Results 171 to 180 of about 185,291 (318)

Conformational change of adenine nucleotide translocase-1 mediates cisplatin resistance induced by EBV-LMP1. [PDF]

open access: yesEMBO Mol Med, 2021
Zhao L   +10 more
europepmc   +1 more source

Targeting aerobic glycolysis combats tyrosine kinase inhibitor resistance of hepatocellular carcinoma

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao   +6 more
wiley   +1 more source

The free-living flagellate Paratrimastix pyriformis uses a distinct mitochondrial carrier to balance adenine nucleotide pools.

open access: yesArch Biochem Biophys, 2023
Zítek J   +6 more
europepmc   +1 more source

High‐throughput generic single‐entity sequencing using droplet microfluidics

open access: yesiMeta, EarlyView.
We present Generic Single Entity Sequencing (GSE‐Seq), a droplet‐based workflow that generates monoclonal barcodes by one‐step PCR, performs dissolvable hydrogel‐enabled reactions for genome processing, and attaches barcodes during in‐droplet library preparation. Barcoded fragments are pooled and sequenced with PacBio long‐read sequencing. Barcodes are
Guoping Wang   +14 more
wiley   +1 more source

Site-specific acetylation of adenine nucleotide translocase 1 at lysine 23 in human muscle. [PDF]

open access: yesAnal Biochem, 2021
Finlayson J   +8 more
europepmc   +1 more source

New insights into applications of base editor in hereditary disorders

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy