Results 201 to 210 of about 399,190 (328)

Autofluorescence Imaging and Virtual Histological Staining of Human Prostate Sections for Cancer Diagnosis

open access: yesAdvanced Intelligent Systems, EarlyView.
Autofluorescence imaging with virtual histological staining streamlines postoperative histopathology. Using a deep ultraviolet light‐emitting diode (LED)‐based imaging system and a weakly supervised deep learning model, virtual hematoxylin and eosin (H&E)‐stained images are generated from the autofluorescence of prostate tissue. Pathologist evaluations
Mingxuan Si   +9 more
wiley   +1 more source

Remote Control of Eukaryotic Gene Expression by a Modular Ultrasound‐Responsive RNA Toolkit

open access: yesAngewandte Chemie, EarlyView.
A modular RNA‐based sonogenetic toolkit enables remote control of gene expression in eukaryotes by releasing small molecule modulators from ultrasound‐responsive carriers. These modulators activate engineered mRNA elements such as riboswitches, leading to tunable protein expression.
Fahimeh Charbgoo   +7 more
wiley   +2 more sources

Dual Role of Exosomes in Parkinson's Disease: Adenine Exerts a Beneficial Effect. [PDF]

open access: yesCNS Neurosci Ther
Chen L   +6 more
europepmc   +1 more source

Studies on the Biosynthesis of Nicotinamide Adenine Dinucleotide

open access: hybrid, 1965
Masayuki Ikeda   +5 more
openalex   +1 more source

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin‐Independent Regulation of Fpn mRNA

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) by inhibiting the iron exporter ferroportin in target cells, causing hypoferremia. Under acute inflammation, hepcidin induction requires hemojuvelin (Hjv), a bone morphogenetic protein co‐receptor, while Fpn mRNA is also suppressed in a hepcidin‐
Siqi Liu   +3 more
wiley   +1 more source

Phenotypical and Genotypical Expansion of Autosomal‐Dominant KDM1A‐Related Neurodevelopmental Disorder Spectrum: A Case Report

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT KDM1A‐related neurodevelopmental disorder (CPRF, OMIM #616728) is characterized by cleft palate, global developmental delay, and distinct facial gestalt, but phenotypic knowledge of this ultra‐rare autosomal dominant disorder is limited. Here, we report on a 13‐year‐old boy with a novel heterozygous, likely pathogenic germline missense variant
Sebastian Burkart   +6 more
wiley   +1 more source

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