Results 21 to 30 of about 117,318 (358)

Understanding the errors of SHAPE-directed RNA structure modeling [PDF]

open access: yes, 2011
Single-nucleotide-resolution chemical mapping for structured RNA is being rapidly advanced by new chemistries, faster readouts, and coupling to computational algorithms. Recent tests have shown that selective 2'-hydroxyl acylation by primer extension (SHAPE) can give near-zero error rates (0-2%) in modeling the helices of RNA secondary structure. Here,
Aviran S.   +53 more
arxiv   +3 more sources

A single nucleotide polymorphism produces different transcription profiles in <i>Campylobacter jejuni's cysM</i>. [PDF]

open access: yesFront Microbiol
A single nucleotide polymorphism (SNP) in the 126 bp untranslated region (UTR) directly upstream of Campylobacter jejuni’s cysM (cysteine synthase) results in significant effects on gene transcription.
Gunther Iv NW   +6 more
europepmc   +2 more sources

Fluorescence of Adenine and Inosine Nucleotides. [PDF]

open access: bronzeActa Chemica Scandinavica, 1963
Ingvar Lindqvist   +4 more
openaire   +3 more sources

Adenine Nucleotide and Nicotinamide Adenine Dinucleotide Measurements in Plants [PDF]

open access: yesCurrent Protocols in Plant Biology, 2020
AbstractAs the principal co‐factors of many metabolic pathways, the measurement of both adenine nucleotides and nicotinamide adenine dinucleotide provides important information about cellular energy metabolism. However, given their rapid and reversible conversion as well as their relatively low concentration ranges, it is difficult to measure these ...
Zhang, Youjun   +4 more
openaire   +6 more sources

CoCl2-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors

open access: yesBiomedicines, 2022
Chronic hypoxia drives vascular dysfunction by various mechanisms, including changes in mitochondrial respiration. Although endothelial cells (ECs) rely predominantly on glycolysis, hypoxia is known to alter oxidative phosphorylation, promote oxidative ...
Barbara Kutryb-Zajac   +6 more
doaj   +1 more source

A liquid chromatography-tandem mass spectrometry based method for the quantification of adenosine nucleotides and NAD precursors and products in various biological samples

open access: yesFrontiers in Immunology, 2023
Adenine nucleotides (AN) are ubiquitous metabolites that regulate cellular energy metabolism and modulate cell communication and inflammation. To understand how disturbances in AN balance arise and affect cellular function, robust quantification ...
Johanna Hiefner   +5 more
doaj   +1 more source

Binding Group of Oligonucleotides on TiO 2 Surfaces: Phosphate Anions or Nucleobases? [PDF]

open access: yes, 2021
Although the immobilization of oligonucleotides (nucleic acid) on mineral surfaces is at the basis of different biotechnological applications, an atomistic understanding of the interaction of the nucleic acid components with the titanium dioxide surfaces has not yet been achieved.
arxiv   +1 more source

On the verge of life: Distribution of nucleotide sequences in viral RNAs [PDF]

open access: yesBiosemiotics 14, No. 2, 253-269 (2021), 2020
The aim of the study is to analyze viruses using parameters obtained from distributions of nucleotide sequences in the viral RNA. Seeking for the input data homogeneity, we analyze single-stranded RNA viruses only. Two approaches are used to obtain the nucleotide sequences; In the first one, chunks of equal length (four nucleotides) are considered.
arxiv   +1 more source

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