Results 181 to 190 of about 401,272 (328)

POTENTIATION OF ADENOSINE AND THE ADENINE NUCLEOTIDES BY DIPYRIDAMOLE [PDF]

, 1966
Anne Stafford
openalex   +1 more source

Mortalin and PINK1/Parkin‐Mediated Mitophagy Represent Ovarian Cancer‐Selective Targets for Drug Development

Advanced Science, EarlyView.
Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra, Justin Garland, Rajani Rai, Donghua Zhao, Charuksha Walgama, Sadagopan Krishnan, Andrew T. Long, Tongzu Liu, Laura Adhikari, Doris M. Benbrook   +9 more
wiley   +1 more source

Phosphate salt selection affects mortality and vascular calcification in the adenine-induced chronic kidney disease mouse model. [PDF]

Am J Physiol Heart Circ Physiol
Dargam V, Ashbrook SK, da Silva Nogueira P, Bakhshian Nik A, Hutcheson JD.   +4 more
europepmc   +1 more source

THE ADENINE NUCLEOTIDE CONTENT OF HUMAN BLOOD

, 1936
Mary V. Buell
openalex   +1 more source

Electrochemical Oxidation of Adenine: Reaction Products and Mechanisms [PDF]

, 1968
Glenn Dryhurst, Philip J. Elving
openalex   +1 more source

Src Reduces Neutrophil Extracellular Traps Generation and Resolves Acute Organ Damage

Advanced Science, EarlyView.
Src reduces neutrophil extracellular traps (NETs) generation and resolves acute organ damage. Src directly activates RAF1 by regulating phosphorylation at the Ser 621 site and mediates the RAF/MEK/ERK pathway, thereby affecting the intracellular ROS production. Alternatively, Src activates the RAF1/MEK/ERK pathway by mediating PKC phosphorylation.
Guotao Lu, Fei Han, Yaodong Wang, Chenchen Yuan, Qingtian Zhu, Tianqi Xia, Lin Chen, Xiaowu Dong, Yanbing Ding, Weiming Xiao, Yuyan Zhang, Jiajia Pan, Hongwei Xu, Weiwei Chen, Bo Tu, Wei Li, Fei Wang, Weijuan Gong, Lianghao Hu   +18 more
wiley   +1 more source

diPaRIS: Dynamic and Interpretable Protein‐RNA Interactions Prediction With U‐Shaped Network and Novel Structure Encoding

Advanced Science, EarlyView.
This study presents diPaRIS, a deep learning method designed to predict dynamic protein‐ RNA interactions with enhanced accuracy. By integrating RNA structures in vivo through a novel encoding scheme for nucleotide correlations, diPaRIS improves the interpretability of binding motifs and outperforms current state‐of‐the‐art methods across multiple ...
Lishen Zhang, Chengqian Lu, Xiaoqing Peng, Fei Guo, Hongdong Li, Jianxin Wang   +5 more
wiley   +1 more source

A SIMPLIFIED PREPARATION METHOD OF P32- LABELED FLAVIN MONONUCLEOTIDE AND FLAVIN-ADENINE DINUCLEOTIDE AND THEIR APPLICATION TO BIOCHEMICAL RESEARCHES

, 1959
K Hotta, Isao Ishiguro, Mamoru Sugiura, Nobuhiko Katunuma, Kazutoshi Kojima, TOSHIYUKI HISHIKI, Yoshio Ikegami   +6 more
openalex   +2 more sources

A Viral RNA Silencing Suppressor Modulates Reactive Oxygen Species Levels to Induce the Autophagic Degradation of Dicer‐Like and Argonaute‐Like Proteins

Advanced Science, EarlyView.
Understanding the virus‐host arms race has been a fascinating topic in virology; contributing significantly to the development of treatments and control strategies for viral diseases. CHV1 employs a sophisticated counter‐defense mechanism in its fungal host by utilizing a viral silencing suppressor to inhibit fungal FMN reductase; thereby modulating ...
Shiyu Zhai, Tianxing Pang, Shiyu Peng, Shenshen Zou, Zhiping Deng, Nobuhiro Suzuki, Zhensheng Kang, Ida Bagus Andika, Liying Sun   +8 more
wiley   +1 more source

Biosynthesis of microsomal nicotinamide–adenine dinucleotide phosphate–cytochrome c reductase by membrane-bound and free polysomes from rat liver [PDF]

, 1969
G. Ragnotti, G. Ross Lawford, P.N. Campbell   +2 more
openalex   +1 more source