Presumed Neuroglycopenia Caused by Severe Hypoglycemia in Horses. [PDF]
BackgroundNeuroglycopenia refers to a shortage of glucose in the brain resulting in neuronal dysfunction and death if left untreated. Presumed neuroglycopenia has not been described in horses.ObjectiveTo report neurological signs in horses with presumed ...
Aleman, M +3 more
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Heterogeneity of proliferative markers in pancreatic β-cells of patients with severe hypoglycemia following Roux-en-Y gastric bypass. [PDF]
Severe postprandial hypoglycemia with neuroglycopenia is an increasingly recognized, debilitating complication of Roux-en-Y gastric bypass (RYGB) surgery.
Folli, F. +9 more
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Somatostatin receptors in gastroentero-pancreatic neuroendocrine tumours [PDF]
Five somatostatin receptor (sst) subtype genes, sst(1), sst(2), sst(3), sst(4) and sst(5), have been cloned and characterised. The five sst subtypes all bind natural somatostatin-14 and somatostatin-28 with high affinity.
Herder, W.W. (Wouter) de +3 more
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Molecular Mechanisms of Secreting Vesicle Biogenesis and Secretion in Chronic Degenerative Diseases [PDF]
Regulated trafficking and secretion of insulin by the β cell of the endocrine pancreas is critical to maintain our body energy homeostasis. Disruption of these processes typically leads to hyperglycemia and the complications of diabetes.
Qiao, Xinxian
core
Dissociation between the effects of somatostatin (SS) and octapeptide SS-analogs on hormone release in a small subgroup of pituitary- and islet cell tumors [PDF]
The effects of somatostatin (SS-14 and/or SS-28) and of the three octapeptide SS-analogs that are available for clinical use (octreotide, BIM-23014 and RC-160) on hormone release by primary cultures of 15 clinically ...
Herder, W.W. (Wouter) de +9 more
core +3 more sources
Islet-cell adenoma of the pancreas
No ...
Merlin, M.B., Blignault, W. J.
openaire +1 more source
A panel of genes methylated with high frequency in colorectal cancer [PDF]
Background: The development of colorectal cancer (CRC) is accompanied by extensive epigenetic changes, including frequent regional hypermethylation particularly of gene promoter regions.
Aidan McEvoy +19 more
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Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin [PDF]
Somatostatin (SST) is a regulatory peptide and acts as an endogenous inhibitory regulator of the secretory and proliferative responses of target cells. SST's actions are mediated by a family of seven transmembrane domain G protein-coupled receptors that ...
Abrol, Ravinder +10 more
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Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion [PDF]
The epithelial-to-mesenchymal transition (EMT) is an important mechanism for cancer progression and metastasis. Numerous in vitro and tumor-profiling studies point to the miR-200–Zeb1 axis as crucial in regulating this process, yet in vivo studies ...
Bartel, David +7 more
core +3 more sources
Reg IV in human body and diseases [PDF]
Inflammatory bowel diseases (IBD) and cancers of the gastrointestinal (GI) tract cause considerable morbidity and mortality. In order to enhance the diagnostics and therapeutic measures, the biology of these diseases needs to be better understood ...
Maille, Kukka
core

