Results 321 to 330 of about 198,348 (348)

Mercapturic Acids, Protein Adducts, and DNA Adducts as Biomarkers of Electrophilic Chemicals

Critical Reviews in Toxicology, 1992
The possibilities and limitations of using mercapturic acids and protein and DNA adducts for the assessment of internal and effective doses of electrophilic chemicals are reviewed. Electrophilic chemicals may be considered as potential mutagens and/or carcinogens.
R. T. H. van Welie, R. G. J. M. Van Dijck, N. J. Van Sittert, Nico P. E. Vermeulen   +3 more
openaire   +3 more sources

Electrosynthesis of cyclopropanone adducts

Recueil des Travaux Chimiques des Pays-Bas, 1980
AbstractElectroreduction of α,α′‐dihalo ketones to cyclopropanones (isolated as the hemiacetals or hemiacylals) is accomplished with good yields only with highly alkylated α,α′‐dihalo ketones. Attempts to prepare little substituted or unsubstituted cyclopropanone (derivatives) by electroreduction of α,α′‐dihalo ketones in which the carbonyl group is ...
R. Plomp, W. J. M. Van Tilborg, R. De Ruiter, Cornelis Jacobus Smit   +3 more
openaire   +3 more sources

Bypass of a hydrocarbon adduct in an oligonucleotide template mediated by mispairing adjacent to the adduct

Carcinogenesis, 1991
The action of DNA polymerase (Sequenase Version 2.0) on an oligonucleotide template containing a 7-bromomethyl-benz[a]anthracene-deoxyadenosine adduct flanked by thymidine residues was investigated. The polymerase incorporated deoxyadenosine or deoxyguanosine residues opposite the thymidine 3' to the adduct with similar efficiencies. Whereas the normal
Andrew M. Hruszkewycz, Anthony Dipple
openaire   +3 more sources

Di(4-methylphenyl)methano-C60 Bis-Adduct for Efficient and Stable Organic Photovoltaics with Enhanced Open-Circuit Voltage

, 2011
A new class of fullerene bis-adducts—di(4-methylphenyl)methano-C60 bis-adduct (DMPCBA), di(4-fluorophenyl)methano-C60 bis-adduct (DFPCBA), and diphenylmethano-C60 bis-adduct (DPCBA)—were rationally designed and easily synthesized.
Yen‐Ju Cheng, Ming-Hung Liao, C. Chang, W. Kao, Cheng-en Wu, Chain‐Shu Hsu   +5 more
semanticscholar   +1 more source

Alkali metal adducts of benzophenone azine. II. The lithium adduct

Canadian Journal of Chemistry, 1970
The behavior of benzophenone azine towards lithium has been studied. Unlike sodium and potassium, lithium effected extensive reduction and cleavage of benzophenone azine; the reaction product being benzhydryl amine. By limiting the amount of lithium to 2 g-atoms per mole of azine, the reaction product was shown to be N-lithiobenzophenone imine on the ...
E. J. MacPherson, James G. Smith
openaire   +2 more sources

Analysis of acrylamide, a carcinogen formed in heated foodstuffs.

Journal of Agricultural and Food Chemistry, 2002
Reaction products (adducts) of acrylamide with N termini of hemoglobin (Hb) are regularly observed in persons without known exposure. The average Hb adduct level measured in Swedish adults is preliminarily estimated to correspond to a daily intake ...
E. Tareke, P. Rydberg, P. Karlsson, S. Eriksson, M. Törnqvist   +4 more
semanticscholar   +1 more source

Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation.

Free Radical Research Communications, 1986
DNA or 2-deoxyguanosine reacts with hydroxyl free radical to form 8-hydroxy-deoxyguanosine (8-OH-dG). We found that 8-OH-dG can be effectively separated from deoxyguanosine by high pressure liquid chromatography and very sensitively detected using ...
R. Floyd, J. Watson, P. K. Wong, D. Altmiller, R. C. Rickard   +4 more
semanticscholar   +1 more source

ChemInform Abstract: ADDUCTS OF TETRACHLOROBENZYNE AND PYRROLES

Chemischer Informationsdienst, 1976
AbstractDas aus Hexachlorbenzol (I) mit n‐Butyllithium hergestellte Tetrachlordehydrobenzol (II) ergibt mit den Pyrrolen (III) die Cycloaddukte (IV) und mit (IIIb) zusätzlich in geringer Menge das Cyclobutenderivat (Vb).
Munir Ahmed, John M. Vernon
openaire   +3 more sources

Facile Synthesis of a Rare Chlorosilylene–BH3 Adduct

, 2011
The first stable chlorosilylene–BH3 adduct was synthesized in the reaction of N-heterocyclic carbene (NHC) stabilized dichlorosilylene either with equivalent amounts of LiBH4 or with equivalent amounts of a BH3·THF solution. The chlorosilylene–BH3 adduct
R. Azhakar, G. Tavčar, H. Roesky, J. Hey, D. Stalke   +4 more
semanticscholar   +1 more source

Cyclic Silylhydrazines and Their Borane Adducts

Inorganic Chemistry, 1995
A series of five-, six-, and seven-membered cyclic silylhydrazines have been prepared from the reactions of 1,2-bis(bromosilyl)ethane and 1,3-bis(bromosilyl)propane with 1,1-dimethylhydrazine [leading to 1-(dimethylamino)-1-aza-2,5-disilacyclopentane (3) and 1-(dimethylamino)-1-aza-2,6-disilacyclohexane (4)] and 1,2-dimethylhydrazine [leading to 1,2 ...
Mitzel, Norbert W., HOFMANN, M, ANGERMAIER, K, SCHIER, A, SCHLEYER, PV, SCHMIDBAUR, H   +5 more
openaire   +1 more source