Results 11 to 20 of about 1,901 (143)

Liquid-Assisted Grinding to Prepare a Cocrystal of Adefovir Dipivoxil Thermodynamically Less Stable than Its Neat Phase

Crystals, 2015
Liquid-assisted grinding was employed to generate a cocrystal of adefovir dipivoxil (AD) and glutaric acid (GLU), which had not been successfully obtained through solution crystallization.
Il Won Kim, Sungyup Jung, Kim Il Won
exaly   +3 more sources

Efficacy of nucleos(t)ide analogues(NAs) in preventing virus reactivation in oncology patients with HBV infection after chemotherapy or surgery: A network meta-analysis

Frontiers in Oncology, 2023
ObjectiveIn this study, we aimed to perform a network meta-analysis to compare the effectiveness of NAs in decreasing the reactivation of HBV, reducing chemotherapy disruption, and improving survival in oncology patients.MethodsRelevant randomized ...
Yuqing Zhao, Yuqing Zhao, Yingying Song, Huan Zhang, Huan Zhang, Tongshuo Qu, Tongshuo Qu, Malina Axinbai, Malina Axinbai, Yidian Yang, Yidian Yang, Liping Zhang, Liping Zhang   +12 more
doaj   +1 more source

Pathological Femoral Fracture due to Osteoporosis and Hypophosphatemic Osteomalacia Following Adefovir Therapy in a Patient with Chronic Hepatitis B [PDF]

Türk Osteoporoz Dergisi, 2018
Adefovir dipivoxil (ADV) is a nucleotide analogue used in the chronic hepatitis B treatment. Proximal renal tubular dysfunction is one of the adverse effects of this agent and characterized with hypophosphatemia and osteomalacia.
Sevilay Batıbay, Duygu Geler Külcü, Nilgün Mesci, Borçak Çağlar Ruhi, Zerrin Şahin, Hasan Gündoğdu   +5 more
doaj   +1 more source

Drug Discovery of Nucleos(t)ide Antiviral Agents: Dedicated to Prof. Dr. Erik De Clercq on Occasion of His 80th Birthday

Molecules, 2021
Nucleoside and nucleotide analogues are essential antivirals in the treatment of infectious diseases such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), herpes simplex virus (HSV), varicella-zoster virus (VZV ...
Guangdi Li, Tingting Yue, Pan Zhang, Weijie Gu, Ling-Jie Gao, Li Tan   +5 more
doaj   +1 more source

Denosumab improves clinical manifestations of hypophosphatemic osteomalacia by adefovir-induced Fanconi syndrome: a case report

Journal of Medical Case Reports, 2019
Background Adefovir dipivoxil is a nucleotide analogue that is approved for treatment of chronic hepatitis B. Adefovir dipivoxil is associated with proximal tubular dysfunction, resulting in Fanconi syndrome, which can cause secondary hypophosphatemic ...
Tomohisa Kunii, Toshie Iijima, Teruo Jojima, Masanori Shimizu, Masato Kase, Shintaro Sakurai, Takahiko Kogai, Isao Usui, Yoshimasa Aso   +8 more
doaj   +1 more source

Evaluation of Ion-pair Formation of Adefovir to Improve Permeation across Artificial and Biological Membranes

Journal of Pharmacy & Pharmaceutical Sciences, 2018
Purpose: Adefovir is an antiviral drug that exhibits high hydrophilic properties and negligible bioavailability (less than 12%). It is only applied in the form of the ester prodrug adefovir dipivoxil (ADV). The oral bioavailability of ADV is limited (32%
Bahar Darsazan, Alireza Shafaati, Afshin Zarghi, Seyed Alireza Mortazavi   +3 more
doaj   +1 more source

Th1 and Th2 Immune Response in Chronic Hepatitis B Patients during a Long-Term Treatment with Adefovir Dipivoxil

Mediators of Inflammation, 2010
Adefovir dipivoxil treatment has significantly improved the outcome of chronic hepatitis B virus (HBV) infection. However, it remains largely unknown how immune system responds to the treatment.
Yanfang Jiang, Zhenhua Ma, Guijie Xin, Hongqing Yan, Wanyu Li, Huining Xu, Chunhai Hao, Junqi Niu, Pingwei Zhao   +8 more
doaj   +1 more source

Tenofovir Alafenamide Rescues Renal Tubules in Patients with Chronic Hepatitis B

Life, 2021
Nucles(t)ide analogs (NAs) are effective for chronic hepatitis B (CHB). NAs suppress hepatic decompensation and hepatocarcinogenesis, leading to a dramatic improvement of the natural course of patients with CHB.
Tomoya Sano, Takumi Kawaguchi, Tatsuya Ide, Keisuke Amano, Reiichiro Kuwahara, Teruko Arinaga-Hino, Takuji Torimura   +6 more
doaj   +1 more source

Use of eosin for spectroscopic determination of Adefovir dipivoxil [PDF]

Records of Pharmaceutical & Biomedical Sciences
This paper elucidates a new spectrofluorometric method for the determination of Adefovir Dipivoxil in its pharmaceutical dosage form using Eosin, the colored ion - pair complex was produced at λ em 544 nm and excitation at λ ex 267 in acetate buffer ...
ElSayed Ibrahim, Shaimaa Elsayed, Alaa El-Gendy, Yasser El-shabrawy   +3 more
doaj   +1 more source

Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report

Diagnostic Pathology, 2012
We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia.
Tanaka Motoyuki, Setoguchi Takao, Ishidou Yasuhiro, Arishima Yoshiya, Hirotsu Masataka, Saitoh Yoshinobu, Nakamura Shunsuke, Kakoi Hironori, Nagano Satoshi, Yokouchi Masahiro, Kamizono Junichi, Komiya Setsuro   +11 more
doaj   +1 more source