Results 1 to 10 of about 489,286 (375)

Simplified adenine base editors improve adenine base editing efficiency in rice

open access: yesPlant Biotechnology Journal, 2019
Summary Adenine base editors (ABEs) have been exploited to introduce targeted adenine (A) to guanine (G) base conversions in various plant genomes, including rice, wheat and Arabidopsis.
Kai Hua   +5 more
semanticscholar   +1 more source

N6,9-BIS(FERROCENYLMETHYL)ADENINE: SYNTHESIS, CYCLIC VOLTAMMETRIC, SPECTROSCOPIC CHARACTERIZATION, AND DFT CALCULATIONS

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2019
n this paper we investigate the synthesis of N6,9-bis(ferrocenylmethyl)adenine starting from the well known quaternary salt (ferrocenylmethy)trimethylammonium iodide and adenine.
ELHAFNAOUI LANEZ   +2 more
doaj  

Biological roles of adenine methylation in RNA

open access: yesNature reviews genetics, 2022
Konstantinos Boulias, E. L. Greer
semanticscholar   +1 more source

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

open access: yeseLife, 2018
Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (NMN),
Antonio Davila   +9 more
semanticscholar   +1 more source

Fox grape cv. Bordô (Vitis labrusca L.) and grapevine cv. Chardonnay (Vitis vinifera L.) cultivated in vitro under different carbohydrates, amino acids and 6-Benzylaminopurine levels

open access: yesBrazilian Archives of Biology and Technology, 2013
The aim of this work was to study the influence of sucrose and glucose, amino acids and BAP (6-Benzylaminopurine) levels on in vitro shoot regeneration of fox grape cv. Bordô and grapevine cv. Chardonnay.
Dayse Cristina de Carvalho   +5 more
doaj  

Effects of the SGLT-2 Inhibitor Canagliflozin on Adenine-Induced Chronic Kidney Disease in Rats.

open access: yesCellular Physiology and Biochemistry, 2019
BACKGROUND/AIMS SGLT-2 inhibitors have been shown to be nephroprotective in diabetes. Here, we examined if one of these drugs (canagliflozin) could also ameliorate non-diabetic chronic kidney disease (CKD).
B. Ali   +10 more
semanticscholar   +1 more source

Insight into G-quadruplex-hemin DNAzyme/RNAzyme: adjacent adenine as the intramolecular species for remarkable enhancement of enzymatic activity

open access: yesNucleic Acids Research, 2016
G-quadruplex (G4) with stacked G-tetrads structure is able to bind hemin (iron (III)-protoporphyrin IX) to form a unique type of DNAzyme/RNAzyme with peroxidase-mimicking activity, which has been widely employed in multidisciplinary fields.
Wang Li   +7 more
semanticscholar   +1 more source

Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program [PDF]

open access: yes, 2018
The Schwann cell (SC) is the major component of the peripheral nervous system (PNS) that provides metabolic and functional support for peripheral axons. The emerging roles of SC mitochondrial function for PNS development and axonal stability indicate the
Hackett, Amber R   +4 more
core   +1 more source

Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation

open access: yesNature Communications, 2019
The extension of the amyloid hypothesis to include non-protein metabolite assemblies invokes a paradigm for the pathology of inborn error of metabolism disorders.
Dana Laor   +12 more
semanticscholar   +1 more source

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