Results 41 to 50 of about 198,348 (348)

Titanium dioxide nanoparticles induce oxidative stress and DNA-adduct formation but not DNA-breakage in human lung cells

open access: yesParticle and Fibre Toxicology, 2009
Titanium dioxide (TiO2), also known as titanium (IV) oxide or anatase, is the naturally occurring oxide of titanium. It is also one of the most commercially used form.
K. Bhattacharya   +5 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

open access: yesAdvanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Acetonitrile Adducts of Tranexamic Acid as Sensitive Ions for Quantification at Residue Levels in Human Plasma by UHPLC-MS/MS

open access: yesPharmaceuticals, 2021
The quantitative analysis of pharmaceuticals in biomatrices by liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) is often hampered by adduct formation.
Eduarda M. P. Silva   +5 more
doaj   +1 more source

Self‐Cascade Catalytic Reaction–Assisted Apoptosis/Calcicoptosis/Ferroptosis Induction with Microsphere‐Aggregated Hydrogels in Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang   +6 more
wiley   +1 more source

Making Photoresponsive Metal–Organic Frameworks an Effective Class of Heterogeneous Photocatalyst

open access: yesAdvanced Functional Materials, EarlyView.
This review summarizes photoresponsive MOFs for photocatalytic applications, focusing on their capacity to enhance light harvesting, charge transfer, and surface reactions. While existing studies provide foundational insights, emerging characterization techniques enable a deeper understanding of photoresponsive MOFs.
Rui Liu   +3 more
wiley   +1 more source

Detection of busulfan adducts on proteins

open access: yesRapid Communications in Mass Spectrometry, 2016
RationaleBusulfan is a bifunctional alkyl sulfonate antineoplastic drug. This alkylating agent was described as forming covalent adducts on proteins. However, only limited data are available regarding the interaction of busulfan with proteins. Mass spectrometry and bioinformatics were used to identify busulfan adducts on human serum albumin and ...
Marc Ansari   +10 more
openaire   +4 more sources

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

open access: yesAdvanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou   +2 more
wiley   +1 more source

DNA adducts-chemical addons

open access: yesJournal of Pharmacy And Bioallied Sciences, 2015
DNA adduct is a piece of DNA covalently bond to a chemical (safrole, benzopyrenediol epoxide, acetaldehyde). This process could be the start of a cancerous cell. When a chemical binds to DNA, it gets damaged resulting in abnormal replication. This could be the start of a mutation and without proper DNA repair, this can lead to cancer.
T R Rajalakshmi   +3 more
openaire   +4 more sources

Engineering Strategies for 2D Layered Tin Halide Perovskite Field‐Effect Transistors

open access: yesAdvanced Functional Materials, EarlyView.
2D halide perovskites are promising candidates for field‐effect transistor (FET) applications due to their high stability and suppressed ion migration in the presence of bulky organic spacers. This review systematically summarizes the optimization engineering strategies of 2D perovskite FETs and future challenges, which provide guidance for developing ...
Shuanglong Wang   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy