Results 81 to 90 of about 3,117,738 (383)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Expression of FAT1 in Lung Adenocarcinoma and Its Relationship 
with Immune Cell Infiltration

Chinese Journal of Lung Cancer
Background and objective Lung cancer is a leading cause of cancer-related deaths. Non-small cell lung cancer (NSCLC) is the most common pathological subtype, with adenocarcinoma being the predominant type.
Chen DING, Wenhao ZHAO, Hua HUANG, Yongwen LI, Zhanrui ZHANG, Ruihao ZHANG, Yanan WANG, Di WU, Chen CHEN, Hongyu LIU, Jun CHEN   +10 more
doaj   +1 more source

Expression of ASPM in Lung Adenocarcinoma and Its Relationship with Development and Prognosis

Chinese Journal of Lung Cancer, 2020
Background and objective Previous studies have shown that ASPM is a tumorigenesis associated protein, mutations in ASPM can lead to MCPH. This study mainly explores the relationship between the ASPM expression of lung adenocarcinoma and the development ...
Junjie WANG, Zhenyu HE, Renhui DUAN
doaj   +1 more source

Uncovering the dynamic effects of DEX treatment on lung cancer by integrating bioinformatic inference and multiscale modeling of scRNA-seq and proteomics data [PDF]

arXiv, 2022
Motivation: Lung cancer is one of the leading causes for cancer-related death, with a five-year survival rate of 18%. It is a priority for us to understand the underlying mechanisms that affect the implementation and effectiveness of lung cancer therapeutics.
arxiv  

BAG Family Gene and Its Relationship with Lung Adenocarcinoma Susceptibility [PDF]

, 2010
Background and objective BAG genes (Bcl-2-associated athanogene) belong to a recently discovered multifunctional anti-apoptosis gene family that regulate various physiological processes which include apoptosis, tumorigenesis, neural differentiation ...
Heng WU, Hongyu LIU, Jiao YUE, Jing WANG, Jun CHEN, Qinghua ZHOU, Weiqiang WANG, Xinxin DU, Ying LI, Yongwen LI   +9 more
core  

Histogram-based models on non-thin section chest CT predict invasiveness of primary lung adenocarcinoma subsolid nodules. [PDF]

, 2019
109 pathologically proven subsolid nodules (SSN) were segmented by 2 readers on non-thin section chest CT with a lung nodule analysis software followed by extraction of CT attenuation histogram and geometric features.
Dmytriw, Adam A, Hwang, David M, Nguyen, Elsie T, Oikonomou, Anastasia, Paul, Narinder S, Petersen, Alexander, Salazar, Pascal, Zhang, Yuchen   +7 more
core   +2 more sources

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

Molecular Oncology, Volume 19, Issue 4, Page 1155-1169, April 2025.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park, Keeok Haam, Haejeong Heo, Doyeong Kim, Min‐Ju Kim, Hyo‐Jung Jung, Seongwon Cha, Mirang Kim, Haeseung Lee   +8 more
wiley   +1 more source

Classification of Histopathology Images of Lung Cancer Using Convolutional Neural Network (CNN) [PDF]

arXiv, 2021
Cancer is the uncontrollable cell division of abnormal cells inside the human body, which can spread to other body organs. It is one of the non-communicable diseases (NCDs) and NCDs accounts for 71% of total deaths worldwide whereas lung cancer is the second most diagnosed cancer after female breast cancer.
arxiv  

Clinico-pathologic profile and pattern of p53 expression of lung adenocarcinoma in non-smokers and smokers in a tertiary cancer centre [PDF]

Background: Lung cancer is the most common cause of cancer mortality worldwide. Smoking is undoubtedly the major risk factor of lung cancer in both genders.
A. L., Lijeesh, K., Jayasree, Khan N. S., Parwin, P., Sindhu Nair, Sukumaran, Renu   +4 more
core   +2 more sources

Identification of FKBP10 prognostic value in lung adenocarcinoma patients with surgical resection of brain metastases: A retrospective single-institution cohort study [PDF]

, 2023
Objective: To explore the expression levels and clinical value of FKBP10 in lung adenocarcinoma brain metastases. Design: A retrospective single-institution cohort study.
Cai, Hong-Qing, He, Jie, Li, Sai, Liu, Zhi-Dan, Wan, Jing-Hai, Wang, Shao-Hua, Wang, Song-Quan   +6 more
core   +1 more source