Results 291 to 300 of about 116,785 (352)

Identification and Phylogenetic Characterisation of Novel Adeno‐Associated Virus Capsids in Non‐Human Primate Tissues

Liyu Zhu, Kai Xu, Yali Ding, Kailun Liu, Jing Liu, Zongren Hou, Rui Niu, Ning Yang, Hualing Qin, Baoyang Hu, Ying Zhang, Wei Li   +11 more
openalex   +1 more source

Use of cesium chloride density gradient ultracentrifugation for the purification and characterization of recombinant adeno-associated virus. [PDF]

Eur Biophys J
Hirohata K, Kino S, Yamane T, Bandoh K, Bamba T, Sternisha SM, Torisu T, Fukuhara M, Yamaguchi Y, Uchiyama S.   +9 more
europepmc   +1 more source

Targeting ROCK1/YAP1 Axis Ameliorates Inflammation‐Induced Prostatic Hyperplasia via Stabilising SIRT1‐Dependent Mitochondrial Dynamics

Cell Proliferation, EarlyView.
Prostate‐specific YAP1 overexpression induces pathological BPH phenogenesis. Targeting ROCK1/YAP1 with fasudil and verteporfin alleviates inflammatory BPH lesions. YAP1 orchestrates mitochondrial dysfunction and oxidative stress via suppressing SIRT1 function.
Dongxu Lin, Pengyu Wei, Mengyang Zhang, Kang Li, Lina Li, Zhipeng Li, Changcheng Luo, Wenbo Kuang, Kai Cui, Zhong Chen   +9 more
wiley   +1 more source

<i>In vivo</i> adeno-associated virus-mediated LDLR/PCSK9 intervention for familial hypercholesterolemia. [PDF]

Genes Dis
Han Z, Tan C, Ai J, Zhu Y.
europepmc   +1 more source

Recombinant Adeno-associated Virus Vectors

Japanese Journal of Thrombosis and Hemostasis, 1998
openaire   +2 more sources

Dysregulation of Rho‐Associated Coiled‐Coil Protein Kinase1 Depletes Neural Stem Cell Pool and Impairs Hippocampal Neurogenesis After Traumatic Brain Injury

Cell Proliferation, EarlyView.
Following TBI, hippocampal neurogenesis in mice is impaired and affects cognitive function. This impairment is associated with the upregulation of p‐AKT/AKT mediated by ROCK1. ABSTRACT Traumatic brain injury (TBI) represents a global health burden, often resulting in persistent neurological deficits due to impaired hippocampal neurogenesis ...
Chaoqun Yao, Long Jin, Jun Zhong, Qianying Huang, Zhongwei Bao, Shaolong Zhou, Chaohua Wang, Huanhuan Li, Xiaowei Yuan, Zhen Wang, Ning Du, Jingxuan Yu, Huanran Chen, Xuyang Zhang, Hongfei Ge, Jianheng Wu   +15 more
wiley   +1 more source

Overexpression of interleukin-4 using adeno-associated virus is a potential strategy to enhance bone regeneration. [PDF]

JBMR Plus
Kim H, Kim KH, Kang L, Seol YJ, Chung SH, Park SY.   +5 more
europepmc   +1 more source

Ageing‐Dependent Thyroid Hormone Receptor α Reduction Activates IP3R1‐Meditated Ca2+ Transfer in MAM and Exacerbates Skeletal Muscle Atrophy in Mice

Cell Proliferation, EarlyView.
During skeletal muscle ageing, down‐regulation of TRα expression activates IP3R1 transcriptional expression, promotes MAM calcium transport, triggers mitochondrial calcium overload and apoptosis, leading to skeletal muscle atrophy. Restoring TRα expression can improve IP3R1‐mediated mitochondrial calcium overload and apoptosis in ageing skeletal muscle
Runqing Shi, Yusheng Zhang, Gong Chen, Jiru Zhang, Jing Liu, Hao Zhu, Minne Sun, Yu Duan   +7 more
wiley   +1 more source

Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9 [PDF]

, 2019
Curiel, David T, Kashentseva, Elena, Lauron, Elvin J, Lu, Zhi Hong, Stephens, Calvin J, Yokoyama, Wayne M   +5 more
core   +1 more source