Therapeutic potential of L-Carnitine in improving adenine-induced hematological abnormalities in rats: A preclinical pharmacological study [PDF]
Open Veterinary JournalBackground: Adenine is a naturally occurring purine essential for life, but its excess intake can cause metabolic disturbances leading to cardiovascular complications, renal stones, gout, fatigue, and anemia.
Waleed Khaled Y. Albahadly +4 more
doaj +2 more sources
Construction and Anti-Cancer Activity of a Self-Assembly Composite Nano-Delivery System Loaded with Curcumin [PDF]
MoleculesNatural products possess potent pharmacological activities and health benefits. However, drawbacks such as water insolubility, poor stability, and low bioavailability limit their practical applications.
Liang Chen +6 more
doaj +2 more sources
Effect of fetuin-A on adenine-induced chronic kidney disease model in male rats [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): This study aimed to investigate the possible effects of fetuin-A on an adenine-induced chronic kidney disease (CKD) model in male rats.
Wesam Ashour +3 more
doaj +1 more source
Frontiers in Pharmacology, 2022 CKD is a clinical syndrome with slow development and gradual deterioration of renal function. At present, modern medicine still lacks an ideal treatment method for this disease, while TCM has accumulated rich clinical experience in the treatment of CKD ...
Ling Wang +10 more
doaj +1 more source
The Non-Equilibrium Thermodynamics of Natural Selection: From Molecules to the Biosphere
Entropy, 2023 Evolutionary theory suggests that the origin, persistence, and evolution of biology is driven by the “natural selection” of characteristics improving the differential reproductive success of the organism in the given environment.
Karo Michaelian
doaj +1 more source
Alteration in the molecular structure of the adenine base exposed to gamma irradiation: An ESR study
Open Chemistry, 2023 Adenine polycrystals were obtained from their powder form under effective crystallization conditions by adjustment of the concentration of chemical solutions. The adenine samples were irradiated with a 60Co gamma-ray source at room temperature for 12, 24,
Usta Keziban
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Molbank, 2022 6-Amino-3-(prop-2-en-1-yl)-9H-purin-3-ium tetracopper(I) hexabromide [(C5H5N5(C3H5))2Cu4Br6] (1) is synthesized in this paper. The title compound is characterized by Raman spectroscopy and single crystal X-ray diffraction: monoclinic, Sp.gr. P21/c, Z = 2,
Oleksiy V. Pavlyuk +3 more
doaj +1 more source
Silver SERS Adenine Sensors with a Very Low Detection Limit
Biosensors, 2020 The detection of adenine molecules at very low concentrations is important for biological and medical research and applications. This paper reports a silver-based surface-enhanced Raman scattering (SERS) sensor with a very low detection limit for adenine
Yonhua Tzeng, Bo-Yi Lin
doaj +1 more source
Synthesis of purines and adenines containing the hexafluoroisopropyl group
Beilstein Journal of Organic Chemistry, 2020 Several new derivatives of adenine, purine, and theophylline containing the (CF3)2CH group connected to a nitrogen atom of the imidazole ring were prepared by the reaction of 2,2,4,4-tetrakis(trifluoromethyl)-1,3-dithietane (1) with the corresponding ...
Viacheslav Petrov +5 more
doaj +1 more source
Ribose supplementation alone or with elevated creatine does not preserve high energy nucleotides or cardiac function in the failing mouse heart [PDF]
, 2013 Background: Reduced levels of creatine and total adenine nucleotides (sum of ATP, ADP and AMP) are hallmarks of chronic heart failure and restoring these pools is predicted to be beneficial by maintaining the diseased heart in a more favourable energy ...
Aksentijevic, Dunja +6 more
core +7 more sources