Results 31 to 40 of about 708,526 (362)

RNA Capping by Transcription Initiation with Non-canonical Initiating Nucleotides (NCINs): Determination of Relative Efficiencies of Transcription Initiation with NCINs and NTPs

open access: yesBio-Protocol, 2017
It recently has been established that adenine-containing cofactors, including nicotinamide adenine dinucleotide (NAD+), reduced nicotinamide adenine dinucleotide (NADH), and 3’-desphospho-coenzyme A (dpCoA), can serve as ‘non-canonical initiating ...
Jeremy Bird   +2 more
doaj   +1 more source

Evaluation of functioning of mitochondrial electron transport chain with NADH and FAD autofluorescence [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2016
We prove the feasibility of evaluation of mitochondrial electron transport chain function in isolated mitochondria of smooth muscle cells of rats from uterus using fluorescence of NADH and FAD coenzymes. We found the inversely directed changes in FAD and
H. V. Danylovych
doaj   +1 more source

Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets

open access: yeseLife, 2015
MicroRNAs (miRNAs) direct post-transcriptional regulation of human genes by guiding Argonaute proteins to complementary sites in messenger RNAs (mRNAs) targeted for repression.
Nicole T Schirle   +4 more
doaj   +1 more source

Structural Basis of SARS-CoV-2 Polymerase Inhibition by Favipiravir

open access: yesThe Innovation, 2021
Summary: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has developed into an unprecedented global pandemic. Nucleoside analogs, such as Remdesivir and Favipiravir, can serve as the first-line broad-spectrum antiviral drugs ...
Qi Peng   +7 more
doaj   +1 more source

Recent advances in experimental techniques to probe fast excited-state dynamics in biological molecules in the gas phase : dynamics in nucleotides, amino acids and beyond [PDF]

open access: yes, 2013
In many chemical reactions, an activation barrier must be overcome before a chemical transformation can occur. As such, understanding the behaviour of molecules in energetically excited states is critical to understanding the chemical changes that these ...
Hadden DJ   +6 more
core   +1 more source

Synaptic Vesicle Protein 2 Binds Adenine Nucleotides*

open access: yesJournal of Biological Chemistry, 2008
Synaptic vesicle protein 2 (SV2) is required for normal calcium-regulated secretion of hormones and neurotransmitters. Neurons lacking the two most widely expressed isoforms, SV2A and SV2B, have a reduced readily releasable pool of synaptic vesicles ...
Jia Yao, S. Bajjalieh
semanticscholar   +1 more source

CapZyme-Seq: A 5′-RNA-Seq Method for Differential Detection and Quantitation of NAD-Capped and Uncapped 5′-Triphosphate RNA

open access: yesSTAR Protocols, 2020
Summary: Nucleoside-containing metabolites such as the oxidized and reduced forms of nicotinamide adenine dinucleotide (NAD+ and NADH), 3′-desphospho-coenzyme A (dpCoA), and flavin adenine dinucleotide (FAD) can be incorporated as RNA 5′ end caps by ...
Irina O. Vvedenskaya, Bryce E. Nickels
doaj   +1 more source

A membrane network of receptors and enzymes for adenine nucleotides and nucleosides

open access: yesBiochimica et Biophysica Acta, 2008
Most cells express more than one receptor plus degrading enzymes for adenine nucleotides or nucleosides, and cellular responses to purines are rarely compatible with the actions of single receptors.
K. Schicker   +7 more
semanticscholar   +1 more source

Substrate Nucleotide-Determined Non-Templated Addition of Adenine by Taq DNA Polymerase: Implications for PCR-Based Genotyping and Cloning

open access: yesBioTechniques, 1996
The Applied Biosystems PRISMTM fluorescence-based genotyping system as well as the Invitrogen TA Cloning® vector system are influenced by the tendency of Taq DNA polymerase to add an adenine nucleotide to the 3′ end of PCR products after extension ...
V.L. Magnuson   +8 more
doaj   +1 more source

Adenine, guanine and pyridine nucleotides in blood during physical exercise and restitution in healthy subjects

open access: yesEuropean Journal of Applied Physiology, 2010
Maximal physical exertion is accompanied by increased degradation of purine nucleotides in muscles with the products of purine catabolism accumulating in the plasma.
W. Dudzińska   +4 more
semanticscholar   +1 more source

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