The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT). [PDF]
Pharaoh G +12 more
europepmc +1 more source
Differences between the Reactivity of Endogenous and Exogenous Adenine Nucleotides in Mitochondria as Studied at Low Temperature [PDF]
H. W. Heldt, Martin Klingenberg
openalex +1 more source
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li +12 more
wiley +1 more source
Crosstalk between adenine nucleotide transporter and mitochondrial swelling: experimental and computational approaches. [PDF]
Chapa-Dubocq XR +3 more
europepmc +1 more source
Computational modelling of myocardial metabolism in patients with advanced heart failure
LV, left ventricular; LVAD, left ventricular assist device; LVEF, left ventricular ejection fraction. Abstract Aims Perturbations of myocardial metabolism and energy depletion are well‐established hallmarks of heart failure (HF), yet methods for their systematic assessment remain limited in humans.
Niklas Beyhoff +17 more
wiley +1 more source
Specific Interaction of Adenine Nucleotides with the Amino Acid Transport Mechanism in the Nuclear Membrane. [PDF]
Erkki Karjalainen +7 more
openalex +1 more source
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk +4 more
wiley +1 more source
A new adenine nucleotide transporter located in the ER is essential for maintaining the growth of Toxoplasma gondii. [PDF]
Li S +7 more
europepmc +1 more source

