Journal of Biological Engineering, 2017 Background In the yeast Saccharomyces cerevisiae, as in every eukaryotic organism, the mRNA 5′-untranslated region (UTR) is important for translation initiation. However, the patterns and mechanisms that determine the efficiency with which ribozomes bind
Jing Li +3 more
doaj +1 more source
Protection from inactivation of the adenine nucleotide translocator during hypoglycaemia-induced apoptosis by mitochondrial phospholipid hydroperoxide glutathione peroxidase [PDF]
, 2003 Hirotaka Imai +4 more
openalex +1 more source
The multiple ADP/ATP translocase genes are differentially expressed during human muscle development [PDF]
, 1992 The expression of the genes encoding the three isoforms of the human ADP/ATP translocase (T1, T2, and T3) has been analyzed at different stages of myogenic differentiation in an in vitro muscle cell system and compared with that in mature muscle.
Attardi, Giuseppe +3 more
core
Alu Overexpression Leads to an Increased Double‐Stranded RNA Signature in Dermatomyositis
Arthritis &Rheumatology, EarlyView.Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the noncoding genome in disease pathogenesis.
Rayan Najjar +2 more
wiley +1 more source
Scientific Argumentation as a Foundation for the Design of Inquiry-Based Science Instruction [PDF]
, 2013 Despite the attention that inquiry has received in science education research and policy, a coherent means for implementing inquiry in the classroom has been missing [1].
Brodsky, L., Falk, A.
core +1 more source
The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma
Chemistry &Biodiversity, EarlyView.ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha +4 more
wiley +1 more source
ChemBioChem, EarlyView.Aptamer selection‐derived RNA libraries targeting a DNA G‐quadruplex are profiled by both sequence abundance and three G‐quadruplex (G4)‐prediction tools. High G4 scores failed to match enrichment or binding, revealing that current G4 predictors alone cannot reliably prioritize functional aptamers and must be combined with abundance‐based and ...
Gefei Liu +3 more
wiley +1 more source
Catalog of 434 single-nucleotide polymorphisms (SNPs) in genes of the alcohol dehydrogenase, glutathione S-transferase, and nicotinamide adenine dinucleotide, reduced (NADH) ubiquinone oxidoreductase families [PDF]
, 2001 Aritoshi Iida +9 more
openalex +1 more source
[Adenine nucleotides in migraine].
Neurologia (Barcelona, Spain), 1991 Several studies have shown that migraine is associated with an abnormal platelet activation state, characterized by increased plasma levels of platelet BTG and PF4 proteins. Adenine nucleotides are contained in platelets as a part of the dense granules released during platelet activation.
R, Leira +5 more
openaire +1 more source
ChemMedChem, EarlyView.Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto +12 more
wiley +1 more source