Results 241 to 250 of about 417,743 (333)

Adenin-Phosphoribosyltransferase [PDF]

, 2017
openaire   +1 more source

Dihydroxyacetone decreases the dATP pool, inducing replication stress and genomic instability in BEAS-2B cells. [PDF]

J Biol Chem
Hussain S, Mukherjee N, Gassman NR.
europepmc   +1 more source

The function of complexes between the outer mitochondrial membrane pore (VDAC) and the adenine nucleotide translocase in regulation of energy metabolism and apoptosis.

, 2003
M. Yu. Vyssokikh, Dieter Brdiczka
openalex   +2 more sources

Phase Separation of Nucleic Acids: Mechanisms, Properties, and Applications

Angewandte Chemie International Edition, EarlyView.
Recent discoveries have shown that single‐stranded long‐chain nucleic acids can undergo temperature‐induced phase separation, enabling formation of micrometer‐sized condensates. This Minireview discusses the current mechanistic understanding of this phenomenon, highlights strategies for controlling the physical and chemical properties of these ...
Weixiang Chen, Johann Fritzen, Andreas Walther   +2 more
wiley   +1 more source

“Reversine” and Its 2-Substituted Adenine Derivatives as Potent and Selective A₃ Adenosine Receptor Antagonists

, 2005
Melissa Perreira, Jian‐kang Jiang, Athena M. Klutz, Zhan‐Guo Gao, Asher Shainberg, Changrui Lu, Craig J. Thomas, Kenneth A. Jacobson   +7 more
openalex   +2 more sources

Spermidine Reproduces the Anti‐Inflammatory Effects of Intermittent Fasting and Prevents Urate and Calcium Pyrophosphate Crystal‐Induced Inflammation

Arthritis &Rheumatology, EarlyView.
Objective Gout caused by the formation of monosodium urate (MSU) crystals and calcium pyrophosphate (CPP) deposition disease are two major types of microcrystalline pathologies in adults. They are responsible for recurrent flares that rely on interleukin (IL) 1β via activation of the NLRP3 inflammasome.
Chinh Nghia Pham, Florence Castelli, Flora Finet, Charles Leroy, Céline Chollet, Twinu W. Chirayath, Subhalaxmi Moitra, Mylène Zarka, Agnès Ostertag, François Brial, Christèle Combes, Augustin Latourte, Thomas Bardin, François Fenaille, Pascal Richette, Hang Korng Ea   +15 more
wiley   +1 more source

2,8-Dihydroxyadenine disrupts epithelial integrity and alters kidney cell phenotype in vitro. [PDF]

J Mol Med (Berl)
Helgudottir HR, Palsson R, Edvardsson VO, Gudjonsson T.   +3 more
europepmc   +1 more source

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

Arthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H.W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Solid-Phase Synthesis Approaches and U-Rich RNA-Binding Activity of Homotrimer Nucleopeptide Containing Adenine Linked to <i>L</i>-azidohomoalanine Side Chain via 1,4-Linked-1,2,3-Triazole. [PDF]

Int J Mol Sci
Mucha P, Pieszko M, Bylińska I, Wiczk W, Ruczyński J, Rekowski P.   +5 more
europepmc   +1 more source

REVERSIBLE ENZYMATIC SYNTHESIS OF FLAVIN-ADENINE DINUCLEOTIDE

, 1950
Anthony W. Schrecker, Arthur Kornberg
openalex   +1 more source