Results 71 to 80 of about 1,279,856 (386)
Pancreatic Ductal Adenocarcinoma: Current and Evolving Therapies
International Journal of Molecular Sciences, 2017 Pancreatic ductal adenocarcinoma (PDAC), which constitutes 90% of pancreatic cancers, is the fourth leading cause of cancer-related deaths in the world.
A. Adamska, A. Domenichini, M. Falasca
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]
, 2006 We report a multiwavelength (X-ray, ultraviolet/optical/infrared, radio) analysis of the relativistic tidal disruption event candidate Sw J2058+05 from 3 months to 3 yr post-discovery in order to study its properties and compare its behavior with that of
Bower, Geoffrey C. +15 more
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Small Bowel Adenocarcinoma Presenting with Brain Metastasis
Turkish Journal of Colorectal Disease, 2020 Although the small bowel (SB) comprises majority of the length of alimentary tract and its surface mucosal area, adenocarcinoma of SB is rare in comparison to other gastrointestinal malignancies.
Isra Al Jorani, Özgen Işık
doaj +1 more source
Periacinar clefting and p63 immunostaining in prostatic intraepithelial neoplasia and prostatic carcinoma [PDF]
, 2006 The aim of the present study was to correlate the presence and extent of retraction clefting and the expression of p63 in neoplastic glands and glands with prostatic intraepithelial neoplasia (PIN) in needle core biopsies.
Belicza, Mladen +5 more
core +1 more source
Mucinous colorectal adenocarcinoma: clinical pathology and treatment options
Cancer Communications, 2019 Mucinous colorectal adenocarcinoma is a distinct subtype of colorectal cancer (CRC) characterized by the presence of abundant extracellular mucin which accounts for at least 50% of the tumor volume.
C. Luo, S. Cen, Guojun Ding, Wei Wu
semanticscholar +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Adenocarcinoma do saco endolinfático: relato de caso
Arquivos de Neuro-Psiquiatria, 2002 Apresenta-se um caso de adenocarcinoma do saco endolinfático e revê-se a literatura. O quadro clínico manifestou-se por tonteira e perda progressiva da audição consequentes a tumor do saco endolinfático.
Silveira Roberto Leal +3 more
doaj
Cancer Management and Research, 2022 Ramin Saadaat,1 Jamshid Abdul-Ghafar,1 Ahmed Maseh Haidary,1 Nooria Atta,2 Tazeen Saeed Ali3 1Department of Pathology and Clinical Laboratory, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan; 2Department of Gynecology and ...
Saadaat R +4 more
doaj