Results 51 to 60 of about 47,793 (252)

Mutual Relations between Substituent Effect, Hydrogen Bonding, and Aromaticity in Adenine-Uracil and Adenine-Adenine Base Pairs

open access: yesMolecules, 2020
The electronic structure of substituted molecules is governed, to a significant extent, by the substituent effect (SE). In this paper, SEs in selected nucleic acid base pairs (Watson-Crick, Hoogsteen, adenine-adenine) are analyzed, with special emphasis ...
Paweł A. Wieczorkiewicz   +2 more
doaj   +1 more source

Mechanism study on the effect of adenine on the viability of Lactiplantibacillus plantarum LIP-1 powder via freeze-drying

open access: yesFood Science of Animal Products, 2023
Adenine acts as a growth promoter to promote the growth of the lactic acid bacteria (LAB), but the effect on the viability of freeze-dried strains has rarely been studied.
Qiaoling Zhang   +7 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Novel antibiotics from DNA adenine methyltransferase inhibitors

open access: yes, 2011
The re-emergence of plague as a world-wide health concern and the potential risk posed by bioterrorism has led to an increased interest in available treatments for the disease.
McKelvie, Jennifer C.
core   +1 more source

Poly-adenine-Coupled LAMP Barcoding to Detect Apple Scar Skin Viroid

open access: yes, 2018
Apple Scar Skin Viroid (ASSVd), a nonprotein coding, circular RNA pathogen is relatively difficult to detect by immunoassay. We report here a one-step reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay to improve selectivity for
Yang-Hoon Kim   +15 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

The effect of adenine adsorption on Zn (II) electroreduction in acetate buffer.

open access: yesActa Chimica Slovenica, 2018
The paper presents the thermodynamic analysis of adenine adsorption on a mercury electrode in an acetate buffer at pH 3 and pH 4. Adsorption energy and constants were determined using the Frumkin isotherm and the virial isotherm.
Dorota Gugała-Fekner
doaj   +1 more source

Polarographic Behaviour of Adenine [PDF]

open access: yesNature, 1946
WORK in this laboratory on differences in mechanism between normal and malignant cells has shown the great need for improved methods of analysis and characterization of nucleic acids. Investigations which I began before the War indicated to me the value of the polarograph as an analytical tool in the study of inorganic cell constituents, and there was ...
openaire   +2 more sources

Adenine-induced chronic kidney and cardiovascular damage in rats

open access: yes, 2013
Background: The incidence of human chronic kidney failure with associated cardiovascular disease is increasing. Kidney damage can be induced in rats by chronic dietary adenine intake.
Mistry, Anand   +3 more
core   +1 more source

Molecular dynamics simulation study of the binding of purine bases to the aptamer domain of the guanine sensing riboswitch [PDF]

open access: yes, 2009
Riboswitches are a novel class of genetic control elements that function through the direct interaction of small metabolite molecules with structured RNA elements.
Stock, Gerhard   +4 more
core   +1 more source

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