Results 11 to 20 of about 417,743 (333)

Electron transfer driven decomposition of adenine and selected analogs as probed by experimental and theoretical methods [PDF]

open access: bronze, 2018
We report on a combined experimental and theoretical study of electron transfer induced decomposition of adenine and a selection of analogue molecules in collisions with potassium atoms (K).
Bacchus-Montabonel, M.-C.   +6 more
core   +6 more sources

Therapeutic potential of L-Carnitine in improving adenine-induced hematological abnormalities in rats: A preclinical pharmacological study [PDF]

open access: yesOpen Veterinary Journal
Background: Adenine is a naturally occurring purine essential for life, but its excess intake can cause metabolic disturbances leading to cardiovascular complications, renal stones, gout, fatigue, and anemia.
Waleed Khaled Y. Albahadly   +4 more
doaj   +2 more sources

Preventive effects of the Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple on chronic kidney disease rats via modulating the intestinal microbiota and enhancing the intestinal barrier

open access: yesFrontiers in Pharmacology, 2022
CKD is a clinical syndrome with slow development and gradual deterioration of renal function. At present, modern medicine still lacks an ideal treatment method for this disease, while TCM has accumulated rich clinical experience in the treatment of CKD ...
Ling Wang   +10 more
doaj   +1 more source

Effect of fetuin-A on adenine-induced chronic kidney disease model in male rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Objective(s): This study aimed to investigate the possible effects of fetuin-A on an adenine-induced chronic kidney disease (CKD) model in male rats.
Wesam Ashour   +3 more
doaj   +1 more source

Alteration in the molecular structure of the adenine base exposed to gamma irradiation: An ESR study

open access: yesOpen Chemistry, 2023
Adenine polycrystals were obtained from their powder form under effective crystallization conditions by adjustment of the concentration of chemical solutions. The adenine samples were irradiated with a 60Co gamma-ray source at room temperature for 12, 24,
Usta Keziban
doaj   +1 more source

6-Amino-3-(prop-2-en-1-yl)-9H-purin-3-ium Tetracopper(I) Hexabromide: Synthesis and X-ray Structure Determination

open access: yesMolbank, 2022
6-Amino-3-(prop-2-en-1-yl)-9H-purin-3-ium tetracopper(I) hexabromide [(C5H5N5(C3H5))2Cu4Br6] (1) is synthesized in this paper. The title compound is characterized by Raman spectroscopy and single crystal X-ray diffraction: monoclinic, Sp.gr. P21/c, Z = 2,
Oleksiy V. Pavlyuk   +3 more
doaj   +1 more source

Purine Synthesis Inhibitor L-Alanosine Impairs Mitochondrial Function and Stemness of Brain Tumor Initiating Cells

open access: yesBiomedicines, 2022
Glioblastoma (GBM) is a lethal brain cancer exhibiting high levels of drug resistance, a feature partially imparted by tumor cell stemness. Recent work shows that homozygous MTAP deletion, a genetic alteration occurring in about half of all GBMs ...
Simranjit X. Singh   +8 more
doaj   +1 more source

Silver SERS Adenine Sensors with a Very Low Detection Limit

open access: yesBiosensors, 2020
The detection of adenine molecules at very low concentrations is important for biological and medical research and applications. This paper reports a silver-based surface-enhanced Raman scattering (SERS) sensor with a very low detection limit for adenine
Yonhua Tzeng, Bo-Yi Lin
doaj   +1 more source

The Non-Equilibrium Thermodynamics of Natural Selection: From Molecules to the Biosphere

open access: yesEntropy, 2023
Evolutionary theory suggests that the origin, persistence, and evolution of biology is driven by the “natural selection” of characteristics improving the differential reproductive success of the organism in the given environment.
Karo Michaelian
doaj   +1 more source

CoCl2-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors

open access: yesBiomedicines, 2022
Chronic hypoxia drives vascular dysfunction by various mechanisms, including changes in mitochondrial respiration. Although endothelial cells (ECs) rely predominantly on glycolysis, hypoxia is known to alter oxidative phosphorylation, promote oxidative ...
Barbara Kutryb-Zajac   +6 more
doaj   +1 more source

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