Results 41 to 50 of about 6,350 (165)
Dihydroxyadenine crystal-induced nephropathy presenting with rapidly progressive renal failure
Kidney Research and Clinical Practice, 2018 Adenine phosphoribosyltransferase enzyme deficiency is a rare, autosomal recessive disorder. It is a disease limited to the renal system and usually presents with urolithiasis.
Ritu Verma +3 more
doaj +1 more source
BluB/CobT2 fusion enzyme activity reveals mechanisms responsible for production of active form of vitamin B 12 by Propionibacterium freudenreichii [PDF]
, 2015 Background Propionibacterium freudenreichii is a food grade bacterium that has gained attention as a producer of appreciable amounts of cobalamin, a cobamide with activity of vitamin B 12 .
Chamlagain, Bhawani Shankar +7 more
core +1 more source
Adenine transport and binding in cultured mammalian cells deficient in adenine phosphoribosyltransferase. [PDF]
Molecular and Cellular Biology, 1983 Rapid kinetic techniques were employed to measure the transport of adenine in adenine phosphoribosyltransferase-deficient L929 and Chinese hamster ovary (CHO) cells in zero-trans entry and exit and equilibrium exchange procedures. The kinetic parameters of transport were computed by fitting appropriate integrated rate equations to time courses of ...
M B Puziss +2 more
openaire +3 more sources
Emerging therapeutic roles for NAD+ metabolism in mitochondrial and age-related disorders [PDF]
, 2016 Nicotinamide adenine dinucleotide (NAD(+)) is a central metabolic cofactor in eukaryotic cells that plays a critical role in regulating cellular metabolism and energy homeostasis. NAD(+) in its reduced form (i.e.
Sarika Srivastava
core +1 more source
Urology Case Reports, 2023 The incidence of nephrolithiasis in children ranges from 5 to 10% in developing countries. Etiology of nephrolithiasis in children remains largely unknown, so metabolic evaluation is indicated in all case, because of potential morbidity and recurrence ...
Rizky Ramdhani +6 more
doaj
Animal models of pediatric chronic kidney disease. Is adenine intake an appropriate model? [PDF]
, 2015 Pediatric chronic kidney disease (CKD) has peculiar features. In particular, growth impairment is a major clinical manifestation of CKD that debuts in pediatric age because it presents in a large proportion of infants and children with CKD and has a ...
Claramunt, Débora +4 more
core +4 more sources
Renal stones in two children with two rare etiologies
Saudi Journal of Kidney Diseases and Transplantation, 2018 The incidence of urolithiasis in children has shown an increase in recent years which may be attributed to changing dietary patterns, sedentary lifestyles, and obesity.
Gurinder Kumar, Rami Raad AlAni
doaj +1 more source
PLoS ONE, 2022 AMPK can activate nicotinamide phosphoribosyltransferase (NAMPT), increasing the ratio of oxidized nicotinamide adenine dinucleotide (NAD+)/reduced nicotinamide adenine dinucleotide (NADH) ratio, leading to the activation of the energy receptor SIRT1 ...
Yayuan Yang +6 more
doaj +2 more sources
Frontiers in Behavioral Neuroscience, 2022 To establish a mouse model of weak depression, we raised 6-week-old C57BL/6N mice in single (SH) or group housing (GH) conditions for 2 weeks. The SH group showed less social interaction with stranger mice, learning disability in behavioral tests, and ...
Kousuke Shimada +12 more
doaj +1 more source
Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts
Advanced Science, EarlyView.Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian +10 more
wiley +1 more source