogenous peptide‐based co‐elution assays.
Yuan‐Fei Zhou, Ling Zhang, Zhuoyi L. Niu, Xin Wang, Alejandro Storper, Ryan Hunt, Yingming Zhao, Nima Sharifi, Zhipeng A. Wang   +8 more
wiley   +1 more source

MetScribeR: A Semiautomated Tool for Data Processing of In-House LC-MS Metabolite Reference Libraries. [PDF]

J Proteome Res
Tisch AM, Inman JM, Mathé EA, Bennouna D.   +3 more
europepmc   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, EarlyView.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +1 more source

Signal propagation in LOV-based multidomain proteins: time-resolved infrared spectroscopy reveals the complete photocycle of YF1 and PAL.

Phys Chem Chem Phys
Herzog RE, Janke P, Fischer PM, Heckmeier PJ, Wei C, Nag P, Hartmann SJ, Mulder M, Stierli F, Standfuss J, Schapiro I, Hamm P.   +11 more
europepmc   +1 more source

Observation of shuttling on the one-second timescale in a [10]cycloparaphenylene/C₆₀ [2]catenane. [PDF]

Chem Sci
Steudel FM, Sabrià C, Piane MD, Feixas F, Ribas X, Pavan GM, von Delius M.   +6 more
europepmc   +1 more source