Results 21 to 30 of about 686,474 (304)

CoCl2-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors

open access: yesBiomedicines, 2022
Chronic hypoxia drives vascular dysfunction by various mechanisms, including changes in mitochondrial respiration. Although endothelial cells (ECs) rely predominantly on glycolysis, hypoxia is known to alter oxidative phosphorylation, promote oxidative ...
Barbara Kutryb-Zajac   +6 more
doaj   +1 more source

Binding Group of Oligonucleotides on TiO 2 Surfaces: Phosphate Anions or Nucleobases? [PDF]

open access: yes, 2021
Although the immobilization of oligonucleotides (nucleic acid) on mineral surfaces is at the basis of different biotechnological applications, an atomistic understanding of the interaction of the nucleic acid components with the titanium dioxide surfaces has not yet been achieved.
arxiv   +1 more source

A liquid chromatography-tandem mass spectrometry based method for the quantification of adenosine nucleotides and NAD precursors and products in various biological samples

open access: yesFrontiers in Immunology, 2023
Adenine nucleotides (AN) are ubiquitous metabolites that regulate cellular energy metabolism and modulate cell communication and inflammation. To understand how disturbances in AN balance arise and affect cellular function, robust quantification ...
Johanna Hiefner   +5 more
doaj   +1 more source

On the verge of life: Distribution of nucleotide sequences in viral RNAs [PDF]

open access: yesBiosemiotics 14, No. 2, 253-269 (2021), 2020
The aim of the study is to analyze viruses using parameters obtained from distributions of nucleotide sequences in the viral RNA. Seeking for the input data homogeneity, we analyze single-stranded RNA viruses only. Two approaches are used to obtain the nucleotide sequences; In the first one, chunks of equal length (four nucleotides) are considered.
arxiv   +1 more source

Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle

open access: yesNature Communications, 2022
The mitochondrial ADP/ATP carrier transports adenine nucleotides. Here, authors identify the residues involved in substrate binding. One set forms the central substrate binding site and two asparagine/arginine pairs help to guide the substrates during ...
Vasiliki Mavridou   +5 more
doaj   +1 more source

Periodate-oxidized ATP stimulates the permeability transition of rat liver mitochondria [PDF]

open access: yes, 1998
Periodate-oxidized ADP (oADP) and periodate-oxidized ATP (oATP) stimulate the permeability transition in energized rat liver mitochondria measured as the Ca2+-efflux induced by Ca2+ and Pi.
Hagen, Thilo   +3 more
core   +1 more source

The evolution of purinergic receptors involved in recognition of a blood meal by hematophagous insects

open access: yesMemorias do Instituto Oswaldo Cruz, 1987
Many blood feeders use adenine nucleotides as cues for locating blood meal. Structure-activity relationship of adenine nucleotides as phagostimulants varies between closely-related species of blood feeders. It is suggested that a preexisting diverse pool
Rachel Galun
doaj   +1 more source

Nucleotides: Structure and Properties [PDF]

open access: yes, 2005
Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core   +1 more source

Development and application of LC/HRPS for quantification of adenine nucleotides, creatine phosphate, and creatine in sturgeon spermatozoa

open access: yesCzech Journal of Animal Science, 2017
The objective of this study was to investigate the applicability of liquid chromatography coupled with high resolution product scan (LC/HRPS) mass spectrometry for simultaneous quantification of adenine nucleotides, creatine phosphate, and creatine ...
Pavlo Fedorov   +5 more
doaj   +1 more source

Aspects of regulation of ketoglutarate dehydrogenase activity from ribbed mussel (Modiolus demissus) gills and cauliflower (Brassica oleracea) [PDF]

open access: yes, 1989
In ribbed bivalve mollusc gills, the enzyme ketoglutarate dehydrogenase is regulated by pH, ketoglutarate and adenine nucleotides but not by calcium ions.
Karam, George Antun
core   +2 more sources

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