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Construction and Anti-Cancer Activity of a Self-Assembly Composite Nano-Delivery System Loaded with Curcumin [PDF]

open access: yesMolecules
Natural products possess potent pharmacological activities and health benefits. However, drawbacks such as water insolubility, poor stability, and low bioavailability limit their practical applications.
Liang Chen   +6 more
doaj   +2 more sources

Preventive effects of the Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple on chronic kidney disease rats via modulating the intestinal microbiota and enhancing the intestinal barrier

open access: yesFrontiers in Pharmacology, 2022
CKD is a clinical syndrome with slow development and gradual deterioration of renal function. At present, modern medicine still lacks an ideal treatment method for this disease, while TCM has accumulated rich clinical experience in the treatment of CKD ...
Ling Wang   +10 more
doaj   +1 more source

Effect of fetuin-A on adenine-induced chronic kidney disease model in male rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Objective(s): This study aimed to investigate the possible effects of fetuin-A on an adenine-induced chronic kidney disease (CKD) model in male rats.
Wesam Ashour   +3 more
doaj   +1 more source

The Non-Equilibrium Thermodynamics of Natural Selection: From Molecules to the Biosphere

open access: yesEntropy, 2023
Evolutionary theory suggests that the origin, persistence, and evolution of biology is driven by the “natural selection” of characteristics improving the differential reproductive success of the organism in the given environment.
Karo Michaelian
doaj   +1 more source

Alteration in the molecular structure of the adenine base exposed to gamma irradiation: An ESR study

open access: yesOpen Chemistry, 2023
Adenine polycrystals were obtained from their powder form under effective crystallization conditions by adjustment of the concentration of chemical solutions. The adenine samples were irradiated with a 60Co gamma-ray source at room temperature for 12, 24,
Usta Keziban
doaj   +1 more source

6-Amino-3-(prop-2-en-1-yl)-9H-purin-3-ium Tetracopper(I) Hexabromide: Synthesis and X-ray Structure Determination

open access: yesMolbank, 2022
6-Amino-3-(prop-2-en-1-yl)-9H-purin-3-ium tetracopper(I) hexabromide [(C5H5N5(C3H5))2Cu4Br6] (1) is synthesized in this paper. The title compound is characterized by Raman spectroscopy and single crystal X-ray diffraction: monoclinic, Sp.gr. P21/c, Z = 2,
Oleksiy V. Pavlyuk   +3 more
doaj   +1 more source

Silver SERS Adenine Sensors with a Very Low Detection Limit

open access: yesBiosensors, 2020
The detection of adenine molecules at very low concentrations is important for biological and medical research and applications. This paper reports a silver-based surface-enhanced Raman scattering (SERS) sensor with a very low detection limit for adenine
Yonhua Tzeng, Bo-Yi Lin
doaj   +1 more source

Uraemic Cardiomyopathy in Different Mouse Models

open access: yesFrontiers in Medicine, 2021
Uraemic cardiomyopathy (UCM) is one of the most common complications in chronic kidney disease (CKD). Our aim was to compare characteristics of various UCM mouse models. Mice were assigned to the following groups: the pole ligation group, 5/6 nephrectomy
Cheng Chen   +7 more
doaj   +1 more source

Synthesis of purines and adenines containing the hexafluoroisopropyl group

open access: yesBeilstein Journal of Organic Chemistry, 2020
Several new derivatives of adenine, purine, and theophylline containing the (CF3)2CH group connected to a nitrogen atom of the imidazole ring were prepared by the reaction of 2,2,4,4-tetrakis(trifluoromethyl)-1,3-dithietane (1) with the corresponding ...
Viacheslav Petrov   +5 more
doaj   +1 more source

Adenine and Thymine Effect on Quartz Dissolution at Different Artificial Seawaters

open access: yesOrbital: The Electronic Journal of Chemistry, 2018
According to Bernal (1951) minerals may have played important roles in the origin of life such as: protect biomolecules against degradation by UV radiation or hydrolysis, pre-concentrate biomolecules from prebiotic seas and formation of polymers.
Dimas Augusto Morozin Zaia   +2 more
doaj   +3 more sources

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