The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. [PDF]
The yeast silent information regulator (Sir)2 protein links cellular metabolism and transcriptional silencing through its nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase activity.
Frye, Roy A +4 more
core
NAD+ enhancers as therapeutic agents in the cardiorenal axis
Cardiorenal diseases represent a complex interplay between heart failure and renal dysfunction, being clinically classified as cardiorenal syndromes (CRS).
Mariano Marín-Blázquez +4 more
doaj +1 more source
Dysregulation of NAD+ metabolism induces a Schwann cell dedifferentiation program [PDF]
The Schwann cell (SC) is the major component of the peripheral nervous system (PNS) that provides metabolic and functional support for peripheral axons. The emerging roles of SC mitochondrial function for PNS development and axonal stability indicate the
Hackett, Amber R +4 more
core +1 more source
Dissection of Nodule Development by Supplementation of \u3cem\u3eRhizobium leguminosarum\u3c/em\u3e biovar \u3cem\u3ephaseoli\u3c/em\u3e Purine Auxotrophs with 4-Aminoimidazole-5-Carboxamide Riboside [PDF]
Purine auxotrophs of Rhizobium leguminosarum biovar phaseoli CFN42 elicit uninfected pseudonodules on bean (Phaseolus vulgaris L.). Addition of 4-aminoimidazole-5-carboxamide (AICA) riboside to the root medium during incubation of the plant with these ...
Newman, Jeffrey D. +2 more
core +1 more source
Kidney Transplant Outcomes in Patients With Adenine Phosphoribosyltransferase Deficiency. [PDF]
Runolfsdottir HL +8 more
europepmc +1 more source
Nuclear Translocation of b-Catenin during Mesenchymal Stem Cells Differentiation into Hepatocytes Is Associated with a Tumoral Phenotype [PDF]
Wnt/b-catenin pathway controls biochemical processes related to cell differentiation. In committed cells the alteration of this pathway has been associated with tumors as hepatocellular carcinoma or hepatoblastoma.
Almadén Peña, Yolanda +10 more
core
Age- and AD-related redox state of NADH in subcellular compartments by fluorescence lifetime imaging microscopy. [PDF]
Nicotinamide adenine dinucleotide (reduced form: NADH) serves as a vital redox-energy currency for reduction-oxidation homeostasis and fulfilling energetic demands.
Brewer, Gregory J +2 more
core +1 more source
Die Funktion des Responseregulators ARR2 in der Entwicklung von Arabidopsis thaliana [PDF]
In dieser Arbeit konnte mittels physiologischer Experimente, Expressionsanalysen, Phosphorylierungsassays und Transaktivierungsanalysen eine komplexe Funktion von ARR2 in verschiedenen Signaltransduktionswegen von Arabidopsis aufgedeckt werden.
Haß, Claudia
core
Nicotinamide adenine dinucleotide (NAD)+ serves as a crucial coenzyme in numerous essential biological reactions, and its cellular availability relies on the activity of the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed salvage pathway.
Jae Woo Park +17 more
doaj +1 more source

