Results 41 to 50 of about 487,247 (373)

Can adenine nucleotides predict primary nonfunction of the human liver homograft? [PDF]

open access: yes, 1994
Sixty-eight primary liver grafts were analyzed to see whether adenine nucleotides (AN: ATP, ADP, and AMP) or purine catabolites (PC: adenosine, inosine, hypoxanthine, and xanthine) of tissue or effluent can predict primary graft nonfunction.
Bronsther, O   +8 more
core   +1 more source

Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses

open access: yesNature Biomedical Engineering, 2019
The success of base editors for the study and treatment of genetic diseases depends on the ability to deliver them in vivo to the relevant cell types. Delivery via adeno-associated viruses (AAVs) is limited by AAV packaging capacity, which precludes the ...
Jonathan M. Levy   +9 more
semanticscholar   +1 more source

The Effect of Metformin in Diabetic and Non-Diabetic Rats with Experimentally-Induced Chronic Kidney Disease

open access: yesBiomolecules, 2021
This work aimed to investigate whether treatment with the antidiabetic drug metformin would affect adenine-induced chronic kidney disease (CKD) in non-diabetic rats and rats with streptozotocin (STZ)-induced diabetes.
Mohammed Al Za’abi   +7 more
doaj   +1 more source

Sensitive Silver-Enhanced Microplate Apta-Enzyme Assay of Sb3+ Ions in Drinking and Natural Waters

open access: yesMolecules, 2023
The toxic effects of antimony pose risks to human health. Therefore, simple analytical techniques for its widescale monitoring in water sources are in demand. In this study, a sensitive microplate apta-enzyme assay for Sb3+ detection was developed.
Nadezhda S. Komova   +4 more
doaj   +1 more source

Back-electron transfer suppresses the periodic length dependence of DNA-mediated charge transport across adenine tracts [PDF]

open access: yes, 2008
DNA-mediated charge transport (CT) is exquisitely sensitive to the integrity of the bridging π-stack and is characterized by a shallow distance dependence. These properties are obscured by poor coupling between the donor/acceptor pair and the DNA bridge,
Augustyn, Katherine E.   +4 more
core   +2 more sources

Two small-volume electrochemical cells for the measurement of surface enhanced Raman scattering [PDF]

open access: yes, 1984
Two electrochemical cells, for performing surface enhanced Raman scattering (SERS), with submillilitre volumes are presented. One of the cells is especially developed for use in a Raman microspectrometer.
Greve, J.   +5 more
core   +2 more sources

A new mechanistic insight of DNA base adenine formation from pentamer HCN in the gas phase of interstellar clouds

open access: yesJournal of Taibah University for Science, 2019
The mechanism formation of adenine is determinate in the gas phase, by using density functional theory (DFT) method at the B3LYP hybrid together with 6-311g(d,p) basis set level. Thus, we have investigated the structures and mechanisms pathway as well as
Abdelilah Benallou
doaj   +1 more source

Adenine decreases hypertrophic effects through interleukin-18 receptor

open access: yesChinese Journal of Physiology, 2019
Cardiac hypertrophy is the main cause of heart failure. Levels of circulating interleukin-18 (IL-18) have been reported to increase in congestive heart disease and cardiac hypertrophy. Relationships among IL-18 levels, IL-18 receptor (IL-18R) expression,
Yi-Feng Yang, Yao-Jen Liang
doaj   +1 more source

(1RS,2RS,6RS)-2-(6-Amino-9H-purin-9-yl)-8-azaspiro[5.6]dodec-10-en-1-ol Dihydrochloride

open access: yesMolbank, 2022
The title compound (1RS,2RS,6RS)-2-(6-Amino-9H-purin-9-yl)-8-azaspiro[5.6]dodec-10-en-1-ol dihydrochloride was synthesized for the first time in two steps, the first of which was a regioselectivity of epoxide ring-opening reaction under the action of ...
Ildar R. Iusupov   +3 more
doaj   +1 more source

The Dissipative Photochemical Origin of Life: UVC Abiogenesis of Adenine

open access: yesEntropy, 2021
The non-equilibrium thermodynamics and the photochemical reaction mechanisms are described which may have been involved in the dissipative structuring, proliferation and complexation of the fundamental molecules of life from simpler and more common ...
Karo Michaelian
doaj   +1 more source

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