Results 221 to 230 of about 417,743 (333)

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

PET imaging of mitochondrial complex-I in the adenine-induced tubulointerstitial nephropathy mouse model using [¹⁸F]BCPP-BF. [PDF]

EJNMMI Radiopharm Chem
Dahl K, Johnström P, Toth M, Sousa VC, Ericsson C, Strömstedt M, Inghardt T, Cortés González MA, Reznichenko A, Jucaite A, Cselényi Z, Unwin R, Ohba H, Halldin C, Challis B, Tsukada H, Schou M.   +16 more
europepmc   +1 more source

ZSF1 lean rats – How healthy are they?

Animal Models and Experimental Medicine, EarlyView.
This study aimed to examine the health status, specifically the physiology and myocardial, vascular, and skeletal muscle function of lean ZSF1 rats by comparing them to age‐ and sex‐matched Wistar rats. Compared to Wistar controls, ZSF1 lean rats exhibited lower body weight, but showed increased heart, and skeletal muscle mass.
Antje Schauer, Beatrice Vahle, Volker Adams, Axel Linke, Antje Augstein   +4 more
wiley   +1 more source

When the Stones Keep Hitting, Leave No Stone Unturned: A Report of Two Cases of Adenine Phosphoribosyltransferase (APRT) Deficiency Progressing to End-Stage Renal Failure and Recurrence Post-transplant in One of Them. [PDF]

Cureus
Chafekar N, Omosule B, Aldujaili M, Kamalanathan M.   +3 more
europepmc   +1 more source

Flavin Adenine Dinucleotide Status and the Effects of High-Dose Riboflavin Treatment in Short-Chain Acyl-CoA Dehydrogenase Deficiency [PDF]

, 2010
Bianca T. van Maldegem, Marinus Durán, Ronald J. A. Wanders, Hans R. Waterham, Frits A. Wijburg   +4 more
openalex   +1 more source

Establishment of a novel cynomolgus monkey model of hyperuricemia

Animal Models and Experimental Medicine, EarlyView.
We established a novel hyperuricemia model in cynomolgus monkeys (A) via oral administration of potassium oxonate, hydrochlorothiazide, and adenine mixed in fruits and vegetables. This model (B) targets uric acid synthesis and enzymatic degradation, and (C) regulates renal and intestinal excretion, thereby stably elevating serum uric acid and serving ...
Ji‐Wei Wang, Le Zhang, Can Yang, Guan‐Cong Luo, Rui‐Chang Liu, Yan‐Jun Xu, Sheng Cheng, Wen‐Yu Jiang, Richard Ward, Yang Yang, Cheng Xiang, Shu An, Tian‐Rui Xu   +12 more
wiley   +1 more source

Photochemical N‐dealkylation of Tertiary Amines Coupled With Photocharging of Poly(Heptazine Imides)

Angewandte Chemie, EarlyView.
Protonated poly(heptazine imide) (H‐PHI) functions as an energy reservoir, thereby facilitating the endothermic dealkylation of triethylamine through a proton‐coupled two‐electron transfer (PC2ET) process. The extent of photocharging is quantitatively described by a molecular‐level descriptor, Ne:Nhept, providing a direct correlation between stored ...
Jingru Zhuang, Quanhao Zhang, Chong Wang, Tao Yao, Cheuk Lok Cheng, Pavlo O. Dral, Oleksandr Savateev   +6 more
wiley   +2 more sources

Ultraviolet Photodissociation Spectroscopy of [dAMP-H]^- at Low Temperature. [PDF]

J Phys Chem A
Sprenger C, White SJM, Westermeier M, Schöpfer G, Dahlmann F, Namangalam U, Mohandas S, Kumar S S, Endres ES, Ončák M, Wester R.   +10 more
europepmc   +1 more source

Antimicrobial Activity of Adenine-Based Inhibitors of NAD⁺-Dependent DNA Ligase

, 2012
Ed T. Buurman, Valerie A. Laganas, Ce Feng Liu, John I. Manchester   +3 more
openalex   +1 more source

A Novel Transcriptional Slippage Mechanism Rescues Dystrophin Expression from a DMD Frameshift Variant

Annals of Neurology, EarlyView.
Pathogenic DMD variants usually follow the reading‐frame rule: out‐of‐frame changes cause Duchenne muscular dystrophy, whereas in‐frame ones produce Becker muscular dystrophy (BMD). We report a 23‐year‐old man with BMD‐like weakness, calf hypertrophy, elevated creatine kinase, and dilated cardiomyopathy.
Hiroya Naruse, Jun Mitsui, Akatsuki Kubota, So Okubo, Shuichiro Mitsuchi, Kensho Sumi, Shuichi Tanifuji, Shogo Komaki, Asuka Kitamura, Meiko Maeda, Daiki Yashita, Atsushi Sudo, Takashi Matsukawa, Masashi Hamada, Wataru Satake, Shoji Tsuji, Tatsushi Toda   +16 more
wiley   +1 more source