Results 71 to 80 of about 47,793 (252)

Adenine Phosphoribosyltransferase Deficiency [PDF]

Clinical Journal of the American Society of Nephrology, 2012
Summary Complete adenine phosphoribosyltransferase (APRT) deficiency is a rare inherited metabolic disorder that leads to the formation and hyperexcretion of 2,8-dihydroxyadenine (DHA) into urine. The low solubility of DHA results in precipitation of this compound and the formation of urinary crystals and stones.
Guillaume, Bollée, Jérôme, Harambat, Albert, Bensman, Bertrand, Knebelmann, Michel, Daudon, Irène, Ceballos-Picot   +5 more
openaire   +2 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

The impact of altered dietary adenine concentrations on the gut microbiota in Drosophila

Frontiers in Microbiology
The gut microbiota influences host metabolism and health, impacting diseases. Research into how diet affects gut microbiome dynamics in model organisms is crucial but underexplored. Herein, we examined how dietary adenine affects uric acid levels and the
Xianglin Yin, Xianglin Yin, Qing Tong, Jingtao Wang, Jinfeng Wei, Zhenbo Qin, Yujie Wu, Ruidi Zhang, Baosheng Guan, Hongbin Qiu, Hongbin Qiu   +10 more
doaj   +1 more source

Sequencing and analysis of the DNA genome of the temperate bacteriophage Aa[Phi]23 of "Actinobacillus actinomycetemcomitans" [PDF]

, 2005
The entire genomic sequence of the AaΦ23 bacteriophage is presented. Its size is 43,033 bp and it has an overall molar G+C content of 41mol%. 57 potential open reading frames (ORFs) were identified.
Resch, Grégory
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

HOTSPOT STABILIZATION OF GOLD NANOPARTICLES FOR APPLICATION OF QUANTITATIVE SERS IN BIOANALYTICAL SYSTEMS [PDF]

Química Nova
A complete procedure including synthesizing gold nanoparticles and further hotspots stabilization is presented. Colloidal gold synthesis followed a citrate reducing reaction, then, an ideal condition for SERS enhancement with quantitative purposes was ...
Mónica B. Mamián-López, Marcia L. A. Temperini   +1 more
doaj   +2 more sources

Novel Cd (II) Coordination Polymers Afforded with EDTA or Trans-1,2-Cdta Chelators and Imidazole, Adenine, or 9-(2-Hydroxyethyl) Adenine Coligands

Crystals, 2020
Three mixed-ligands of Cd(II) coordination polymers were unintentionally obtained: {[Cd(µ3-EDTA)(Him)·Cd(Him)(H2O)2]·H2O}n (1), {[Cd(µ4-CDTA)(Hade)·Cd(Hade)2]}n (2), and {[Cd(µ3-EDTA)(H2O)·Cd(H9heade)(H2O)]·2H2O}n (3), having imidazole (Him), adenine ...
Jeannette Carolina Belmont-Sánchez, María Eugenia García-Rubiño, Antonio Frontera, Antonio Matilla-Hernández, Alfonso Castiñeiras, Juan Niclós-Gutiérrez   +5 more
doaj   +1 more source

Glibenclamide improves kidney and heart structure and function in the adenine-diet model of chronic kidney disease

, 2014
The development of chronic kidney disease (CKD) and associated cardiovascular disease involves free radical damage and inflammation. Addition of adenine to the diet induces inflammation followed by CKD and cardiovascular disease.
Diwan, Vishal, Brown, Lindsay, Gobe, Glenda   +2 more
core   +1 more source

Electrospun Wood‐Derived Biopolymers as Electrodes in Electrochemical Energy Storage Technologies

Advanced Functional Materials, EarlyView.
Electrospinning transforms wood‐derived cellulose and lignin into architecturally defined, binder‐free carbon electrodes with tuneable porosity and functionality. This review shows how fibre design enables decoupled charge and mass transport, enhancing performance across battery systems, while identifying key challenges in spinnability, scalability ...
Michael W. Thielke, Hattie R. Chisnall, Jesus Vazquez Chavez, Ana B. Jorge Sobrido   +3 more
wiley   +1 more source

Protonated nucleobases are not fully ionized in their chloride salt crystals and form metastable base pairs further stabilized by the surrounding anions

IUCrJ, 2018
This paper presents experimental charge-density studies of cytosinium chloride, adeninium chloride hemihydrate and guaninium dichloride crystals based on ultra-high-resolution X-ray diffraction data and extensive theoretical calculations.
Prashant Kumar, Malgorzata Katarzyna Cabaj, Aleksandra Pazio, Paulina Maria Dominiak   +3 more
doaj   +1 more source