Results 171 to 180 of about 276,635 (308)

Pharmacological antagonism of HTR2B reduces ERK and STAT3 activation and prevents renal fibrosis during the development of Adenine-Induced CKD in rats. [PDF]

Biochem Pharmacol
McAlister KW, Scholpa NE, Janda J, Schnellmann RG.   +3 more
europepmc   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

Biological Reviews, EarlyView.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source

IFN-γ-dominant immune shift is associated with reduced protective ILC2 responses in chronic kidney disease. [PDF]

Front Immunol
Kuno Y, Ishikawa H, Nagashima R, Matsuzaka Y, Kohda C, Kanazawa N, Suzuki T, Isozaki T, Kuwata H, Iyoda M.   +9 more
europepmc   +1 more source

Adenine [PDF]

, 2019
openaire   +1 more source

The influence of circadian variables on ecotoxicology metabolomics

Biological Reviews, EarlyView.
ABSTRACT Ecotoxicologists are using metabolomics increasingly to gain insight into toxicological mechanisms and sublethal effects of chemical exposures. Metabolomics offers a sensitive multi‐parameter approach that can detect biochemical responses not obvious using apical and behavioural endpoints.
Ryan I. Lester, David J. Beale, Anthony R. Carroll, Steven D. Melvin   +3 more
wiley   +1 more source

Disulfiram Attenuates Adenine-Induced Renal Fibrosis by Modulating Inflammatory and Immunometabolic Responses. [PDF]

FASEB J
Kin S, Oe Y, Ishigaki S, Fujio I, Miyazaki M, Tanaka T.   +5 more
europepmc   +1 more source

Prefrontal Planning Latency Associated With Age and Serological Evidence of Microbial Exposure

Chronic Diseases and Translational Medicine, EarlyView.
Planning latency versus age by group. Scatterplot showing individual observations (n = 53) stratified by fibromyalgia status. LOESS smoothing curves with 95% confidence intervals (shaded regions) illustrate the relationship within each group. Overall, rₛ = 0.394 (p = 0.003).
Basant K. Puri, Rosemarie Preyer, Gary S. Lee, Lucy Monaghan, Armin Schwarzbach   +4 more
wiley   +1 more source

Formation of Lanthanide Luminescent Aggregates With RNA Using Tripodal Europium [Eu(III)] BTA Self‐Assembled Complexes

Chemistry – A European Journal, EarlyView.
The two Eu(III) complexes of 1.Eu and 2.Eu, that were formed in situ, were used to bind to yeast RNA and A10 (RNA) in a buffered pH 7 solution. The interaction gave rise to changes in the lanthanide‐centered emission because of direct binding of these complexes, which resulted in aggregation of the RNA, as demonstrated using phase‐contrast and atomic ...
Tómas A. Gudmundsson, Changzhuang Bai, Grace E. Maynard, Pall Thordarson, Thorfinnur Gunnlaugsson   +4 more
wiley   +1 more source

DNA Damage Recognition by Bacterial and Human Adenine-DNA Glycosylases: Insights from Non-Canonical Substrates. [PDF]

Biomolecules
Sarsenbayeva U, Gasparutto D, Geacintov N, Ishchenko AA, Zhamanbayeva G, Sharipov KO, Trasviña-Arenas CH, David SS, Zharkov DO, Matkarimov BT, Saparbaev M, Taipakova S.   +11 more
europepmc   +1 more source