Results 181 to 190 of about 393,841 (281)

ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models. [PDF]

Sci Rep
Ong JK, Bhunia S, Hilbert B, Kirschner V, Duglosz S, Zimmermann F, Freichel M, Cornean A.   +7 more
europepmc   +1 more source

Two‐Step Synthesis of a Chiral Fluorinated Alcohol With Silica‐Supported Enzyme RrADH in Batch and Continuous Flow Mode

Chemistry – A European Journal, EarlyView.
A two‐step process was transferred from batch to flow mode for the synthesis of (R)‐2‐fluoro‐1‐phenylethanol as a benchmark, consisting of a decarboxylative fluorination in aqueous media, followed by an enantioselective biocatalytic reduction of the prochiral intermediate with RrADH immobilized on silica supraparticles.
Egzon Cermjani, Greta Nölke, Stefano Di Fiore, Christoph Deckers, Doris Hanselmann, Bettina Herbig, Susanne Wintzheimer, Thomas H. Rehm   +7 more
wiley   +1 more source

Atomistic QM/Classical Modeling of Surface-Enhanced Infrared Absorption. [PDF]

J Phys Chem C Nanomater Interfaces
Sodomaco S, Lafiosca P, Giovannini T, Cappelli C.   +3 more
europepmc   +1 more source

Construction of a CO2‐Fixing Compartment Using a Shape‐Transforming DNA Scaffold

Chemistry – A European Journal, EarlyView.
A shape‐transforming DNA scaffold encapsulates RuBisCO within a controllable, self‐contacting compartment that mimics the carboxysome. The scaffold switches between open and closed states, enabling direct comparison of identical enzyme populations in different microenvironments.
Hui Yang, Peng Lin, Surachada Chuaychob, Huyen Dinh, Mei Nakabayashi, Eiji Nakata, Takashi Morii   +6 more
wiley   +1 more source

ILK Deletion Protects Against Chronic Kidney Disease-Associated Vascular Damage. [PDF]

Int J Mol Sci
Campillo S, Gutiérrez-Calabrés E, García-Miranda S, Griera M, de Frutos S, Rodríguez-Puyol D, Calleros L.   +6 more
europepmc   +1 more source

Rational Design Strategies for Stimuli‐Responsive DNAzymes Using Modified and Artificial Nucleotides

Chemistry – A European Journal, EarlyView.
Activity control of RNA‐cleaving DNAzymes in response to external stimuli has attracted growing interest for applications in DNA‐based diagnostics, therapeutics, and dynamic DNA nanotechnology. This review summarizes rational design strategies for stimuli‐responsive DNAzymes using modified or artificial nucleotides, including split and caged DNAzymes ...
Yusuke Takezawa, Mitsuhiko Shionoya
wiley   +1 more source

Mechanistic studies on HNRNPA2B1 suggest binding but not selective recognition of m⁶A. [PDF]

RNA Biol
Park R, Demny M, Miller LG, Pedraza C, Xenophontos X, Hunt RK, Orr AA, Perez LM, Montalbano M, Contreras LM, Tamamis P.   +10 more
europepmc   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

A Novel Murine Model Integrating Peripheral Arterial Disease and Multiorgan Dysfunction: Unraveling Cardiovascular-Kidney-Metabolic Complexity. [PDF]

Kidney360
Kane J, Misra S, Misra S.
europepmc   +1 more source

Asymmetric Reduction of Unactivated Alkenes

Chemistry – A European Journal, EarlyView.
Unactivated alkenes rank among the most inert functional groups in synthesis and their selective reduction remains challenging. This Review charts the evolution from classical metal‐catalyzed hydrogenation to radical hydrogen atom transfer (HAT) and emerging biocatalytic concepts, highlighting how complementary mechanistic strategies, including the ...
Nico D. Fessner, Sebastian Roth, Richard Niese, Michael Müller   +3 more
wiley   +1 more source