Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer. [PDF]
, 2015 The cancer stem cell hypothesis, that a small population of tumour cells are responsible for tumorigenesis and cancer progression, is becoming widely accepted and recent evidence has suggested a prognostic and predictive role for such cells. Intra-tumour
Banerji, CR +11 more
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Marantic Endocarditis and Lung Adenocarcinoma with Brain Metastasis: A Diagnostic Conundrum [PDF]
, 2023 Neurological symptoms such as headache and blurring of vision could be a manifestation of an underlying lung adenocarcinoma. The objective of this case report is to unveil the possible differentials and processes involved in the diagnosis of marantic ...
Anant Patil +5 more
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Putative effectors for prognosis in lung adenocarcinoma are ethnic and gender specific [PDF]
, 2017 Lung adenocarcinoma possesses distinct patterns of EGFR/KRAS mutations between East Asian and Western, male and female patients. However, beyond the well-known EGFR/KRAS distinction, gender and ethnic specific molecular aberrations and their effects on ...
Woolston, Andrew;Sintupisut, Nardnisa;Lu, Tzu-Pin;Lai, Liang-Chuan;Tsai, Mong-Hsun;Chuang, Eric Y.;Yeang, Chen-Hsiang +1 more
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Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China. [PDF]
, 2013 A recent genome-wide association study of lung cancer among never-smoking females in Asia demonstrated that the rs2736100 polymorphism in the TERT-CLPTM1L locus on chromosome 5p15.33 was strongly and significantly associated with risk of adenocarcinoma ...
Xiang, Y +67 more
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An EGFR-mutant lung adenocarcinoma that transformed into small-cell lung cancer. A case report [PDF]
, 2022 Background. Transformation of EGFR (epidermal growth factor receptor) - mutant non-small cell lung cancer (NSCLC) into small-cell lung cancer (SCLC) is one mechanism of resistance to tyrosine kinase inhibitor (TKI) treatment, seen in approximately 3-10 ...
Dalibor Ondrus +7 more
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EGFR Mutation Status in Uighur Lung Adenocarcinoma Patients
Chinese Journal of Lung Cancer, 2013 Background and objective Epidermal growth factor receptor (EGFR), a transmembrane protein, is a member of the tyrosine kinase family. Gefitinib, an EGFR tyrosine-kinase inhibitors, has shown a high response rate in the treatment of lung cancer in ...
Li SHAN +4 more
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Hepatoid adenocarcinoma of the lung
Autopsy and Case Reports, 2013 Lung adenocarcinomas with a mixture of tubular or papillary pattern, sheet-like or trabecular architecture, eosinophilic cytoplasm with centrally located nuclei and alpha-fetoprotein-producing cells have been described as hepatoid adenocarcinomas.
Livia Barreira Cavalcante +3 more
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The role of spread through air spaces (STAS) in lung adenocarcinoma prognosis and therapeutic decision making. [PDF]
, 2020 Spread through air spaces (STAS) was included as a novel pattern of invasion in lung adenocarcinoma by the World Health Organization in 2015. Since then, multiple studies have investigated the association of STAS with clinicopathological and molecular ...
Toki, MI, Syrigos, KN, Harrington, K
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The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients [PDF]
, 2017 Introduction: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are associated with favorable response in EGFR mutant lung cancer.
Wu, Shang-Gin;Liu, Yi-Nan;Tsai, Meng-Feng;Chang, Yih-Leong;Yu, Chong-Jen;Yang, Pan-Chyr;Yang, James Chih-Hsin;Wen, Yueh-Feng;Shih, Jin-Yuan +1 more
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GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma
BMC Cancer, 2018 Background Lung adenocarcinoma is the most common type of lung cancer and one of the most lethal and prevalent cancers. Aberrant glycosylation was common and essential in tumorigenesis, with fucosylation as one of the most common types disrupted in ...
Xing Wei +6 more
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