Results 141 to 150 of about 644,554 (330)
Specific Interaction of Adenine Nucleotides with the Amino Acid Transport Mechanism in the Nuclear Membrane. [PDF]
, 1966 Erkki Karjalainen +7 more
openalex +1 more source
International Journal of Cancer, EarlyView.Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao +6 more
wiley +1 more source
High‐throughput generic single‐entity sequencing using droplet microfluidics
iMeta, EarlyView.We present Generic Single Entity Sequencing (GSE‐Seq), a droplet‐based workflow that generates monoclonal barcodes by one‐step PCR, performs dissolvable hydrogel‐enabled reactions for genome processing, and attaches barcodes during in‐droplet library preparation. Barcoded fragments are pooled and sequenced with PacBio long‐read sequencing. Barcodes are
Guoping Wang +14 more
wiley +1 more source
New insights into applications of base editor in hereditary disorders
Interdisciplinary Medicine, EarlyView.Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai +8 more
wiley +1 more source
Erratum: structural basis of AMPK regulation by adenine nucleotides and glycogen. [PDF]
Cell Res, 2015 Li X +10 more
europepmc +1 more source
Interdisciplinary Medicine, EarlyView.Although most cancer cells rely on aerobic glycolysis, Oxidative phosphorylation (OXPHOS) remains essential for their survival, proliferation, and metastasis. With the emergence of OXPHOS‐targeted drugs, its therapeutic potential is becoming increasingly evident.
Keke Chen +5 more
wiley +1 more source
Turkish Journal of Hematology, 2009 Objective: Variceal bleeding in cirrhosis is mainly due to platelet activation defect and secondary to coagulation defects. Secretion is an important process which release procoagulants for hemostasis.
Sam Annie-Jeyachristy +4 more
doaj
Adenine Nucleotides Attenuate Murine T Cell Activation Induced by Concanavalin A or T Cell Receptor Stimulation. [PDF]
Front Pharmacol, 2017 Shinohara Y, Tsukimoto M.
europepmc +1 more source
Phenothiazine Derivatives and Their Impact on the Apoptosis Processes: A Review
Journal of Applied Toxicology, EarlyView.ABSTRACT Phenothiazine derivatives have been used for decades as antipsychotic drugs in multiple mental health and physical conditions treatment (schizophrenia, mania in bipolar disorder, and psychosis). Epidemiological studies have shown that people with schizophrenia are less likely to suffer from cancer, which indicates the ability of antipsychotics
Michał Otręba +4 more
wiley +1 more source