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Adenovirus–Adeno-Associated Virus Hybrid for Large-Scale Recombinant Adeno-Associated Virus Production

Human Gene Therapy, 2009
Recombinant adeno-associated virus (rAAV) holds promise for applications in gene therapy. Advances in clinical studies of rAAV-based gene therapeutics have generated an encouraging momentum in the field of gene therapy; however, one of the major obstacles to the eventual clinical success of rAAV-mediated gene therapy is the need for large-scale ...
Hongwei, Zhang   +4 more
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Adeno-Associated Virus (AAV) Vectors in the CNS

Current Gene Therapy, 2005
Adeno-associated virus (AAV) vectors exhibit a number of properties that have made this vector system an excellent choice for both CNS gene therapy and basic neurobiological investigations. In vivo, the preponderance of AAV vector transduction occurs in neurons where it is possible to obtain long-term, stable gene expression with very little ...
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Generation of Recombinant Adeno-Associated Virus

2003
Adeno-associated virus (AAV) was discovered about 30 yr ago as a contaminant of adenovirus preparations. Since its discovery, researchers have described many unique characteristics of AAV biology that have made it attractive as a potential vector for gene therapy.
openaire   +2 more sources

The Interplay between Adeno-Associated Virus and Its Helper Viruses

Viruses, 2020
Cornel Fraefel   +2 more
exaly  

Adeno-associated virus

Advances in Anatomic Pathology, 1994
openaire   +1 more source

Targeted Integration by Adeno-Associated Virus

2003
Matthew D, Weitzman   +3 more
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Adeno-associated Virus Serotypes: Vector Toolkit for Human Gene Therapy

Molecular Therapy, 2006
Aravind Asokan, R Jude Samulski
exaly  

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