Results 161 to 170 of about 370,851 (253)

Genome‐wide association study of morphometric and metabolic characteristics in European populations of the sugar kelp Saccharina latissima

Journal of Phycology, EarlyView.
Abstract The sugar kelp Saccharina latissima is a promising candidate for sustainable aquaculture in the North Atlantic and Northeast Pacific, but genetic improvement has been hindered by a limited understanding of the genetic basis of economically important traits.
Stéphane Mauger, Komlan Avia, Lucie Jaugeon, Paolo Ruggeri, Zofia Nehr, Ousseini Issaka Salia, Jérôme Coudret, Emilie Gouhier, Aurélien Baud, Stéphane Loisel, Antoine Fort, Ronan Sulpice, Christophe Destombe, Philippe Potin, J. Mark Cock, Myriam Valero   +15 more
wiley   +1 more source

Targeting the purine salvage pathway in in vitro models of cerebral ischemia [PDF]

An interruption of the blood supply to the brain, as occurs during ischemic stroke, results in a rapid decline of ATP levels and a subsequent loss of neuronal function and viability.
Zur Nedden, Stephanie
core  

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Gene Editing of Nicotiana benthamiana Architecture for Space‐Efficient Production of Recombinant Proteins in Closed Environments

Plant Biotechnology Journal, EarlyView.
ABSTRACT Indoor vertical farming (VF) offers practical advantages for the cultivation of plant protein bio‐factories including plant uniformity, product consistency, water/nutrient recycling and production cycles on a year‐round basis. Much progress has been achieved toward the development of innovative systems for artificial lighting, automated ...
Béatrice Giroux, Kristina LeBreux, Louis Feyzeau, Marie‐Claire Goulet, Charles Goulet, Dominique Michaud   +5 more
wiley   +1 more source

Gap‐Free Cannabis sativa Assemblies Reveal Post‐Polyploid Genome Remodelling and Refine the Evolution of Cannabinoid Synthase Genes

Plant Biotechnology Journal, EarlyView.
ABSTRACT Despite the therapeutic importance of cannabinoids, the scarcity of gap‐free Cannabis genomes has limited the dissection of the genetic and genomic basis of cannabinoid biosynthesis and genome evolution. Here, we generated two haplotype‐phased, gap‐free, gold‐standard assemblies and used them to investigate post‐polyploid genome remodelling ...
Jiangjiang Zhang, Chuchu Qin, Zhao Li, Lining Zhao, Ashok Biswas, Touming Liu, Mingbao Luan, Lin Li, Defang Li, Jianbin Yan   +9 more
wiley   +1 more source

Molecular Links Between Heat Stress and DNA Damage Response in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT Climate change poses a major threat to agricultural productivity and, consequently, to global food security. Among the consequences of climate change, heat stress (HS) has emerged as a critical factor limiting crop performance. This has stimulated extensive research over the past decade to elucidate the molecular and physiological mechanisms ...
Adrian Calves‐Ubach, Miriam Szurman‐Zubrzycka   +1 more
wiley   +1 more source

Perturbation of Spermine Homoeostasis Uncouples Hypersensitive Cell Death From Systemic Plant Immunity

Plant, Cell &Environment, EarlyView.
ABSTRACT Polyamines are key regulators of plant stress responses, yet their contribution to coordinating local immune responses with systemic immunity remains poorly understood. Here, we investigated how spermine (Spm) homeostasis influences local and systemic defence responses in Arabidopsis thaliana following inoculation with Pseudomonas syringae pv.
Jiaqi Zhao, Kostadin E. Atanasov, Olga Jauregui, Rubén Alcázar   +3 more
wiley   +1 more source

Cytokinins Promote Rust Susceptibility in Poplar by Suppressing Defence Signalling, Reducing Defence Accumulation and Reprogramming Primary Metabolism

Plant, Cell &Environment, EarlyView.
ABSTRACT Cytokinins (CKs), classically recognised as plant growth regulators, are increasingly implicated in plant‐microbe interactions. Studies in herbaceous plants suggest that CKs can function as signalling molecules with dual roles in plant defence, either restricting or facilitating pathogen infection.
Chhana Ullah, Ahalya Rajendran, Sarrin Shahadat, Michael Reichelt, Almuth Hammerbacher, Jonathan Gershenzon   +5 more
wiley   +1 more source

UV signature mutation hyperhotspots as genomic dosimeters

Photochemistry and Photobiology, EarlyView.
Recurrent UV signature mutations are a sensitive and specific indicator of sun exposure. UV signature mutations (C → T mutations at dipyrimidine sites) were quantified using Duplex Sequencing and a stringent mutation calling protocol to identify true low‐abundance mutations.
Vijay Menon, Alejandro García‐Ruiz, Susan Neveu, Brenda Cartmel, Leah M. Ferrucci, Meg Palmatier, Christine Ko, Kenneth Y. Tsai, Mio Nakamura, Sa Rang Kim, Michael Girardi, Karl Kornacker, Douglas E. Brash   +12 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source