Results 41 to 50 of about 329,845 (308)

Overexpression of RhoV Promotes the Progression and EGFR-TKI Resistance of Lung Adenocarcinoma

open access: yesFrontiers in Oncology, 2021
BackgroundThe Rho GTPase family with ~20 member genes play central roles in a wide variety of cellular processes and tumor cell migration and metastasis.
Hongjin Chen   +12 more
doaj   +1 more source

Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma [PDF]

open access: yes, 2017
Hedgehog (HH) pathway plays an important role in embryonic development, but is largely inactive in adult except for tissue repair. Aberrant activation of HH pathway has been found in a variety of cancer types.
何肇基   +1 more
core   +1 more source

FAM83A is highly expressed in lung adenocarcinoma tissues and promotes invasion and metastasis of lung adenocarcinoma cells

open access: yesZhongguo aizheng zazhi, 2020
Background and purpose: A growing number of studies have shown that family with sequence similarity 83 member A (FAM83A) is correlated with the invasion and metastasis of tumor, however, the role of FAM83A in lung adenocarcinoma is unclear.
王晓栋   +6 more
doaj  

Papillary Adenocarcinoma: A Rare Subtype of Lung Adenocarcinoma

open access: yesCureus, 2023
Papillary adenocarcinoma (PA) of the lung is a specific form of lung cancer characterized by papillary structures in tumor cells. This type of cancer is relatively rare and has distinct pathological and radiological features that differentiate it from other types of lung adenocarcinomas.
Thouil, Afaf   +4 more
openaire   +2 more sources

Prognostic factors of acinar- or papillary-predominant adenocarcinoma of the lung [PDF]

open access: yes, 2019
OBJECTIVE: Histologic types are correlated with prognosis in lung adenocarcinoma. The acinar/papillary type is most common, although this group comprises heterogeneous tumor types. However, the prognostic factors in this group have not been well studied.
김문식, 김경아, 심효섭
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

TENET 2.0: Identification of key transcriptional regulators and enhancers in lung adenocarcinoma.

open access: yesPLoS Genetics, 2020
Lung cancer is the leading cause of cancer-related death and lung adenocarcinoma is its most common subtype. Although genetic alterations have been identified as drivers in subsets of lung adenocarcinoma, they do not fully explain tumor development ...
Daniel J Mullen   +8 more
doaj   +1 more source

XXYLT1 methylation contributes to the occurrence of lung adenocarcinoma

open access: yesMedicine, 2021
Abstract Background: There is evidence that DNA methylation play major roles in lung cancer. In our previously study, C3 or f21 , also referred to as XXYLT1, rs2131877 polymorphism is associated with a reduced risk of lung adenocarcinoma. So, we explored the role of XXYLT1 methylation in lung adenocarcinoma.
Zeng, Hui   +3 more
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy