Results 161 to 170 of about 892 (213)

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana   +2 more
wiley   +1 more source

Integrative simulation analysis of myocardial ischaemia–reperfusion injury

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A comprehensive mathematical model of ventricular myocyte was developed to gain insights into the mechanisms underlying cardiac ischaemia–reperfusion injury. The model integrates excitation–contraction (E–C) coupling, cytosolic and mitochondrial pH regulation, pH dependence of major E–C coupling components and cellular energy ...
Takao Shimayoshi   +2 more
wiley   +1 more source

Dynamic Surface‐Enhanced Raman Scattering Platform With Multiscale Nanostructural Engineering and Programmable Surface Energy for Artificial Intelligence‐Assisted Discrimination of Helicobacter pylori

open access: yesAdvanced Oncology, Volume 1, Issue 1, December 2026.
This study develops a dynamic surface‐enhanced Raman scattering (D‐SERS) platform integrating multiscale nanoparticle geometry, quantum dot coupling, surface‐energy programming, and a multilayer perceptron model for AI‐assisted classification. It enables ultrahigh sensitivity, noninvasive detection, and specific Helicobacter pylori identification.
Ming‐Chang Lu   +4 more
wiley   +1 more source

The Critical Role of Fractionated Urine Glycosaminoglycans in the Evaluation of Mucopolysaccharidosis Type II in Four Unrelated Families

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 2110-2117, September 2026.
ABSTRACT Since 2015, Ann and Robert H. Lurie Children's Hospital has performed diagnostic testing for infants who screen positive for mucopolysaccharidosis type II (MPS II) on the Illinois newborn screen. Preliminary diagnostic testing includes measurement of plasma iduronate‐2‐sulfatase enzyme activity and urinary glycosaminoglycan analysis, followed ...
Carly A. Rasmussen   +5 more
wiley   +1 more source

From Planar to Patterned: Structured Boron‐Doped Diamond Electrodes for Electrochemical Sensing

open access: yesAnalysis &Sensing, Volume 6, Issue 5, September 2026.
Structuring transforms boron‐doped diamond (BDD) from a planar electrode into a versatile sensing platform. This mini‐review surveys top‐down and bottom‐up fabrication routes, shows how structural design reshapes electrochemical behavior—enhancing current response, lowering oxidation potentials, and improving selectivity and stability—and then ...
Ghazaleh Kholafazadehastamal   +2 more
wiley   +1 more source

Editorial: Adenine nucleotides in immunity and inflammation

open access: yesFrontiers in Immunology
Müller, Christa E   +2 more
openaire   +4 more sources

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

open access: yesEquine Veterinary Journal, Volume 58, Issue 5, Page 1396-1412, September 2026.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka   +4 more
wiley   +1 more source

Turning up the heat: Can thermal therapy really protect muscle health in older adults?

open access: yes
Experimental Physiology, EarlyView.
Franck Brocherie   +2 more
wiley   +1 more source

Adenine Nucleotide Translocator in Heart

Molecular Genetics and Metabolism, 2000
The adenine nucleotide translocator (ANT) spans the inner mitochondrial membrane and facilitates exchange of cytosolic ADP for ATP within the mitochondrial matrix. ANT represents the most prominent single protein component of the inner mitochondrial membrane (1).
M A Portman
exaly   +3 more sources

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