Results 51 to 60 of about 13,488 (222)
Dihydroxyadenine crystal-induced nephropathy presenting with rapidly progressive renal failure
Kidney Research and Clinical Practice, 2018 Adenine phosphoribosyltransferase enzyme deficiency is a rare, autosomal recessive disorder. It is a disease limited to the renal system and usually presents with urolithiasis.
Ritu Verma +3 more
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Kinetic Studies of Adenine Phosphoribosyltransferase
Journal of Biological Chemistry, 1966 Abstract The mechanism of reaction of adenine phosphoribosyl-transferase from Ehrlich ascites tumor cells was investigated kinetically by initial velocity and product inhibition studies. The data are consistent with a mechanism in which 5-phosphoribosylpyrophosphate reacts with the enzyme to form an intermediate, presumably an enzyme-ribose 5-phosphate
M, Hori, J F, Henderson
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Adenine Phosphoribosyltransferase Mutants in Saccharomyces cerevisiae [PDF]
Microbiology, 1984 Mutants of Saccharomyces cerevisiae deficient in adenine phosphoribosyltransferase (A-PRT, EC 2,4,2,7) have been isolated following selection for resistance to 8-azaadenine in a prototrophic strain carrying the ade4-su allele of the gene coding for amidophosphoribosyltransferase (EC 2,4,2,14). The mutants were recessive and defined a single gene, apt1.
R A, Woods +3 more
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Sirtuin 1 in rat orthotopic liver transplantation: An IGL-1 preservation solution approach [PDF]
, 2015 © The Author(s) 2015. AIM: To investigate the possible involvement of Sirtuin 1 (SIRT1) in rat orthotopic liver transplantation (OLT), when Institute Georges Lopez 1 (IGL-1) preservation solution is enriched with trimetazidine (TMZ).
Abdennebi, Hassen B. +8 more
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Improved cytotoxic effects of Salmonella-producing cytosine deaminase in tumour cells [PDF]
, 2016 This is an open access article under the terms of the Creative Commons Attribution License.In order to increase the cytotoxic activity of a Salmonella strain carrying a salicylate-inducible expression system that controls cytosine deaminase production ...
Camacho, Eva María +4 more
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, 2017 Constraint-based modeling for genome-scale metabolic networks has emerged in the last years as a promising approach to elucidate drug targets in cancer.
Agirre, Xabier +13 more
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Renal stones in two children with two rare etiologies
Saudi Journal of Kidney Diseases and Transplantation, 2018 The incidence of urolithiasis in children has shown an increase in recent years which may be attributed to changing dietary patterns, sedentary lifestyles, and obesity.
Gurinder Kumar, Rami Raad AlAni
doaj +1 more source
Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse [PDF]
, 2013 Closure of the neural tube during embryogenesis is a crucial step in development of the central nervous system. Failure of this process results in neural tube defects, including spina bifida and anencephaly, which are among the most common birth defects ...
Copp, AJ +4 more
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Asia-Pacific Journal of Chemical Engineering, EarlyView.ABSTRACT Greenhouse gas (GHG) emissions have emerged as one of the most critical drivers of climate change; this is primarily due to high concentrations and long atmospheric life of carbon dioxide (CO2). For a significant amount of time, various biological processes such as microalgal cultivation, cyanobacterial systems, photosynthetic microorganisms ...
Sadhana Semwal, Harish Chandra Joshi
wiley +1 more source
Efficient one-pot synthesis, molecular docking and in silico ADME prediction of bis-(4-hydroxycoumarin-3-yl) methane derivatives as antileishmanial agents [PDF]
, 2015 Bis-(4-hydroxycoumarin-3-yl) methane derivatives 3(a-l) were synthesized from 4-hydroxycoumarin and substituted aromatic aldehydes using succinimide-N-sulfonic acid as catalyst and evaluated for their in vitro antileishmanial activity against ...
Khan, Firoz A. Kalam +3 more
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