Results 141 to 150 of about 102,948 (256)

Synthetic syntrophy for adenine nucleotide cross-feeding between metabolically active nanoreactors. [PDF]

Nat Nanotechnol
Heinen L, van den Noort M, King MS, Kunji ERS, Poolman B.   +4 more
europepmc   +1 more source

Mitochondria Isolated from Hearts Subjected to Ischemia/Reperfusion Benefit from Adenine Nucleotide Translocase 1 Overexpression. [PDF]

Membranes (Basel), 2021
Dörner A, Lynetskiy O, Euler G, Landmesser U, Schlüter KD, Heger J.   +5 more
europepmc   +1 more source

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

The FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero, Juan Luis Pacheco‐Garcia, Pavla Vankova, Dmitry Loginov, Isabel Quereda‐Moraleda, Jose Manuel Martin‐Garcia, Petr Man, Angel Luis Pey, Milagros Medina   +8 more
wiley   +1 more source

Aberrant activation of adenine nucleotide translocase 3 promotes progression and chemoresistance in multiple myeloma dependent on PINK1 transport. [PDF]

Int J Biol Sci
Hu K, Lai Y, Zhou J, Hu C, Guo S, Zhang H, Wang G, Zhang Q, Gao X, Wang Z, Liu Y, Feng Q, Yi H, Peng Y, Zhang Y, Wu X, Cai H, Shi J.   +17 more
europepmc   +1 more source

Skeletal muscle contraction kinetics and AMPK responses are modulated by the adenine nucleotide degrading enzyme AMPD1.

J Appl Physiol (1985), 2022
Hafen PS, Law AS, Matias C, Miller SG, Brault JJ.   +4 more
europepmc   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Adenine Nucleotide Translocators Control Kidney Metabolism and Lipid Handling. [PDF]

J Am Soc Nephrol
Sugahara S, Brooks CR.
europepmc   +1 more source

Adenine nucleotide translocation in spinach chloroplasts [PDF]

FEBS Letters, 1969
openaire   +3 more sources

Protective effects of extracellular vesicle‐like nanoparticles derived from Cannabis sativa adventitious roots against UVB‐induced damage in human keratinocytes

International Journal of Cosmetic Science, EarlyView.
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak, Su Hyun Park, Young Bae Ryu, Cha Young Kim, Jae Cheol Jeong, Woo Sik Kim   +5 more
wiley   +1 more source

Trans-Ned 19-Mediated Antagonism of Nicotinic Acid Adenine Nucleotide-Mediated Calcium Signaling Regulates Th17 Cell Plasticity in Mice. [PDF]

Cells, 2021
Nawrocki M, Lory N, Bedke T, Stumme F, Diercks BP, Guse AH, Meier C, Gagliani N, Mittrücker HW, Huber S.   +9 more
europepmc   +1 more source