Results 41 to 50 of about 207,770 (335)
Crystal structure of 4-aminobenzoic acid–4-methylpyridine (1/1)
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title 1:1 adduct, C6H7N·C7H7NO2, the carboxylic acid group is twisted at an angle of 4.32 (18)° with respect to the attached benzene ring. In the crystal, the carboxylic acid group is linked to the pyridine ring by an O—H...N hydrogen bond ...
M. Krishna Kumar +4 more
doaj +1 more source
Solvation agent for disulfide precipitates from inhibited glycol-water solutions [PDF]
, 1971 Small additions /0.01 percent or less/ of triethanoloamine sodium sulfite adduct to mercapto benzothiazole inhibited glycol water heat transfer solutions containing disulfide precipitate produce marked reduction in amount of precipitate. Adduct is useful
Taylor, M. F.
core +1 more source
The role of the mobile proton in fucose migration [PDF]
, 2019 Fucose migration reactions represent a substantial challenge in the analysis of fucosylated glycan structures by mass spectrometry. In addition to the well-established observation of transposed fucose residues in glycan-dissociation product ions, recent ...
Helden, Gert von +7 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Why is Aged Acetylcholinesterase So Difficult to Reactivate?
Molecules, 2017 Organophosphorus agents are potent inhibitors of acetylcholinesterase. Inhibition involves successive chemical events. The first is phosphylation of the active site serine to produce a neutral adduct, which is a close structural analog of the acylation ...
Daniel M. Quinn +3 more
doaj +1 more source
SYNTESIS AND CRYSTALLINE STRUCTURE OF THE EXO-3,6-DIMETHYL-3,6-EPOXI-1,2,3,6-TETRAHYDROPHTLALIMIDE AND ITS N-BROMODECYL ANALOG: TWO THERMALLY LABILE DIELS-ALDER ADDUCTS [PDF]
, 2014 Indexación: Web of Science; Scielo.The molecular structure of the exo-3,6-dimethyl-3,6-epoxi-1,2,3,6-tetrahydrophthalimide (1), determined by X-ray diffraction analysis, as well as, its complete spectroscopic characterization and the synthesis and ...
ARAYA-FUENTES, EYLEEN +4 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Trialkylborane-Assisted CO_2 Reduction by Late Transition Metal Hydrides [PDF]
, 2011 Trialkylborane additives promote reduction of CO_2 to formate by bis(diphosphine) Ni(II) and Rh(III) hydride complexes. The late transition metal hydrides, which can be formed from dihydrogen, transfer hydride to CO_2 to give a formateborane adduct.
Bercaw, John E. +2 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Pharmaceuticals, 2021 The quantitative analysis of pharmaceuticals in biomatrices by liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) is often hampered by adduct formation.
Eduarda M. P. Silva +5 more
doaj +1 more source