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Adeno-Associated Virus (AAV) Vectors in the CNS
Current Gene Therapy, 2005Adeno-associated virus (AAV) vectors exhibit a number of properties that have made this vector system an excellent choice for both CNS gene therapy and basic neurobiological investigations. In vivo, the preponderance of AAV vector transduction occurs in neurons where it is possible to obtain long-term, stable gene expression with very little ...
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ADENOVIRUS, ADENO-ASSOCIATED VIRUS AND KAWASAKI DISEASE
The Pediatric Infectious Disease Journal, 2005Clinical similarities and shared seasonality suggested a relationship between adenovirus infection and Kawasaki disease. We performed adenovirus serology and quantitative polymerase chain reaction for both adenovirus and adeno-associated virus in patients with acute Kawasaki disease.
Hiroko, Shike +6 more
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Genome localization of adeno-associated virus RNA
Journal of Virology, 1976In previous work, linear duplex molecules of adeno-associated virus, type 2 (AAV2), DNA were cleaved with the restriction endonucleases R-EcoRI, R-HindII, and R-HindIII. The physical order of the specific fragments obtained was deduced and oriented with respect to the DNA strand polarity and the direction of transcription. Stable AAV RNA is transcribed
B J, Carter +3 more
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Generation of Recombinant Adeno-Associated Virus
2003Adeno-associated virus (AAV) was discovered about 30 yr ago as a contaminant of adenovirus preparations. Since its discovery, researchers have described many unique characteristics of AAV biology that have made it attractive as a potential vector for gene therapy.
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Chromatography-Based Purification of Adeno-Associated Virus
2008Virus-mediated gene transfer shows great potential as a therapeutic strategy for the management of various inherited and acquired human diseases. Among the current viral vectors, adeno-associated virus (AAV) has become the vector of choice for numerous gene therapy applications. As AAV-based vectors approach the clinic, the need for scalable methods of
Richard H, Smith +2 more
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The Interplay between Adeno-Associated Virus and Its Helper Viruses
Viruses, 2020Anita F Meier +2 more
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Optimizing Adeno-Associated Virus Serotype 9 for Studies of Cardiac Chamber–Specific Gene Regulation
Circulation, 2021Alina S Bilal +2 more
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Targeted Integration by Adeno-Associated Virus
2003Matthew D, Weitzman +3 more
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A Precise Chemical Strategy To Alter the Receptor Specificity of the Adeno‐Associated Virus
Angewandte Chemie - International Edition, 2016Rachel E Kelemen +2 more
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