Results 181 to 190 of about 399,190 (328)

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

Introducing the "other" type of DNA methylation. [PDF]

Sci Adv
Bochtler M.
europepmc   +1 more source

GLYCINE AND ADENINE AS PRECURSORS OF NUCLEIC ACID PURINES IN TUMOR-BEARING MICE

, 1955
Ralph K. Barclay, Esther Garfinkel
openalex   +1 more source

Single-stranded, adenine-rich RNA from purified reoviruses. [PDF]

, 1968
Aaron J. Shatkin, Jean D. Sipe
openalex   +1 more source

Untying Surface Chemistry and Emulsion Stability to Construct Multifunctional Pickering Emulsion SERS Sensors for Pretreatment‐Free Quantitative Analysis in Bio‐Media

Advanced Science, EarlyView.
A dual‐particle interfacial self‐assembly approach is used to create surface‐accessible Pickering emulsions with Au@Prussian blue nanoparticles acting as the functional component. These emulsions have strong plasmonic properties and are equipped with molecular sieves and internal standards.
Yingrui Zhang, Chunchun Li, Ruairi Carland, Ziwei Ye, Steven E. J. Bell, Yikai Xu   +5 more
wiley   +1 more source

An adenine model of inborn metabolism errors alters TDP-43 aggregation and reduces its toxicity in yeast revealing insights into protein misfolding diseases. [PDF]

Microb Cell
Park S, Park SK, Blair P, Liebman SW.
europepmc   +1 more source

WTAP Mediated m6A Modification Stabilizes PDIA3P1 and Promotes Tumor Progression Driven by Histone Lactylation in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a new mechanism by which PDIA3P1 regulates the progression of esophageal squamous cell carcinoma (ESCC). PDIA3P1 upregulates the expression of GLUT1 and HK2, promoting glycolysis and lactate production. Lactate upregulates the lactylation level of histone H4K8 and activates the transcription of target gene BMP7, ultimately ...
Tao Huang, Qi You, Jiawei Liu, Xuguang Shen, Dengjun Huang, Xinlu Tao, Zhijie He, Chengwei Wu, Xinran Xi, Shouqiang Yu, Feng Liu, Zhihao Wu, Wenjun Mao, Shaojin Zhu   +13 more
wiley   +1 more source

Probing the Coupled Equilibria between Metal Nanoparticles, Antibiotics and Components of the Extracellular Matrix in Biofilms with SERS. [PDF]

Biomacromolecules
Aljuhani W, Wylie MP, Purusottam RN, McCoy CP, Bell SEJ.   +4 more
europepmc   +1 more source

THE ADENINE NUCLEOTIDE CONTENT OF HUMAN BLOOD

, 1936
Mary V. Buell
openalex   +1 more source

ROS‐Responsive Hydrogel for Localized Delivery of Nampt and Stat3 Inhibitors Exhibits Synergistic Antitumor Effects in Colorectal Cancer Through Ferroptosis Induction and Immune Microenvironment Remodeling

Advanced Science, EarlyView.
In this study, ferroptosis in colorectal cancer cells is induced by FK866 through the NAD⁺/STAT3/GPX4 pathway. To minimize systemic toxicity, a reactive oxygen species (ROS)‐responsive hydrogel is developed to co‐deliver FK866 and C188‐9, resulting in synergistic and localized antitumor effects.
Chenyang Ye, Mi Mi, Saimeng Shi, Lina Qi, Shanshan Weng, Lu Wang, Yier Lu, Chao Chen, Yinuo Tan, Mengyuan Yang, Cheng Guo, Rui Bai, Xuefeng Fang, Ji Wang, Ying Yuan   +14 more
wiley   +1 more source