Results 51 to 60 of about 5,324,288 (181)

Transglutaminase in the life and death of the pancreatic β-cell [PDF]

, 2010
Tissue transglutaminase (TG2) is a ubiquitous enzyme that catalyses both the Ca2+-dependent formation of protein cross-links via intermolecular isopeptide bonds, and the Ca2+-independent hydrolysis of GTP.
Dookie, S
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Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production [PDF]

, 2017
Pancreatic-islet inflammation contributes to the failure of β cell insulin secretion during obesity and type 2 diabetes. However, little is known about the nature and function of resident immune cells in this context or in homeostasis.
Konrad, Daniel; https://orcid.org/, Daniela Finke, Marc Stawiski, Konrad, Daniel, Maechler, Pierre, Dalmas, Elise, Guigas, Bruno, Erez Dror, Constanze Thienel, Marcela Borsigova, Kerr-Conte, Julie, Donath, Marc Y, Stawiski, Marc, Traunecker, Emmanuel, Kallert, Sandra M, Wolfrum, Christian, Marc Y. Donath, Dianne H. Dapito, Stephan Wueest, Sandra M. Kallert, Dror, Erez, Thienel, Constanze, Lehmann, Frank M, Lucchini, Fabrizio C, Francois Pattou, Jean-Philippe Girard, Pierre Maechler, Emmanuel Traunecker, Christian Wolfrum, Marianne Böni-Schnetzler, Bruno Guigas, Julie Kerr-Conte, Girard, Jean-Philippe, Wueest, Stephan, Borsigova, Marcela, Fabrizio C. Lucchini, Dapito, Dianne H, Pattou, Francois, Finke, Daniela, Elise Dalmas, Böni-Schnetzler, Marianne, Frank M. Lehmann, Daniel Konrad, Lucchini, F.C., Maechler, P., Borsigova M, Finke D, Dapito, D.H., Lucchini FC, Maechler P, Kerr-Conte, J., Dror, E., Traunecker E, Traunecker, E., Lehmann, F.M., Kallert, S.M., Borsigova, M., Wueest S, Donath MY, Dalmas E, Stawiski M, Wueest, S., Thienel, C., Guigas B, Girard JP, Pattou, F., Konrad D, Thienel C, Girard, J.P., Dapito DH, Boni-Schnetzler, M., Kallert SM, Lehmann FM, Kerr-Conte J, Konrad, D., Finke, D., Donath, M.Y., Stawiski, M., Dalmas, E., Wolfrum C, Guigas, B., Böni-Schnetzler M, Dror E, Wolfrum, C., Pattou F   +84 more
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Neutron diffraction reveals sequence-specific membrane insertion of pre-fibrillar islet amyloid polypeptide and inhibition by rifampicin [PDF]

, 2005
Human islet amyloid polypeptide (hIAPP) forms amyloid deposits in non-insulin-dependent diabetes mellitus (NIDDM). Pre-fibrillar hIAPP oligomers (in contrast to monomeric IAPP or mature fibrils) increase membrane permeability, suggesting an important ...
Bradshaw, Jeremy, Hauss, T, Balali-Mood, K, Bradshaw, J. P., Balali-Mood, K., Ashley, R.H., Ashley, R. A., Ashley, R H, Balali Mood, K., Hau , T., Bradshaw, J.P., Hauss, Thomas   +11 more
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ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids

Blood vessels play a critical role in pancreatic islet function, yet current methods for deriving islet organoids from human pluripotent stem cells (SC-islets) lack vasculature.
Christman, Karen L., Hachey, Stephanie J., Bender, R. Hugh F., Kravets, Vira, Mallick, Medhavi, Zhu, Han, Sai, Somesh, Nguyen-Ngoc, Kim-Vy, Gong, Winnie, Schlichting, Michael, Gaetani, Roberto, Sander, Maike, Hughes, Christopher C.W., George, Steven C., Jun, Yesl, Hatch, Christopher J., Hughes, Christopher C. W.   +16 more
core   +1 more source

Signet-ring cell adenoma of the thyroid and rheumatoid arthritis: incidental association or methotrexate-related change?

, 2017
NA (Letter to the Edito section) Signet-ring cell adenoma of the thyroid and rheumatoid arthritis: incidental association or methotrexate-related change? Signet-ring cell change in thyroid adenoma is rarely reported [1-3].
Adriana Handra-Luca
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Malignant insulinoma: The problems of tumour localization and management [PDF]

, 2017
A case of malignant insulinoma in a Black patient is presented. An investigational protocol is suggested with a discussion of the newer techniques of pancreatic adenoma localization and the therapeutic measures available for the management of malignant ...
Wellsted, M, Svensson, L. G.
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ADENOMA OF ISLET CELLS WITH HYPERINSULIXISM

Annals of Surgery, 1935
A O, Whipple, V K, Frantz
openaire   +3 more sources

Islet cell transplantation for the treatment of type 1 diabetes: recent advances and future challenges

, 2014
Anthony Bruni, Boris Gala-Lopez, Andrew R Pepper, Nasser S Abualhassan, AM James Shapiro Clinical Islet Transplant Program and Department of Surgery, University of Alberta, Edmonton, AB, Canada Abstract: Islet transplantation is a well-established ...
Shapiro AM, Bruni A, Pepper AR, Gala-Lopez B, Abualhassan NS   +4 more
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Uncontrolled insulin secretion from a childhood pancreatic β-cell adenoma is not due to the functional loss of ATP-sensitive potassium channels

, 2002
We report the case of an 8-year-old child who presented with severe hyperinsulinaemic hypoglycaemia due to a pancreatic islet cell adenoma. In vivo, there was no beneficial response to the hyperglycaemia-inducing agent diazoxide and as a consequence the ...
Kassem, S. A., Hussain, K., Chapman, J. C., Glaser, B., Cosgrove, K. E., Aynsley-Green, A., Swift, S. M., Dunne, M. J., Smith, V. V., Shepherd, R. M., Lindley, K. J.   +10 more
core   +1 more source