International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising. [PDF]
, 2005 Lung cancer rates have peaked among men in many areas of the world, but rates among women continue to rise. Most lung cancers are squamous cell carcinoma, small cell carcinoma, or adenocarcinoma; trends vary according to type.
Bray, Freddie +3 more
core +1 more source
MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma [PDF]
, 2018 Background The high incidence and mortality of lung tumours is a major health problem. Therefore, the identification both of biomarkers predicting efficacy for therapies in use and of novel efficacious therapeutic agents is crucial to increase patient ...
Carnero Moya, Amancio +5 more
core +1 more source
Cardiac Tamponade Secondary to Metastasis from Adenocarcinoma of the Parotid Gland [PDF]
, 2003 BACKGROUND: Metastatic involvement of pericardium producing cardiac tamponade is rare. When occurs it is mainly from the lung, breast and the neoplasms of the lymphoreticular system.
Barbetakis, Nikolaos G +5 more
core +4 more sources
Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics [PDF]
, 2016 Therapeutic manipulation of the gasotransmitter hydrogen sulfide (H(2)S) has recently been proposed as a novel targeted anticancer approach. Here we show that human lung adenocarcinoma tissue expresses high levels of hydrogen sulfide (H(2)S) producing ...
Druzhyna, Nadiya +7 more
core +1 more source
Pan-cancer classifications of tumor histological images using deep learning [PDF]
, 2020 Histopathological images are essential for the diagnosis of cancer type and selection of optimal treatment. However, the current clinical process of manual inspection of images is time consuming and prone to intra- and inter-observer variability. Here we
Caruana, Dennis +8 more
core +1 more source
Dry Small Pleural Dissemination of Adenocarcinoma of the Lung Preoperatively Detected by PET/CT: A Report of Two Cases [PDF]
, 2008 Dry pleural dissemination in non-small cell lung cancer, defined as solid pleural metastasis of lung cancer without pleural eff usion, is a condition occurring in T4 lung cancer.
Aoe, Motoi +6 more
core +1 more source
Evolution of lung adenocarcinoma from preneoplasia to invasive adenocarcinoma
Cancer Medicine, 2022 AbstractObjectiveMutations in driver genes contribute to the development and progression of lung adenocarcinoma (LUAD). However, in the dynamic evolutionary process from adenocarcinoma in situ (AIS) to minimally invasive adenocarcinoma (MIA) and eventually to invasive adenocarcinoma (IAC), the role of driver genes is currently unclear. This study aimed
Jianfei Zhu +8 more
openaire +3 more sources
EGFR Mutation Status in Uighur Lung Adenocarcinoma Patients
Chinese Journal of Lung Cancer, 2013 Background and objective Epidermal growth factor receptor (EGFR), a transmembrane protein, is a member of the tyrosine kinase family. Gefitinib, an EGFR tyrosine-kinase inhibitors, has shown a high response rate in the treatment of lung cancer in ...
Li SHAN +4 more
doaj +1 more source
Progesterone/Org inhibits lung adenocarcinoma cell growth via membrane progesterone receptor alpha
Thoracic Cancer, 2020 Background The aim of this study was to determine whether progesterone could inhibit the growth of lung adenocarcinoma cells via membrane progesterone receptor alpha (mPRα) and elucidate its potential mechanism.
Jian Xiao +7 more
doaj +1 more source
Hepatoid adenocarcinoma of the lung
Autopsy and Case Reports, 2013 Lung adenocarcinomas with a mixture of tubular or papillary pattern, sheet-like or trabecular architecture, eosinophilic cytoplasm with centrally located nuclei and alpha-fetoprotein-producing cells have been described as hepatoid adenocarcinomas.
Livia Barreira Cavalcante +3 more
openaire +3 more sources