Results 221 to 230 of about 70,372 (263)
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Human Gene Therapy, 2009
Recombinant adeno-associated virus (rAAV) holds promise for applications in gene therapy. Advances in clinical studies of rAAV-based gene therapeutics have generated an encouraging momentum in the field of gene therapy; however, one of the major obstacles to the eventual clinical success of rAAV-mediated gene therapy is the need for large-scale ...
Hongwei, Zhang +4 more
openaire +2 more sources
Recombinant adeno-associated virus (rAAV) holds promise for applications in gene therapy. Advances in clinical studies of rAAV-based gene therapeutics have generated an encouraging momentum in the field of gene therapy; however, one of the major obstacles to the eventual clinical success of rAAV-mediated gene therapy is the need for large-scale ...
Hongwei, Zhang +4 more
openaire +2 more sources
Adeno-Associated Virus (AAV) Vectors in the CNS
Current Gene Therapy, 2005Adeno-associated virus (AAV) vectors exhibit a number of properties that have made this vector system an excellent choice for both CNS gene therapy and basic neurobiological investigations. In vivo, the preponderance of AAV vector transduction occurs in neurons where it is possible to obtain long-term, stable gene expression with very little ...
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Generation of Recombinant Adeno-Associated Virus
2003Adeno-associated virus (AAV) was discovered about 30 yr ago as a contaminant of adenovirus preparations. Since its discovery, researchers have described many unique characteristics of AAV biology that have made it attractive as a potential vector for gene therapy.
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The Interplay between Adeno-Associated Virus and Its Helper Viruses
Viruses, 2020Cornel Fraefel +2 more
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Adeno-Associated Virus Genome Interactions Important for Vector Production and Transduction
Human Gene Therapy, 2020Matthew Weitzman
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Targeted Integration by Adeno-Associated Virus
2003Matthew D, Weitzman +3 more
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Adeno-associated Virus Serotypes: Vector Toolkit for Human Gene Therapy
Molecular Therapy, 2006Aravind Asokan, R Jude Samulski
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